Fakülteler / Faculties

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    Transience and the Modern Turkish Interior
    (2023) Hasirci, Deniz; Ultav, Zeynep Tuna; Sumnu, Umut; AAC-5579-2020
    Despite the expansion of research in modern interiors around the world and a more inclusive dialogue with regards to geography, ultimately, the field is still lacking theory and methods derived from its own specific needs rather than being adapted from architectural research, and a focus on its transient nature that is likely to lead to more impactful research and preservation results. Modern Turkish interiors research have also expanded greatly with individual, as well as projects or research groups like docomomo_tr interiors and DATUMM (Documenting and Archiving Modern Turkish Furniture) that create awareness through various forms of scholarly (documentaries, archival work) and popular (public exhibitions, popular books and magazines, newspaper pieces, and films) interiors research and several struggles are common worldwide, socio-cultural and economic reasons result in a faster pace in Turkey, creating an urgency to implement innovative methods and approaches fitting contemporary prerequisites of the field.
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    The Power Bases in Multiplayer Video Games
    (2023) Omerbas, Ali Cagil
    This study deals with how players employ different power relations while playing videogames. Power is a difficult concept to define but it is usually explained with the ability to influence. Social psychologists John French and Bertram Raven's studies have defined five bases for social influence: coercive (based on punishment), referent (based on affection), reward (based on reward), expert (based on expertise) and legitimate (based on agreed regulations) powers. Many other studies have tested their theory in various fields, and it proved to be a lasting one. Researchers conducted studies in areas such as education, business, sports with this theory and obtained meaningful results. However, the power bases of video game players has never been studied, despite the fact that video game studies has already been established as an academic field -with many scholars discussing empowerment through games. This study focuses on measuring the power of a player over another one. There can be two types of such relations: it can either take place among players in an everybody-for-themselves kind of environment - which is called inter-power relations, or it can take place between the members of a team, working together for a common goal. This is called intra power relations. This study demonstrates that expert and reward powers are preferred in inter and intra-power relations, referent being another valid option for teamwork.
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    Intelligent Optimization Under the Makespan Constraint: Rapid Evaluation Mechanisms Based on the Critical Machine for the Distributed Flowshop Group Scheduling Problem
    (2023) Wang, Yuhang; Han, Yuyan; Wang, Yuting; Tasgetiren, M. Fatih; Li, Junqing; Gao, Kaizhou
    In the flowshop scheduling literature, the insertion-based neighborhood search method is often considered to obtain high-quality solutions. It will lead to expending extensive computational effort when evaluating the objective function. Rapid evaluation methods based on Taillard's acceleration can reduce the time complexity of function evaluation. However, existing rapid evaluation methods cannot be applied directly to the distributed flowshop group scheduling problem (DFGSP), especially to minimize the total tardiness time objective. Thus, we first proposed two theorems and their proofs based on the critical machine. Then, two rapid evaluation methods based on these theorems are proposed to accelerate the evaluation of the objective. Considering the multiple coupled sub-problems in the DFGSP, we proposed a cooperative iterated greedy algorithm (CIG) combining two rapid evaluation methods, in which intergroup and intra-group neighborhood search strategies are proposed to enhance the search depth and breadth. Comprehensive statistical experiments show that computational effort is extensively decreased in the calculation of total tardiness time, and the CIG algorithm significantly outperforms the eight compared algorithms.& COPY; 2023 Elsevier B.V. All rights reserved.
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    The Influence of Different Sugammadex Doses on Neural Tube Development in Early-Stage Chick Embryos
    (2023) Ayhan, Asude; Efe, Ekin; Fidan, Pinar A.; Efe, Oguzhan E.; Ates, Eylem Gul; Sahinturk, Fikret; Ayhan, Selim; 0000-0002-6166-2601; 0000-0001-6955-9839; 0000-0002-3243-7843; 0000-0003-3047-0305; 0000-0002-0471-3177; 37565787; HGE-9282-2022; AAJ-2057-2021; AAJ-4728-2021; W-7908-2019; ABG-5365-2020; AAI-7972-2021
    Background: Sugammadex is a modified gamma-cyclodextrin that has been developed with the goal of reversing the steroidal neuromuscular blocking agents. The aim of the present study is to investigate the effects of different sugammadex doses on embryologic and neural tube development in an early-stage chick embryo model. Methods: A total of 100 specific pathogen-free, fertilized domestic chicken eggs were randomly divided into five groups (n = 20, each), and placed in an automatic cycle incubator. The eggs in the "control (C)" group were incubated without administration of any drug till the end of the experiment. Subblastodermic administration of 0.9% NaCl as vehicle control (VC) and different doses of sugammadex solutions prepared with the latter [2 mg/mL (LD), 4 mg/mL (MD), 16 mg/mL (HD)] were performed at 30 hr of incubation. All embryos were removed from the eggs at 72 hr when they were expected to reach Hamburger-Hamilton (HH) stages 19-20, then they were fixed, and evaluated histo-morphologically. Results: Embryonic development was not observed in 11 eggs (1 in C, 1 in VC; 3 in LD, 3 in MD, and 3 in HD). All the developed embryos were compatible with the HH stages 19-20. A neural tube closure defect was detected in one embryo in the HD group. No statistically significant difference was found between the groups in terms of embryonic and neural tube developments. Conclusions: No significant association was found between the drug and adverse outcomes; however, a trend with dosing was seen. Further studies are required before conclude on safety and extrapolate these results to human beings.
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    Comment on: Intensity Modulated Radiotherapy in Head and Neck Cancer: Initial Experience of the First Treated Cases from North-East India
    (2023) Topkan, Erkan; Somay, Efsun; Selek, Ugur; 0000-0001-8251-6913; 38187854; AAG-2213-2021; O-5474-2014
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    The Effect of Acupressure Applied to Different Fistula Area on Fistule Needle Entry Pain
    (2023) Turgay, Gulay; Cevik, Banu; Inanoglu, Isilay; Kaya, Semiha; AAN-3284-2021
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    The Effect of Glomerular C3 Deposition on Renal Outcome in Patients with Membranous Nephropathy: Data of the Tsn-Gold Study
    (2023) Gursu, Meltem; Ceheci, Egemen; Turkmen, Aydin; Dervisoglu, Erkan; Sezen, Mehnet; Turgutalp, Kenan; Sahin, Gulizar Manga; Trablus, Sinan; Kutlay, Sim; Uzun, Sami; Ustundag, Sedat; Dursun, Belda; Ayli, Deniz; Tatar, Erhan; Oztop, Kenan Evren; Basturk, Taner; Cevher, Simal Koksal; Yilmaz, Zulfikar; Tunca, Onur; Sevinc, Mustafa; Yadigar, Serap; Duranay, Murat; Arikan, Izzet Hakki; Elciuglu, Omer Celal; Karakan, Sebnem; Turkmen, Kultigin; Torun, Dilek; Gungor, Ozkan; Artan, Ayse Serra; Ozturk, Savas; Unsal, Abdulkadir; Seyahi, Nurhan; AAD-9111-2021
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    Characteristics and Survival Data of Patients with Primary Focal Segmental Segmental Glomerulosclerosis: Tsn-Goldmulti-Center Study
    (2023) Dheir, Hamad; Cebeci, Egemen; Karadag, Serhat; Yildiz, Abdulmecit; Guller, Nurana; Altiparmak, Mehmet Riza; Eren, Necmi; Yilmaz, Zulfikar; Basturk, Taner; Sipahi, Savas; Sahin, Gulizar; Bakar, Betul; Okyay, Gulay Ulusal; Suleyman, Gultekin; Piskinpasa, Serhan Vahit; Dursun, Belda; Balal, Mustafa; Turgutalp, Kenan; Guzel, Fatma Betul; Kutlay, Sim; Tatar, Erhan; Elcioglu, Omer Celal; Karakan, Sebnem; Kayalar, Arzu Ozdemir; FarukAkcay, Omer; Yildirim, Tolga; Sahin, Idris; Sahin, Garip; Ogutmen, Melike Betul; Tokgoz, Bulent; Tunca, Onur; Gul, Cuma Bulent; Kurultak, Ilhan; Torun, Dilek; Ayar, Yavuz; Uzun, Sami; Yavuz, Mahmut; Oto, Ozgur Akin; Dincer, Mevlut Tamer; Ergul, Metin; Ozturk, Savas; Turkmen, Aydin; AAD-9111-2021
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    Transarterial Chemoembolization Combined with Simultaneous Thermal Ablation for Solitary Hepatocellular Carcinomas in Regions with a High Risk of Recurrence
    (2023) Ozen, Ozgur; Boyvat, Fatih; Zeydanli, Tolga; Kesim, Cagri; Karakaya, Emre; Haberal, Mehmet; 0000-0001-7122-4130; 37455470; JVO-4809-2024; AAD-5996-2021; AAD-5466-2021; F-4230-2011; AAN-1681-2021
    Objectives: We evaluated the safety and efficacy of transarterial chemoembolization combined with percutaneous thermal ablation (radiofrequency or microwave ablation) in the treatment of solitary hepatocellular carcinoma tumors ranging from 2 to 4.5 cm at subdiaphragmatic, subcapsular, or perivascular locations. Materials and Methods: Fifteen patients (12 men, mean [range] age of 66.6 +/- 10.88 [34-75] y) who received transarterial chemoembolization combined with simultaneous percutaneous radiofrequency ablation (n = 5) or microwave ablation (n = 10) for hepatocellular carcinoma in regions with high risk of recurrence (subdiaphragmatic, subcapsular, or perivascular) between 2012 and 2018 were evaluated. We retrospectively investigated tumor diameter and localization, success rate, safety, local efficacy (imaging at month 1 after treatment), local tumor response (3 months posttreatment), local tumor progression, intrahepatic distant recurrence, overall survival and complications. Results: Tumor diameter ranged from 20 to 45 mm (mean 31.7 +/- 7.37 mm). Hepatocellular carcinoma diameter was 2 to 3 cm in 7 patients and 3.1 to 4.5 cm in 8 patients. The technical success rate was 100%, with no life-threatening complications. At enhanced imaging at 1-month follow-up, the complete necrosis rate was 100%; at 3 months, 100% of patients had a complete response. During a mean follow-up of 26 +/- 13.6 months, 7 patients (46.7%) had tumor progression. Three patients (20%) had local tumor response, and 4 patients (26.7 %) experienced distant recurrences in the untreated liver. The mean local tumor progression and mean intrahepatic distance recurrence times were 11 months and 29.5 months, respectively. Overall survival rates were 100% at 1 year, 73% at 3 years, and 47% at 5 years. Conclusions: Transarterial chemoembolization combined with simultaneous percutaneous thermal ablation is safe, feasible, and effective in enhancing the local control rate for solitary hepatocellular carcinoma ranging from 2 to 4.5 cm in regions with high risk of recurrence.