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Subject: search.filters.subject.Distraction osteogenesis

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    Effects of Osteoformin in The Rapid Distraction Osteogenesis of Rabbit Mandibles
    (2016) Dayisoylu, Ezher Hamza; Pampu, Alper; Senel, Figen Cizmeci; Onder, Ercument; Dolanmaz, Dogan; Altintas, Nuray Yilmaz; Avunduk, Mustafa Cihat; https://orcid.org/0000-0002-1859-2003; https://orcid.org/0000-0002-1488-616X; https://orcid.org/0000-0003-4155-1426; https://orcid.org/0000-0002-8709-8949; 26819154; AAY-5342-2020; P-8463-2015; AAS-8398-2020; ABI-4613-2020
    Objective: To evaluate the effects of osteoformin on mineralisation and quality of the new bone formation during rapid distraction osteogenesis. Methods: This multi-centre study was conducted at the Karadeniz Technical University, Middle East Technical University and Selcuk University. The experimental study was conducted fromJanuary 2010 to September 2012 and comprised New-Zealand rabbits that were randomly divided into three groups. In group I distraction rate was 1 mm/day while in groups II and III distraction rates were 2mm/day and 1 mm/day. In groups I and II 100 mu g/kg osteoformin was injected after the latency period. Distraction region was evaluated by radiological, histomorphometrical and dual energy X-ray absorptiometry analyses. SPSS 17 was used for statistical analysis. Results: There were 18 rabbits with each of three groups having 6(33.3%). Accelerated bone healing was noted in groups I and II compared with group III (p<0.05). No significant differences were indicated between groups I and II (p>0.05). Conclusion: Local injection of osteoformin was effective in the craniomaxillofacial distraction osteogenesis in rabbits. Further experimental studies are recommended before using osteoformin on humans.
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    Combined use of alveolar distraction osteogenesis and segmental osteotomy in anterior vertical ridge augmentation
    (2015) Oncu, Elif; Isik, Kubilay; Alaaddinoglu, E.Emine; Uckan, Sina; 0000-0001-6718-3882; 25661636
    INTRODUCTION: Vertical defects of the anterioral veolar ridge are challenging cases in implant dentistry. Various techniques, such as onlay bone grafting, segmental osteotomy (SO) oral veolar distraction osteogenesis (ADO), have been suggested to manage those situations. ADO has an advantage of being capable of enhancing both hard and soft tissue simultaneously. PRESENTATION OF CASE: One of the possible complications of ADO is rotation ortilting the transport segment (TS). In this report, we present a 30-year old woman who had a severe anterior vertical deficiency. ADO was started to manage the case, but advancement of the TS lagged on the left side and the segment rotated. A SO was planned and the lagged side was corrected. Two years after the surgery, hard and soft tissue gains were found to be preserved. DISCUSSION: Vertical alveolar bone deficiencies are challenging cases for dental implantology. Alveolar DO promotes soft tissue along with hard tissue, and the bone regeneration process and shows lower infection rates and greater stability over the long term. However, the technique has some disadvantages and can lead to complications, such as breaking of the distraction device, nerve injury or paresthesia, fracture of transport bone, hematoma, wound dehiscence, severe bleeding, and even jaw fractures. Deviation of the TS from the distraction path is another undesired situation. The rigidity of the device, the width of the mucosa, the volume of the transport and anchor segments, and the amount of augmentation can affect vector deviation. CONCLUSION: We suggest that SO can be used in similar cases in which TS could not be distracted on a straight vector line. (C) 2015 Published by Elsevier Ltd. on behalf of Surgical Associates Ltd.