Fakülteler / Faculties

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Subject: search.filters.subject.Microsurgery

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    Configuration of Hardware for Medical Plasma Based Surgical Device and Features
    (2018) Recber, Deniz; Kayserilioglu, Batuhan; Kocum, Ismail Cengiz; Cokeliler Serdaroglu, Dilek
    This research, covers the evaluation of the performance of harware of plasma-based (gas plasma, plasma jet) surgical prototype device which will be used in microsurgery, identification of active device operating conditions with the appropriate engineering models Microsurgery is by taking advantage of the magnifying effect of the special operation microscope, very small structures that can hardly be seen with the naked eye and surgery using very thin instrument. It is necessary to emphasize, the plasma technique using on directly liver cell for the treatment is the novel study. The examples of portable commercial devices in the world have started to increase in the recent past, but they are still few. The project has three main design in general; primarily high voltage power supply, bipolar plasma probe, gas supply control unit made it. High voltage power supply made with transformator and mosfets connecting with push-pull. Bipolar plasma probe, made 2 tungsten rod which mounted on the board mechanism and used teflon wire for connection with high voltage power supply. For the gas supply control unit, used microprocessor controlled and transistor amplifier selenoid valve. Thus, it is aimed to trigger the solenoid valve and adjust the gas flow in the adjustable frequency range. In the first tests made, the formation of radiation of the high voltage circuit was observed. The integration with the tungsten probe system was completed and tried to test the relation between angle and distance and radiation. In addition, the completed parts of the gas supply control unit designed together with the solenoid valve and the microprocessor have been tested. etc.] in its style sheet. As a result, the distance parameter of radiation formation is determined by high voltage circuit tests. Radiation-angle tests were performed and later turned into a prototype with the outer design of the device.
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    Successful Replantation of Tamai Zone I Amputation with Delayed Vein Repair
    (2021) Ozkan, Burak; Uysal, Ahmet Cagri; Markal Ertas, Nilgun; https://orcid.org/0000-0003-3093-8369; https://orcid.org/0000-0001-6236-0050; 33477171; AAJ-2949-2021
    Digital vein repair is one of the most challenging phases of distal phalanx replantation. Digital veins at very distal levels have a small vessel caliber and collapsed lumens, which makes them hard to identify and handle. Digital veins may not be visible immediately after arterial anastomosis. In this scenario, the patient can be taken to the operative room several hours after revascularization to visualize dilated and expanded veins for late digital vein repair. Late digital vein repair is a reliable and alternative method to artery only replantation. In this report, a successful replantation with late digital vein repair in Tamai Zone I is presented
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    The effect of ticagrelor on microarterial thrombosis in an experimental model
    (2021) Okur, Mehmet Ihsan; Cetinbas, Ahmet; Altun, Serdar; Oztan, Mehmet; Altun, Aysun Yildiz; Ozercan, Ibrahim; 33593206
    Thromboses that form in the pedicle after free flap and/or replantation may result in the loss of the flap and/or limb. Ticagrelor is an adenosine diphosphate (ADP) receptor antagonist antithrombotic that can inhibit ADP-dependent platelet activation and aggregation. It is clinically used in acute coronary syndrome and unstable angina. However, its effect on microarterial anastomoses has not been investigated in the literature. An experimental thrombosis model was developed in both femoral arteries of a total of 40 rats. Twenty rats were randomly selected as the drug-free control group, and 20 rats were randomly selected as the ticagrelor group. The rats in the ticagrelor group were administered a 20 mg/kg loading dose orally by gavage 24 h before the experiment, and a maintenance dose of 2x10 mg/kg ticagrelor for 14 days after surgery. After the experiment, the femoral artery was evaluated for macroscopic and microscopic thrombosis, inflammation, edema, and endothelialization. Macroscopically and microscopically, thrombosis was observed at rates of 73.3% and 33.3% in the control group and the ticagrelor group, respectively. Inflammation in the vessel wall was found as 56.7% in the control group and 16.7% in the ticagrelor group. Edema in the vessel wall was found in 63.3% of the control group and 20% of the ticagrelor group. A statistical difference was found between the two groups in terms of thrombosis, inflammation, and edema. Both groups had similar characteristics in terms of endothelialization. Ticagrelor has a reducing effect on thrombosis in the microarterial tuck model.