Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
Permanent URI for this collectionhttps://hdl.handle.net/11727/1402
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Item The Relation Between Meal Frequency and Obesity in Adults(2018) Muftuoglu, Selen; Ozdemir, Merve; Saka, Mendane; Ok, Mehtap Akcil; Koseler, Esra; Bayram, Sinem; Yesil, Esen; Kose, Beril; Turker, Perim; Ercan, Aydan; Aksoydan, Emine; Tayfur, Muhittin; Kiziltan, Gul; 0000-0003-1569-7747; AAF-4491-2021; AAX-4714-2021; AAG-6763-2020; AAZ-8170-2020Objective: To determine the relation between meal frequency and obesity in adults. Methods: A cross-sectional study was done among 1829 volunteer (520 men, 1309 women) selected through a multi-stage stratified random sampling method during 2015/2016. A standardized, confidential data collection sheet was used. It included socio-demographic factors, dietary behaviors, anthropometric measurements and energy-macro and micronutrient intakes. Results: The median meal frequency of women and men were 4 and 3, respectively. Approximately 57% of men and 61% of women have skipped meals and 76.8% of them were skipped their lunch. In addition, the individuals whose BMI were under and over 25 kg/m(2) (72.4%, 78.3%, respectively) often skipped lunch. The meal frequency positively correlated with waist to hip ratio in women (p<0.05). Additionally, there were positively significant correlations between meal frequency and saturated fatty acids, fiber, vitamin A, vitamin C, calcium and iron intake (p<0.05). Conclusion: This study indicated that increased meal frequency may have a beneficial effect on micronutrients intakes and some anthropometric measurements among adults.Item The Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Rats(2018) Koseler, Esra; Kiziltan, Gul; Turker, Perim Fatma; Saka, Mendane; Ok, Mehtap Akcil; Bacanli, Didem; Aydos, Tolga Resat; Bayraktar, Nilufer; Ozdemir, Handan; 0000-0002-4254-3711; 0000-0002-1832-9336; 0000-0002-7886-3688; AAZ-8170-2020; AAJ-7279-2020; Y-8758-2018Objective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.Item The impact of occupational education on obesity prejudice of university students(2021) Ercan, Aydan; Altun, Simay; Ok, Mehtap AkcilObjective: The aim of this study was to investigate the obesity related prejudices and negative attitudes of university students who study in health and non-health fields. Subjective and Methods: This is a descriptive study conducted to determine the obesity prejudice levels of students studying in health and social fields. A total of 732 students (577 females, 155 males) of different faculties of a university participated in the study voluntarily. The Prejudice was measured with Obesity Prejudice Scale (OPS). Analysis of Variance and Covariance were used to investigate relationships between of OPS scores and factors. Results: A total of 732 students, 577 (78.8%) females and 155 (21.2%) males, participated in this study, which was conducted to determine obesity prejudices of university students. According to their mean OPS scores, 18.4% of the students were found to be unprejudiced, 55.1% prone to be prejudiced, and 26.5% prejudiced. The intragroup comparisons of mean OPS scores of health and social field students indicated that the differences between the prejudiced and the unprejudiced were statistically highly significant (p<0.0001). Conclusions: In order to prevent the development of internalized obesity prejudices emerging as a result of prejudices against obese individuals in the society and their stigmatization, this problem must be solved at an early age, especially during university education. It is necessary that state policies should be established to monitor the attitudes of individuals towards obesity, people should be educated and supervised on this subject, and that further research representing the society on this topic should be conducted.Item Triglycerides/high-density lipoprotein cholesterol is a predictor similar to the triglyceride-glucose index for the diagnosis of metabolic syndrome using International Diabetes Federation criteria of insulin resistance in obese adolescents: a cross-sectional study(2020) Cin, Nazli Nur Asian; Yardimci, Hulya; Koc, Nevra; Ucakturk, Seyit Ahmet; Ok, Mehtap Akcil; 32447329; AAZ-8170-2020Objectives: Metabolic syndrome (MS) is a fatal endocrinopathy that begins with insulin resistance (IR) and causes abdominal obesity, glucose intolerance, or systemic disorders. This study was aimed to determine the cut-off values for the triglyceride (TG)/high-density lipoprotein cholesterol (TG/HDL-C) ratio, the TG glucose (TyG) index and homeostasis model assessment (HOMA-IR) for the diagnosis of MS in obese adolescents, and to compare which of the three indexes would offer a more accurate approach to diagnosis. Methods: The study population comprised 1,171 obese adolescents (639 females and 532 males aged 10-16 years, Body Mass Index (BMI)>=95th percentile). Indirect measures of IR screening for MS were the TG/HDL ratio, TyG index, and HOMA-IR. The cut-off values of the TG/HDL ratio, TyG index, and HOMA-IR were obtained from receiver operation characteristic (ROC) curves. Results: HOMA-IR had a significant positive correlation with the TyG index (r=0.352, p<0.001) and TG/HDL-C (r=0.291, p<.001). The TyG index and TG/HDL-C showed a strong positive correlation (r=0.901, p<0.001). The TG/HDL-C ratio showed a larger ROC Area under Curve (AUC=0.849) than HOMA-IR index (AUC=0.689), but as a predictor similar to TyG index (AUC=0.833) when screening for MS. The cut-off values for MS were as follows: TG/HDL-C ratio>2.16 (sensitivity: 88.8%; specificity: 49.7%), TyG index>8.50 (sensitivity: 85.6%; specificity: 57.0%) and HOMA-IR>2.52 (sensitivity: 83.2%; specificity: 40.4%). Conclusions: Both the TyG index and TG/HDL-C ratio are better markers than HOMA-IR to determine the risk of metabolic syndrome according to IDF criteria. Besides, the TyG index and TG/HDL-C ratio have similar differentiating powers to determine this risk in obese Turkish adolescents.Item Effect of weight loss diets on biochemical parameters and anthropometric measurements in prolactinoma patients(2019) Yesil, Esen; Kiziltan, Gul; Anil, Cuneyd; Ok, Mehtap Akcil; Bayraktar, Nilufer; AAZ-8170-2020Background: The aims of this study were to determine the effect of weight loss on biochemical parameters and anthropometric measurements in prolactinoma patients and to evaluate the effectiveness of weight loss diet along with medical treatment. Methods: Twenty-two patients with prolactinoma were divided into two groups and one of the groups was applied weight loss diet (diet group) while the other group was diet free (control group). Each participant was interviewed using a structured questionnaire. The biochemical parameters (fasting plasma glucose, fasting plasma insulin, prolactin, leptin, TSH, T4, cortisol, HbA1c, AST, ALT and blood lipids) of participants were analyzed and anthropometric measurements were taken. Results: There was a significant change in mean BMI after treatment in diet group (p=0.000). The mean level of serum prolactin decreased from 45.1 +/- 31.63 ng/dL at baseline to 12.6 +/- 8.19 ng/dL after three months in diet group (p=0.006). Despite there being no statistically significant difference between diet and control group in terms of baseline level of prolactin measurement (p=0.800), statistically significant difference between the two groups in terms of final level of prolactin measurement (p=0.027) was observed. There was a significant change in mean level of leptin after treatment in diet group (p=0.001). Conclusions: In addition to medical treatment, weight loss diets sped up the healing process for hyperprolactinemia and the reduction in body weight had positive effects on the metabolic profiles of prolactinoma patients.Item The relationship between quality of life and anthropometric measurements in premenopausal and postmenopausal among turkish women(2019) Kose, Beril; Yesil, Esen; Turker, Perim Fatma; Ok, Mehtap Akcil; Bayram, Sinem; Beyaz, Esra Koseler; Ozdemir, Merve; Muftuoglu, Selen; Tayfur, Muhittin; Aksoydan, Emine; Ercan, Aydan; Saka, Mendane; Kiziltan, Gul; 0000-0003-1569-7747; AAG-6763-2020The aim of this work was to investigate whether there is a relationship between anthropometric measurements and quality of life scores during pre and postmenopouse period. A descriptive study was carried out on 1276 women (40-64 years). Demographic features, socioeconomic attributes and anthropometric measurements were considered using a validated instrument the Turkish version of the EUROHIS (WHOQOL-8.Tr) was performed. Significant body mass index (BMI), height, waist circumference, hip circumference, waist/ height ratio differences were determined by comparing pre and postmenopausal women (p <0.05). Significantly lower quality of life scores were observed in premenopausal women (p<0.05). BMI was determined as significant predictor for quality of life for each group. The number of pregnancy, number of live birth, number of stillbirth and waist/height ratio did not show significant association with quality of life. The age of first pregnancy was stated as significant predictor for quality of life just for premenopausal women. In our study, quality of life increased as the BMI decreased in pre and postmenopausal women. Significantly lower WHO-8 EUROHIS scores were observed in premenopausal women. The age of first pregnancy affected the life quality in positive way in just premenopausal women. As the age of first pregnancy increased, quality of life score increased in premenopausal women.