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Subject: search.filters.subject.Vasculitis

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    Cyclophosphamide Therapy During the Covid19 Pandemic
    (2023) Bitik, B.; Oygur, C. S.; Kanbur, A. Yalcintas; Yucel, A. E.
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    Performance of 2022 Acr/Eular Gpa, Egpa and Mpa Classification Criteria in Turkish Vasculitis Study Group Prospective Cohort (TRVAS)
    (2023) Bolek, E. C.; Ayan, G.; Bilgin, E.; Ediboglu, E. Durak; Duran, E.; Kardas, C.; Yildirim, T. Demirci; Ozdemir, B.; Ogut, T. S.; Karabacak, M.; Cagdas, O. Sadioglu; Yildirim, R.; Erpek, E.; Ozgur, D.; Akleylek, C.; Acar, E. A.; Uludogan, B. C.; Unaldi, E.; Uzun, G. Sandal; Ekici, Z. Ozsoy M.; Firlatan, B.; Kart-Bayram, S.; Kutu, M. E.; Mutlu, M. Yalcin; Armagan, B.; Gercik, O.; Bitik, B.; Kucuk, H.; Yilmaz, N.; Bilge, N. S. Yasar; Celik, S.; Kilic, L.; Kasifoglu, T.; Yazici, A.; Bes, C.; Erden, A.; Erbasan, F.; Asicioglu, E.; Alibaz Oner, F.; Omma, A.; Cefle, A.; Yazisiz, V.; Ozturk, M. A.; Direskeneli, H.; Kiraz, S.; Onen, F.; Akar, S.; Karadag, O.
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    Optical coherence tomography angiography findings in Behcet patients
    (2019) Emre, Sinan; Guven-Yilmaz, Suzan; Ulusoy, Mahmut Oguz; Ates, Halil; 30710254
    PurposeRetinal vasculitis and vein occlusions are common causes of serious visual loss in Behcet's disease. We aimed to evaluate the optical coherence tomography angiography (OCTA) findings of Behcet uveitis (BU) patients.MethodsWe evaluated 32 eyes of 16 patients with BU and 30 eyes of 15 healthy controls. Superficial capillary plexus (SCP) and deeper capillary plexuses (DCP) were evaluated using OCTA RTVue XR AVANTI.ResultsOn SCP, nonperfusion/hypoperfusion areas (NPA) were seen in 10 eyes, perifoveal capillary arcade disruption (PCAD) was seen in 10 eyes, capillary network disorganization (CND) was seen in 7 eyes and intraretinal cystoid spaces (ICS) were seen in 2 eyes. On DCP, NPA were seen in 13 eyes, PCAD was seen in 11 eyes, CND was seen in 7 eyes and ICS were seen in 4 eyes.ConclusionWe showed that DCP were affected more than SCP in these patients. In addition, capillary vessel density of BU group was significantly lower than control group.
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    Granulomatous polyangitis (Wegener granulomatosis): Clinical findings and results of long-term follow-up
    (2016) Sen, Nazan; Aydin Tufan, Muge; Yildiz, Reyhan; Ersozlu Bozkirli, Emine Duygu; Yucel, Eftal; 0000-0002-4171-7484; 28393729; AAI-8947-2021
    Introduction: To evaluate long-term outcome of patients with granulomatous polyangitis (GPA) followed up in a tertiary university hospital. Patients and Methods: We reviewed medical records of 22 patients with GPA diagnosis confirmed by tissue biopsies between 2004 and 2014. Results: The mean time from the onset of symptoms to diagnosis was 7.8 +/- 12.3 months [interquartile range (IR)= 4.0]. The most commonly involved organs were the upper respiratory tract (URT) (72.7%), lower respiratory tract (81.8%) and kidneys (72.7%). URT involvement indicated good prognosis (p= 0.046). Survival in the patients with and without URT involvement was 124.6 +/- 6.9 months and 59.7 +/- 22.9 months, respectively. End-stage renal failure (ESRF) requiring dilaysis and cardiac involvement were associated with mortality (p= 0.022 and p= 0.026, respectively). Of the 12 dialysis-dependent patients at diagnosis, 11 survived > 3 months and seven regained renal function permanently. Dialysis dependency was significantly lower in patients who received plasmapheresis (p= 0.047). Overall mortality rate was 18% (4/22). Mean survival was 55.9 +/- 42.8 months (IR= 84.0). Conclusion: Diagnosis of GPA may be delayed by the nonspecific nature of its symptoms. URT involvement was associated with good prognosis, whereas cardiac involvement and ESRF requiring dialysis were associated with poor outcome. Plasmapheresis may increase the rate of renal recovery in the patients with ESRF requiring dialysis.