Fakülteler / Faculties

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    Successful Renal Transplantation, Bone Mineral Densitometry, and Affecting Factors
    (2015) Canoz, M. B.; Yavuz, D.; Altunoglu, A.; Yavuz, R.; Colak, T.; Haberal, M.; 0000-0002-3462-7632; 0000-0002-4082-6320; 0000-0002-8372-7840; 26293056; AAJ-8097-2021; ABG-9980-2021; AAJ-8554-2021
    Background. Successful renal transplantation corrects many disorders of bone and mineral metabolism owing to the normalization of serum levels of calcium and phosphorus and restoration of calcitriol production. However, successful transplantation does not guarantee complete resolution of the pre-transplantation osteopathy. Methods. This study evaluated 100 patients who underwent successful renal transplantation. We determined the possible risk factors for osteoporosis among 72 male and 28 female renal transplant patients of mean age 32.3 +/- 10.0 years with 81% of them recipients of living-related grafts. Bone mineral densitometry (BMD) was performed in all patients before and >= 1 year after transplantation. Routine test results and demographic data were recorded. Results. At the time of transplantation 76% of the patients had osteoporosis or osteopeni and only 24% of them had normal BMD in 4 regions (femur neck, lumber, radius, and ultradistal). After transplantation, 70% of them had osteopororosis or osteopeni and 30% were normal. After renal transplantation, BMD scores increased (P > .05) although the diagnosis of the bone disease did not change (P < .05). Only preexisting osteodystrophy and smoking were found to be important risk factors for post-transplantation osteoporosis. Conclusions. After renal transplantation, BMD scores increased whereas the diagnosis of bone disease did not change statistically. We found that medical management of osteopenia/osteoporosis before transplantation and smoking habit are the main factors to prevent post-transplantation osteoporosis. Further long-term studies may be more helpful for evaluating the risk factors of post-transplantation osteoporosis.
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    Effect of Dry Eye on Scheimpflug Imaging of the Cornea and Elevation Data
    (2017) Asena, Leyla; Alnors, Dilek D.; Cezairlioglu, Sefik; Boluk, Sefer Oguen; https://orcid.org/0000-0002-6848-203X; 28576215; E-5914-2016
    Objective: To evaluate the effect of dry eye on Scheimpflug imaging of the cornea and elevation data. Design: Prospective observational study. Participants: Scheimpflug images of 50 patients with dry eye who were being tested for eligibility for corneal refractive surgery were screened. Twelve eyes of 12 patients with abnormal Belin/Ambrosio enhanced ectasia display (BAD) anterior elevation difference were included in the study. The patients had no history of contact lens wear or any other sign of ectasia. Methods: Peak central corneal densitometry value, corneal volume, pachymetry at the thinnest point, and BAD anterior elevation difference value at the centre of the 9 mm zone were recorded before and after 4 weeks of dry eye treatment. Measurements were compared with the Wilcoxon signed rank test. Results: The mean corneal peak densitometry and volume were similar before and after therapy (p = 0.465 and p = 0.441, respectively). The mean anterior elevation difference value at the centre of the 9 mm zone before treatment (6.67 +/- 1.72 mu m) was significantly higher than the mean post-treatment value (4.00 +/- 1.48 mu m) (p = 0.002). The mean pachymetry at the thinnest location after treatment (548 +/- 11.0) was significantly higher than the pretreatment value (538 +/- 8.5) (p = 0.027). Conclusions: BAD anterior elevation differences and pachymetric measurements may be affected by ocular surface or tear film abnormalities associated with dry eye disease. Repeated evaluations after treatment may reveal normal results.