Fakülteler / Faculties
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Item Tension-Free Primary Closure for the Treatment of Pilonidal Disease(2015) Arer, Ilker Murat; Yabanoglu, Hakan; Caliskan, Kenan; 0000-0002-1161-3369; 0000-0003-0268-8999; 0000-0002-8767-5021; 26567718; AAJ-7865-2021; AAK-2011-2021; AAJ-7201-2021AIM: Pilonidal disease (PD) is a common disorder that usually affects young population and generally seen in intergluteal region. Conservative and surgical treatment options have been utilized. Many surgical techniques including primary closure, marsupialization and flap procedures have been described. The present study aims to evaluate the optimal surgical method for the treatment of PD. MATERIAL AND METHODS: A total of 151 patients underwent pilonidal disease surgery between January 2007 and September 2014 were enrolled in this study. Patients were compared according to age, sex, operation time, length of RESULTS: A total of 151 patients with a mean age of 25.18 years (range 14-66) presented with pilonidal disease were evaluated. Primary closure (PC) and tension-free primary closure (TFPC) were performed in 105 (69.5%) and 46 (30.5%) patients, respectively. There was no statistical difference between groups according to age, sex, operation time and length of hospital stay. Only 9 patients (8.6%) in PC and 3 patients (65%) in TFPC have postoperative recurrent disease. of 17 patients (7.9%) dehiscence was seen, 15 (14.3%) were in PC group and 2 (4.3%) were in TFPC group. Postoperative seroma or wound infection was seen in 16 patients (10.6%). CONCLUSION: Tension-free primary closure is a method that is effective as primary closure.Item Early Infections in Renal Transplant Recipients: Incidence, Risk Factors, and Causative Microorganisms(2015) Yabanoglu, Hakan; Aliskan, Hikmet Eda; Caliskan, Kenan; Arer, Ilker; Akdur, Aydincan; Yildirim, Sedat; Moray, Gokhan; Haberal, Mehmet; 0000-0002-1161-3369; 0000-0002-8726-3369; 0000-0002-5735-4315; 0000-0001-9060-3195; 0000-0002-8767-5021; 0000-0002-3462-7632; 0000-0003-0268-8999; 0000-0003-2498-7287; 26640902; AAJ-7865-2021; AAA-3068-2021; AAF-4610-2019; AAE-2282-2021; AAJ-7201-2021; AAJ-8097-2021; AAK-2011-2021; AAE-1041-2021Objectives: This study aimed to compare renal transplant recipients with and without infection with respect to demographic and clinical characteristics as well as risk factors; to determine the incidence of posttransplant infections; and to study the antibiotic resistance patterns of bacterial species identified as the causative organisms in posttransplant infections. Materials and Methods: This study included a total of 136 patients undergoing renal transplant in a 4-year period. The patients were categorized into 2 groups. The 2 groups were compared with each other with respect to general clinical and demographic variables and the number and frequency of infectious attacks within a 1-year follow-up, infection type, and antibiotic resistance patterns. Results: Ninety-two (67.6%) of the subjects were male and 44 (32.4%) were female. A total of 57 (41.9%) patients developed 128 infectious attacks. Urinary tract infections were the most common infections (42.1%). There was a significant correlation between a clinically relevant urinary culture proliferation and postoperative infection rate (P =.002). There was a significant correlation between antimicrobial resistance and the number of infectious attacks (P =.023). There was a significant correlation between the proliferation of Extended Spectrum Beta Lactamase-positive Enterobactericeae species and the number of infectious attacks (P =.000). Conclusions: Presence of a clinically relevant proliferation in the preoperative urinary culture, which was identified as a risk factor for infection, increased the number of infectious attacks. Moreover, Extended Spectrum Beta Lactamase-positive Enterobactericeae species increased the number of infections. These 2 principle results should be taken into account in patient management.Item Comparison of the Early Term Complications and Patency Rates of the Standard (Parachute) and Diamond-Shaped End-To-Side Anastomosis Techniques in Arteriovenous Fistulas Created for Hemodialysis(2018) Yabanoglu, Hakan; Kus, Murat; Arer, Ilker Murat; Bali, Cagla; Avci, Tevfik; Akdur, Aydincan; Caliskan, Kenan; https://orcid.org/0000-0002-1161-3369; https://orcid.org/0000-0001-6529-7579; https://orcid.org/0000-0003-2615-1918; https://orcid.org/0000-0001-5225-959X; https://orcid.org/0000-0002-8726-3369; https://orcid.org/0000-0002-8767-5021; 30060787; AAJ-7865-2021; AAJ-7870-2021; AAI-8790-2021; AAF-1698-2021; AAA-3068-2021; AAJ-7201-2021Objective: To compare the early-term patency and complication rates of the end-to-side anastomosis techniques parachute and diamond-shaped techniques in arteriovenous fistulas. Study Design: Prospective randomised study. Place and Duration of Study: Department of General Surgery, Adana Baskent University Application and Research Hospital, Adana, Turkey, between October 2014 and January 2015. Methodology: Patients with end stage renal disease who underwent arteriovenous fistula creation for hemodialysis were grouped into two according to the anastomosis technique performed. Group 1 was composed of the patients undergoing the standard parachute technique and Group 2 consisted of the patients operated with the diamond-shaped anastomosis technique. The two groups were compared with each other with respect to clinical and demographic data, operative and postoperative variables, and complication and patency rates. Results: A total of 56 patients underwent arteriovenous fistula creation. The overall complication rate was 12.5%. The early-term patency rate was higher in the diamond-shaped anastomosis technique than the standard parachute end-to-side anastomosis technique. Effective dialysis was established after 4 weeks in 48 (85.7%) patients in the overall study group, 23 (82.1%) in Group 1, and 25 (89.2%) in Group 2. However, there was no significant difference between both the techniques with respect to effectiveness of dialysis. Conclusion: Both end-to-side anastomosis techniques have their own advantages and disadvantages. Using a patient-specific suitable technique rather than a standard technique would be more appropriate in arteriovenous fistulas formation.Item Assessment of Atrial Fibrillation and Ventricular Arrhythmia Risk after Transplantation in Patients with End Stage Renal Disease by P Wave/QT Interval Dispersion, Tp-e Interval, Tp-e/QT Interval Ratio(2018) Yilmaz, Mustafa; Altin, Cihan; Tekin, Abdullah; Arer, Ilker; Yabanoglu, Hakan; Caliskan, Kenan; Moray, Gokhan; Ozin, Bulent; Muderrisoglu, Haldun; Haberal, Mehmet; https://orcid.org/0000-0002-2557-9579; https://orcid.org/0000-0002-5658-870X; https://orcid.org/0000-0002-1161-3369; https://orcid.org/0000-0002-8767-5021; https://orcid.org/0000-0003-2498-7287; https://orcid.org/0000-0003-3821-412X; https://orcid.org/0000-0002-9635-6313; https://orcid.org/0000-0002-3462-7632; S-6973-2016; ABD-7304-2021; AAJ-7865-2021; AAJ-7201-2021; AAE-1041-2021; AAD-9938-2021; AAG-8233-2020; AAJ-8097-2021Item Results of Biliary Reconstruction Using a Polytetrafluoroethylene Graft in Liver Transplant Patients(2017) Haberal, Mehmet; Soy, Ebru H. Ayvazoglu; Moray, Gokhan; Caliskan, Kenan; Yildirim, Sedat; Torgay, Adnan; 0000-0003-2498-7287; 0000-0002-5735-4315; 0000-0002-0993-9917; 0000-0002-3462-7632; 0000-0002-8767-5021; 0000-0002-6829-3300; 28260438; AAE-1041-2021; AAF-4610-2019; AAC-5566-2019; AAJ-8097-2021; AAJ-7201-2021; AAJ-5221-2021Objectives: Biliary complications after liver transplant are a major concern with their high incidence, the need for repeated and long-term treatment, and their potential effects on graft and patient survival. We report our experience with biliary anastomosis using a spiral polytetrafluoroethylene graft. Materials and Methods: Between December 8, 1988, and July 2016, we performed 538 liver transplant procedures. We used a spiral polytetrafluoroethylene graft for biliary anastomosis in 10 patients: for biliary stricture reconstruction after liver transplant in 4 patients and during the primary liver transplant in 6 patients. Results: Four patients who underwent biliary stricture reconstruction are doing well, with normal liver function. Of the 6 patients who received the graft during primary liver transplant, 2 died from sepsis, although they maintained normal liver function. Of the 4 living patients, 1 had a biliary complication that was reconstructed surgically. The 4 living patients are currently doing well, with normal liver function. Conclusions: Our small series of patients shows that the use of a spiral polytetrafluoroethylene graft is effective at reducing biliary complications in transplant patients.Item Prophylactic Oral Calcium Supplementation Therapy to Prevent Early Post Thyroidectomy Hypocalcemia and Evaluation of Postoperative Parathyroid Hormone Levels to Detect Hypocalcemia: A Prospective Randomized Study(2017) Arer, Ilker Murat; Kus, Murat; Akkapulu, Nezih; Aytac, Huseyin Ozgur; Yabanoglu, Hakan; Caliskan, Kenan; Tarim, Mehmet Akin; 0000-0001-7392-961X; 0000-0003-0268-8999; 0000-0002-3583-9282; 0000-0001-6529-7579; 0000-0002-1161-3369; 0000-0002-8767-5021; 28039060; AAM-8548-2021; AAK-2011-2021; AAJ-7913-2021; AAJ-7870-2021; AAJ-7865-2021; AAJ-7201-2021Background: Postoperative hypocalcemia is the most common complication after total thyroidectomy. Postoperative parathyroid hormone (PTH) measurement is one of the methods to detect or prevent postoperative hypocalcemia. Prophylactic oral calcium supplementation is another method to prevent early postoperative hypocalcemia. The aim of this study is to detect the accurate timing of PTH and evaluate efficacy of routine oral calcium supplementation for postoperative hypocalcemia. Methods: A total of 106 patients were performed total thyroidectomy. Rotuine oral calcium supplementation was given to group 1 and no treatment to group 2 according to randomization. Serum calcium and PTH level of patients in group 2 at postoperative 6, 12 and 24 h and patients in both groups at postoperative day 7 were evaluated. Patients were compared according to age, sex, operation findings, serum calcium and PTH levels and symptomatic hypocalcemia. Results: Half of the patients (50%) were in group 1. Most of the patients were female (83%). The most common etiology of thyroid disease was multinodular goiter (64.1%). Oral calcium supplementation was given to 18 (33.9%) patients in group 2. Symptomatic hypocalcemia for group 1 and 2 was found to be 1.9 and 33.9% respectively (p < 0.05). No statistical difference can be observed regarding the timing of serum biomarkers. Conclusion: Serum PTH levels at postoperative 12 and 24 h can predict early post-thyroidectomy hypocalcemia. Prophylactic oral calcium supplementation therapy can prevent early post-thyroidectomy hypocalcemia with advantages of being cost effective and safe. (C) 2016 IJS Publishing Group Ltd.Item Four-Year Analyses of Renal Graft Biopsies: A Single-Center Pathology Experience(2017) Canpolat, Tuba; Ozdemir, Binnaz Handan; Torun, Dilek; Caliskan, Kenan; Haberal, Mehmet; https://orcid.org/0000-0002-7528-3557; https://orcid.org/0000-0002-6267-3695; https://orcid.org/0000-0002-8767-5021; https://orcid.org/0000-0002-3462-7632; 27099951; AAK-8107-2021; X-8540-2019; AAD-9111-2021; AAJ-7201-2021; AAJ-8097-2021Objectives: Kidney transplant is the best treatment for patients with end-stage renal disease. Long-term graft survival depends on the protection of renal allograft function. Renal allograft biopsy is the most important method for examining an allograft function. Biopsy provides critical information, enabling diagnosis and grading of pathologic changes, prediction of response to therapy, and long-term graft prognosis. Materials and Methods: We reviewed the medical records of patients who underwent renal transplant from living and deceased donors at Baskent University Adana Teaching and Research Hospital between 2010 and 2014 and who had an indication for biopsy. Clinical characteristics and laboratory results of patients were recorded. Patient biopsy samples were examined according to the Banff 2009 classification. Results: Between 2010 and 2014, there were 175 renal transplants performed at our hospital, with 134 recipients (76.6%) having living-donor and 41 recipients (23.4%) having deceased-donor transplants. Fifty-one patients (29.1%) were children, and 124 patients (70.9%) were adults. We found that there were 123 biopsies made from 75 transplant patients over a 4-year period. When examined according to Banff 2009 criteria, the biopsy samples revealed acute T-cell-mediated rejection alone in 14.1% of the samples, acute antibody-mediated rejection in 4%, and a combination of the 2 rejections in 5.7%. Specific infections were detected in 12 patients. The graft nephrectomy rate was 5.1%. Conclusions: This study investigated biopsy results, their relation with patient clinical status and 4-year survival rates, and our pathology experience and found that rejection and infection rates were similar to the literature. Our future studies with a longer follow-up and a larger sample size will likely provide more accurate information about graft survival and biopsy results.Item Investigation of miRNA and Anti HLA Antibodies Correlation in Patients with Kidney Transplant(2018) Basturk, Bilkay; Sozer, Oktay; Kantaroglu, Bircan; Caliskan, Kenan; Torun, Dilek; Noyan, Aytul; Haberal, Mehmet; 0000-0002-8784-1974; 0000-0002-8767-5021; 0000-0002-6267-3695; 0000-0002-3462-7632; AAD-6918-2021; AAJ-7201-2021; AAD-9111-2021; AAD-5713-2021; AAJ-8097-2021Item Cardiac Function in Children After Kidney Transplantation(2018) Arslan, Alev; Parmaksiz, Gonul; Noyan, Aytul; Caliskan, Kenan; Yildirim, Sedat; Haberal, Mehmet; 0000-0003-4444-0027; 0000-0003-2373-1837; 0000-0002-8767-5021; 0000-0002-5735-4315; 0000-0002-3462-7632; V-1112-2019; AAM-2935-2021; AAD-5713-2021; AAJ-7201-2021; AAF-4610-2019; AAJ-8097-2021Item Corner-Saving Renal Artery Anastomosis for Renal Transplantation(2018) Akdur, Aydincan; Kus, Murat; Moray, Gokhan; Yildirim, Sedat; Karakayali, Feza Yarbug; Caliskan, Kenan; Haberal, Mehmet; 0000-0002-8726-3369; 0000-0001-6529-7579; 0000-0003-2498-7287; 0000-0002-5735-4315; 0000-0002-1874-947X; 0000-0002-8767-5021; 0000-0002-3462-7632; AAA-3068-2021; AAJ-7870-2021; AAE-1041-2021; AAF-4610-2019; AAB-3888-2021; AAJ-7201-2021; AAJ-8097-2021
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