Başkent Üniversitesi Yayınları

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    A Case of Progressive Mortal Thrombosis: Phlegmasia Cerulea Dolens
    (Başkent Üniversitesi, 2023-03) Khalid Zeynalov; Burak Ozkan; Tankut Akay; A. Cagri Uysal; Mehmet Haberal
    ABSTRACT Phlegmasia cerulea dolens is a very rare set of conditions associated with acute, massive venous thromboembolism. Medical and surgical options can be combined in treatment. Patients may experience sudden onset and severe leg pain, edema, cyanosis, compartment syndrome, and post-venous gangrene amputation and death. Medical and surgical treatments can be combined in treatment. Anticoagulants, thrombectomy, percutaneous procedures and amputations are among the treatment options. We present a 60-year-old female patient with a diagnosis of diabetes mellitus with swelling, pain, and discoloration in the left lower extremity who died due to progressive venous thrombosis despite various treatment modalities. Wound debridement and thrombectomy were performed. On day 10 of hospitalization, the patient was intubated to treat resistant low saturation. Despite the interventions, the patient died on day 10 of hospitalization due to cardiopulmonary arrest. Early diagnosis and treatment are vitally important. As in the case we presented, sometimes patients die as a result of rapid clinical progression and side effects, despite the use of different medical and surgical treatments.
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    The Use of Growth Factors in Wound Healing: An Update
    (Başkent Üniversitesi, 2023-03) A. Cagri Uysal; Burak Ozkan; Orkhan Shahbazov; Ebru Sakallioglu Abali; Mehmet Haberal
    ABSTRACT Wound healing is a complex and well-integrated process. Growth factors have an important role in modulation of wound healing steps. Because of their important role in wound healing, growth factors have been used as triggering agents in chronic wounds. In this article, we provide an up-to-date review of growth factors found to be effective in chronic ulcers and are commercially available on the market for treatment of chronic ulcers.