Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
Permanent URI for this collectionhttps://hdl.handle.net/11727/1402
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Item Is 25(OH)D Associated with Cognitive Impairment and Functional Improvement in Stroke? A Retrospective Clinical Study(2015) Yalbuzdag, Seniz Akcay; Sarifakioglu, Banu; Afsar, Sevgi Ikbali; Celik, Canan; Can, Asli; Yegin, Tugba; Senturk, Burcu; Guzelant, Aliye Yildirim; 0000-0002-4003-3646; 25922112; E-2103-2019Background: In recent years, vitamin D deficiency has been suggested as a risk factor for ischemic stroke and stroke severity in both animal models and clinical studies. In this retrospective study, we investigated the relationship between 25-hydroxyvitamin D [25(OH)D] levels and functional outcomes in stroke patients during neurological rehabilitation program. We also investigated whether there is an association between 25(OH)D levels and cognitive impairment. Methods: The study included the medical records of 120 stroke patients who participated in a neurological rehabilitation program. The motor and cognitive components of the Functional Independence Measurements of all patients at admission and discharge were recorded. The Functional Ambulatory Scale was used to assess motor functional status, and the Turkish-validated version of the minimental state examination test was used to assess cognitive status. Results: A significant correlation was found between 25(OH)D level and cognitive impairment among patients who had ischemic strokes. High levels of 25(OH)D were associated with greater functional gain during the rehabilitation program in both ischemic stroke patients and hemorrhagic stroke patients. Conclusions: High 25(OH)D levels might be associated with greater functional improvement and with less cognitive impairment in stroke patients.Item The Effects of Exercise Program on Satisfaction Level in Unilateral Above Knee Amputees(2015) Anaforoglu, Bahar; Erbahceci, Fatih; Tuzun, Emine Handan; Sonmezer, EmelPurpose: To investigate the effects of exercise program performed under the supervision of a physiotherapist, on prosthetic satisfaction level in unilateral above knee amputees. Methods: 19 unilateral above knee amputees, with the mean age of 39.3+/-12.8 years were enrolled in this study. The sociodemographic and clinical characteristics and properties of the prostheses of the participants were recorded. All cases attended to a 10 session exercise program. They continued the exercises after the program finished. The satisfaction level of the patients concerning comfort, appearance weight of the prosthesis and walking with prosthesis were assessed by Visual Analog Scale (VAS) before and 2 months after the treatment. Results: When compared pre and post-treatment results, comfort of the prosthesis (p=0.048), satisfaction with the appearence of prosthesis (p=0.01), and walking ability (p=0.033) were statistically different. Discussion: In the present study, it is demonstrated that the exercise program affected prosthetic satisfaction levels positively in unilateral above knee amputees.Item Targeted Treatment Protocol in Patellofemoral Pain: Does Treatment Designed According to Subgroups Improve Clinical Outcomes in Patients Unresponsive to Multimodal Treatment?(2019) Yosmaoglu, Hayri Baran; Selfe, James; Sonmezer, Emel; Sahin, Ilknur Ezgi; Duygu, Senay Cerezci; Ozkoslu, Manolya Acar; Richards, Jim; Jenssen, Jessica; 31750786; AAA-4826-2020Background: Targeted intervention for subgroups is a promising approach for the management of patellofemoral pain. Hypothesis: Treatment designed according to subgroups will improve clinical outcomes in patients unresponsive to multimodal treatment. Study Design: Prospective crossover intervention. Methods: Patients with patellofemoral pain (PFP; n = 61; mean age, 27 +/- 9 years) were enrolled. Patients with PFP received standard multimodal treatment 3 times a week for 6 weeks. Patients not responding to multimodal treatment were then classified into 1 of 3 subgroups (strong, weak and tight, and weak and pronated foot) using 6 simple clinical tests. They were subsequently administered 6 further weeks of targeted intervention, designed according to subgroup characteristics. Visual analog scale (VAS), perception of recovery scale (PRS), 5-Level European Quality 5 Dimensions (EQ-5D-5L), and self-reported version of the Leeds Assessment of Neuropathic Symptoms and Signs scale (S-LANSS) were used to assess pain, knee function, and quality of life before and after the interventions. Results: In total, 34% (n = 21) of patients demonstrated recovery after multimodal treatment. However, over 70% (n = 29/40) of nonresponders demonstrated recovery after targeted treatment. The VAS, PRS, S-LANSS, and EQ-5D-5L scores improved significantly after targeted intervention compared with after multimodal treatment (P < 0.001). The VAS score at rest was significantly lower in the "weak and pronated foot" and the "weak and tight" subgroups (P = 0.011 and P = 0.008, respectively). Posttreatment pain intensity on activity was significantly lower in the "strong" subgroup (P = 0.006). Conclusion: Targeted treatment designed according to subgroup characteristics improves clinical outcomes in patients unresponsive to multimodal treatment.