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    Glycerol Affects Vestibular-Evoked Myogenic Potentials and Pure-Tone Hearing in Patients with Meniere's Disease
    (2015) Oz, Isilay; Erbek, Seyra Hatice; Alp, Gulfem; Hizal, Evren; Ozluoglu, Levent Naci; 0000-0002-8453-6069; 0000-0002-7380-4566; 0000-0002-2150-0237; 0000-0002-9699-6783; 25428817; AAJ-2445-2021; AAJ-1452-2021; AAI-8020-2021; A-5853-2018
    Conclusion: The pure-tone audiometry results following glycerol administration indicated a positive effect on cochlear endolymphatic hydrops. Glycerol cervical vestibular-evoked myogenic potential (cVEMP) tests are a useful means of diagnosing saccular hydrops. There was no correlation between cVEMP and audiological results. Objective: To document the changes in pure-tone hearing outcomes and cVEMPs in patients with Meniere's disease (MD) and 10 healthy volunteers before and after oral administration of glycerol. Methods: Twenty-nine study group subjects were chosen with complaints of vertigo. cVEMP testing and pure-tone hearing level testing were performed before and at 1, 2, and 3 h after administration of glycerol. Results: The means of the latencies, amplitudes, and difference ratio in 20 normal subject ears were determined. Based on these values, 9/29 MD-affected (MDA) ears (31%) had a unilaterally absent cVEMP. Compared with difference ratio values of the control groups there were significant differences in both latencies and amplitudes in MDA ears after glycerol administration. Before glycerol administration, there were significant differences between control and MDA ears on mean values of pure-tone hearing outcomes. Twenty patients in the MDA group showed significant pure-tone hearing outcomes after glycerol administration.
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    Evaluation of Benign Paroxysmal Positional Vertigo Following Le Fort I Osteotomy
    (2017) Deniz, K.; Akdeniz, S. S.; Koc, A. O.; Uckan, S.; Ozluoglu, L. N.; 0000-0002-2150-0237; 0000-0002-3798-7326; 27856148; AAI-8020-2021
    The Le Fort I osteotomy is widely used to correct dentofacial deformities. Benign paroxysmal positional vertigo (BPPV) is a common vestibular end organ disorder characterized by short, often recurrent episodes of vertigo. Head trauma is one of the known causes of BPPV. During pterygoid osteotomy, the surgical trauma induced by percussion with the surgical mallet and osteotomes can displace otoliths into the semicircular canal, resulting in BPPV. The aim of this study was to evaluate the potential risk of occurrence of BPPV in individuals undergoing Le Fort I osteotomy. Twenty-three patients were included in this study. The Dix-Hallpike manoeuvre, positional tests using electronystagmography, and vestibular evoked myogenic potential (VEMP) tests were performed 1 week before surgery (TO), 1 week after surgery (T1), and 1 month after surgery (T2). The results were compared statistically. BPPV was observed in three patients. Eleven patients had nystagmus at the T1 evaluation and seven at the T2 evaluation. The difference between the TO and T1 time points was statistically significant (P = 0.001). BPPV is a possible complication of Le Fort I osteotomy. Surgeons should be aware of this complication, and the diagnosis of BPPV should be considered in patients who have undergone Le Fort I osteotomy.
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    High riding jugular bulb: Is it an etiological factor for benign paroxysmal positional vertigo?
    (2021) Çoban, Kuebra; Kansu, Leyla; Ergun, Tarkan; Aydin, Erdinc
    Introduction: High jugular bulb (HJB) is usually discovered incidentally; however, it may interfere with inner ear structures such as vestibular aqueduct (VA), facial nerve, and the posterior semicircular canal (PSCC). Objective: The aim is to investigate the incidence of HJB in benign paroxysmal positional vertigo patients with PSCC involvement (PSCC-BPPV). Materials and Methods: The study group included 53 consecutive, PSCC-BPPV patients, diagnosed in our clinic. Following the diagnosis, their high resolution computed temporal bone tomography were performed. The control group consisted of 90 patients, who attended to our clinic for various complaints, and to whom high resolution computed tomography of the temporal bone was conducted. Results: The incidence of HJB in the study group was 41.5% (n = 22). The incidence of ipsilateral HJB in this group was 28.3% (n = 15). The incidence of HJB in the control group was 11.1% (n = 10) (P < 0.001). The closest distance between HJB and PSCC canal in the control and study groups was 1.61 +/- 0.74 mm and 1.17 +/- 0.37 mm, respectively (P = 0.098). Conclusion: The HJB is significantly more frequent in PSCC-BPPV patients. Furthermore, the rate of incidence of HJB in the ipsilateral ears of these patients is significantly higher. Venous hypertension or the turbulence may cause strong pulsations, which influence the detachment of the otoconia into the PSCC.