Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
Permanent URI for this collectionhttps://hdl.handle.net/11727/1402
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Item The Relation Between Meal Frequency and Obesity in Adults(2018) Muftuoglu, Selen; Ozdemir, Merve; Saka, Mendane; Ok, Mehtap Akcil; Koseler, Esra; Bayram, Sinem; Yesil, Esen; Kose, Beril; Turker, Perim; Ercan, Aydan; Aksoydan, Emine; Tayfur, Muhittin; Kiziltan, Gul; 0000-0003-1569-7747; AAF-4491-2021; AAX-4714-2021; AAG-6763-2020; AAZ-8170-2020Objective: To determine the relation between meal frequency and obesity in adults. Methods: A cross-sectional study was done among 1829 volunteer (520 men, 1309 women) selected through a multi-stage stratified random sampling method during 2015/2016. A standardized, confidential data collection sheet was used. It included socio-demographic factors, dietary behaviors, anthropometric measurements and energy-macro and micronutrient intakes. Results: The median meal frequency of women and men were 4 and 3, respectively. Approximately 57% of men and 61% of women have skipped meals and 76.8% of them were skipped their lunch. In addition, the individuals whose BMI were under and over 25 kg/m(2) (72.4%, 78.3%, respectively) often skipped lunch. The meal frequency positively correlated with waist to hip ratio in women (p<0.05). Additionally, there were positively significant correlations between meal frequency and saturated fatty acids, fiber, vitamin A, vitamin C, calcium and iron intake (p<0.05). Conclusion: This study indicated that increased meal frequency may have a beneficial effect on micronutrients intakes and some anthropometric measurements among adults.Item The Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Rats(2018) Koseler, Esra; Kiziltan, Gul; Turker, Perim Fatma; Saka, Mendane; Ok, Mehtap Akcil; Bacanli, Didem; Aydos, Tolga Resat; Bayraktar, Nilufer; Ozdemir, Handan; 0000-0002-4254-3711; 0000-0002-1832-9336; 0000-0002-7886-3688; AAZ-8170-2020; AAJ-7279-2020; Y-8758-2018Objective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.Item Effects of reproductive and sociodemographic factors on obesity in Turkish women: a pilot study(2019) Bayram, Sinem; Koseler, Esra; Kiziltan, Gul; Ok, Mebtap Akcil; Yesil, Esen; Kose, Beril; Ozdemir, Merve; Muftuoglu, Selen; Saka, Mendane; Aksoydan, Emine; Tayfur, Muhittin; Turker, Perim Fatma; Ercan, Aydan; 0000-0003-1569-7747; 0000-0002-4254-3711; AAF-4491-2021; AAG-6763-2020Background and aim: Obesity has become a global epidemic. The current research aimed to determine sociodemographic and reproductive predictors of obesity among Turkish women. Materials and methods: Eligible subjects (n:833) were 40-64 years-old women living in Turkey. A questionnaire consisted of questions about sociodemographic and reproductive factors and the International Physical Activity Questionnaire were applied to participants by face to face interviews. Multivariate logistic regression examined the risk of being obese with a range of sociodemographic and reproductive factors. All analyses were performed with SPSS software (version 17.0; SPSS, Chicago, Ill., USA). Results: The mean BMI of women aged 51-64 years was 30.59 +/- 6.35 kg/m(2). After adjustments for all other variables, increased obesity risk remained significant in women who had two children, housewifes, minimum active ones, ex smokers and had less than high school education. For multiple regression analysis sociodemographic factors from the bivariate analyses were entered, controlling for menarch age, menopausal age, hormone RT, parity, number of stillbirth, abortion. There was significant association between family income, occupation, education and BMI. Conclusion. In summary these findings showed comparable patterns of association of sociodemographic and reproductive factors with obesity in Turkey. Specific healthy lifestyle counseling is important for decreasing obesity in childbearing age women.Item Is training for informal caregivers and their older persons helpful? A systematic review(2019) Aksoydana, Emine; Aytar, Aydan; Blazeviciene, Aurelija; van Bruchem-Visser, Rozermarijn L.; Veskelyte, Alina; Mattace-Raso, Francesco; Acar, Sema; Altintas, Atahan; Akgun-Citak, Ebru; Attepe-Ozden, Seda; Baskici, Cigdem; Kava, Sultan; Kiziltan, Gul; 0000-0003-0361-7498; 30953963; ABD-7108-2020; AAI-6607-2020; V-9745-2019Background: The steady increase in the number of people suffering from chronic diseases and increasing life expectancy raises new demands on health care. At the same time, the need for informal caregivers is increasing. This study aims to perform a systematic review of the methodologies used to identify effect of different types of training on informal caregivers and their older persons. Methods: MEDLINE (PubMed), CINAHL and Ovid were searched from December 2016 and April 2017. The following keywords were used; "informal caregiver", "training" "elderly", older persons". Identified publications were screened by using the following inclusion criteria; systematic reviews, randomized controlled trials, prospective cohort and multicentre studies, English language full text journals, samples or interventions that included caregivers of older persons and published in last 10 years. Results: Twenty four studies (12 randomised control trials, 8 intervention studies and 4 systematic reviews) were included. Most of the randomized controlled trials involved both caregivers and elderly. Pretests and post-tests were used in intervention studies (5 out of the 8 studies). ICT-based, psychosocial interventions on family caregivers' education program for caregivers were applied. Caregivers following a supportive educative learning had a significantly better quality of life. Conclusions: The findings of this systematic review suggest that support interventions for caregivers can be effective in reducing caregivers' stress, with a consequent improvement of the quality of care. However, results are based on relatively small studies, reporting somewhat controversial findings supporting the need to perform further research in this field.Item The Effect of Family Participation in Nutrition Education Intervention on the Nutritional Status of Preschool Age Children(2019) Aktac, Sule; Kiziltan, Gul; Avci, SuleymanTo evaluate the effectiveness of family participation in nutrition education intervention on the nutritional status of preschool age children, a 10-week nutrition education program was implemented in 74 children in a public kindergarten. Children were assigned to one of three groups, namely the family participation group (FPG), the education group (EG), and the control group (CG). Interventions included school-based nutrition education, family nutrition education documents and family-child take-home activities and monthly meetings with families in the FPG, school-based nutrition education in the EG, and no intervention in the CG. Anthropometric measurements and a 3-day food record and food group consumption assessment were completed before and after intervention. Intervention led to positive changes in food availability, offering and consumption patterns in FPG and EG, with greater changes in FPG, along with lower obesity prevalence (p < 0.05). Our results show that family participation in a preschool nutrition education program can increase the effectiveness of nutrition education.Item Effect of weight loss diets on biochemical parameters and anthropometric measurements in prolactinoma patients(2019) Yesil, Esen; Kiziltan, Gul; Anil, Cuneyd; Ok, Mehtap Akcil; Bayraktar, Nilufer; AAZ-8170-2020Background: The aims of this study were to determine the effect of weight loss on biochemical parameters and anthropometric measurements in prolactinoma patients and to evaluate the effectiveness of weight loss diet along with medical treatment. Methods: Twenty-two patients with prolactinoma were divided into two groups and one of the groups was applied weight loss diet (diet group) while the other group was diet free (control group). Each participant was interviewed using a structured questionnaire. The biochemical parameters (fasting plasma glucose, fasting plasma insulin, prolactin, leptin, TSH, T4, cortisol, HbA1c, AST, ALT and blood lipids) of participants were analyzed and anthropometric measurements were taken. Results: There was a significant change in mean BMI after treatment in diet group (p=0.000). The mean level of serum prolactin decreased from 45.1 +/- 31.63 ng/dL at baseline to 12.6 +/- 8.19 ng/dL after three months in diet group (p=0.006). Despite there being no statistically significant difference between diet and control group in terms of baseline level of prolactin measurement (p=0.800), statistically significant difference between the two groups in terms of final level of prolactin measurement (p=0.027) was observed. There was a significant change in mean level of leptin after treatment in diet group (p=0.001). Conclusions: In addition to medical treatment, weight loss diets sped up the healing process for hyperprolactinemia and the reduction in body weight had positive effects on the metabolic profiles of prolactinoma patients.Item The effect of nutrition theraphy on oxidative stress, inflammation, glycemic control in type 2 diabetes patients(2019) Colak, Gozde Aritici; Kiziltan, GulAims: Type 2 diabetes mellitus is a metabolism disease which is seen frequently among adult population in Turkey. The aim of this study was to determine the medical nutrition theraphy effect on oxidative stress, inflammation, glycemic control in type 2 diabetes patients. Methods: An interventional study was carried on 35 type 2 diabetes ages between 20-65 years old at the Department of Endocrinology of Baskent University Istanbul Hospital in 2015. In 3 month period a personal nutrition theraphy was applied. Biochemical parameters, anthropometric measurements and body analysis were also determined. The three day food consumption and biochemical parameters were requested at the beginning and at the end of the study. Results: When the impact of the blood values of the new medical nutrition theraphy which the patients practiced during the first visit and the follow up visit were compared; it was seen that there was a significant decrease on fasting plasma glucose, fasting insulin, HbA1c, CRP, TG and MDA values (p<0.05). The mean diabetic age of the patients was 7.63 +/- 6.22 years. When diabetic age of the patients was increased, there was a positive correlation between the fasting plasma glucose and HbA1c values (p<0.05). Conclusions: Type 2 diabetes patients were evaluated 3 month of medical nutrition theraphy and it was seen that the personal medical nutritional theraphy contributed to providing glisemic control and decreasing oxidative stress and inflammation.Item The relationship between quality of life and anthropometric measurements in premenopausal and postmenopausal among turkish women(2019) Kose, Beril; Yesil, Esen; Turker, Perim Fatma; Ok, Mehtap Akcil; Bayram, Sinem; Beyaz, Esra Koseler; Ozdemir, Merve; Muftuoglu, Selen; Tayfur, Muhittin; Aksoydan, Emine; Ercan, Aydan; Saka, Mendane; Kiziltan, Gul; 0000-0003-1569-7747; AAG-6763-2020The aim of this work was to investigate whether there is a relationship between anthropometric measurements and quality of life scores during pre and postmenopouse period. A descriptive study was carried out on 1276 women (40-64 years). Demographic features, socioeconomic attributes and anthropometric measurements were considered using a validated instrument the Turkish version of the EUROHIS (WHOQOL-8.Tr) was performed. Significant body mass index (BMI), height, waist circumference, hip circumference, waist/ height ratio differences were determined by comparing pre and postmenopausal women (p <0.05). Significantly lower quality of life scores were observed in premenopausal women (p<0.05). BMI was determined as significant predictor for quality of life for each group. The number of pregnancy, number of live birth, number of stillbirth and waist/height ratio did not show significant association with quality of life. The age of first pregnancy was stated as significant predictor for quality of life just for premenopausal women. In our study, quality of life increased as the BMI decreased in pre and postmenopausal women. Significantly lower WHO-8 EUROHIS scores were observed in premenopausal women. The age of first pregnancy affected the life quality in positive way in just premenopausal women. As the age of first pregnancy increased, quality of life score increased in premenopausal women.Item Is neck circumference measurement an indicator for abdominal obesity? A pilot study on Turkish Adults(2014) Saka, Mendane; Turker, Perim; Ercan, Aydan; Kiziltan, Gul; Bas, Murat; 25352874Background: Neck circumference (NC) measurement is one of the simple screening measurements which can be used as an index of upper body fat distribution to identify obesity. Objectives: The aim of this study was to determine the relationship between neck circumferences and obesity. Methods: A total 411 volunteer adults participated in this study (174 men, 237 women). A questionnaire which consisted of anthropometric measurements and demographic features was used. Patients with NC >= 37 cm for men and >= 34 cm for women require evaluation of overweight status. Results: The percentages of the men and women with BMI >= 25kg/m(2) were 55.2% and 27.0% respectively and with high neck circumferences were 85.1% and 38.8%, respectively. The percentages of the men and women with high waist circumference were 31.6% and 79.3%, respectively. In both gender there were positive significant correlations between neck circumference, body weight (men, r=0.576; women, r=0.702; p=0.000), waist circumferences (men, r=0.593; women r=0.667; p=0.000), hip circumferences (men, r=0.568; women, r=0.617; p=0.000) and BMI (men, r=0.587; women, r=0.688; p=0.000). Conclusions: This study indicates that NC was associated with body weight, BMI, waist and hip circumferences and waist/hip ratio for men and women. A significant association was found between NC and conventional overweight and obesity indexes. NC was associated with waist/hip ratio for men and women.Item Assessment of Risk Factors of Obesity and Diet on Breast Cancer in Ankara, Turkey(2016) Kiziltan, Gul; Alim, Nural Erzurum; 28083060Objective: To determine the risk factors of obesity and diet on breast cancer in Ankara, Turkey. Methods: A case-controlled study was carried out on newly diagnosed 40 breast cancer patients [patient group (PC)] and 40 volunteer individuals [control group (CG)] with no diagnosis of cancer and history of cancer in the family with similar characteristics to the age and gender-matched patient group between March and July 2016. All the individuals were administered a questionnaire by face-to-face interview method. Results: The mean menarche age, age at first birth and menopause age were 13.0 +/- 1.17, 22.6 +/- 3.78 and 44.33 +/- 2.39 years in PG and 12.3 +/- 0.95, 21.6 +/- 2.99, 46.71 +/- 2.41 years in CG, respectively. The mean BMI values were determined as 28.1 +/- 6.75 kg/m(2) in PG and 30.1 +/- 6.18 kg/m(2) in CG (p>0.05). It was determined that intake of vitamin C and fiber decreases the risk of breast cancer. Also, eating quickly and smoking were risk factors for breast cancer (p<0.05). Conclusion: This study indicated that there are relationships between menarche age, menopause age, and age at first birth, eating quickly, smoking and breast cancer. Conversely, there are significant negative relationships between dietary fiber, vitamin C intake and breast cancer. As a result, it can be said that there is a link between breast cancer and lifestyle factors and a reduction in the risk of developing breast cancer can be achieved through changes in diet, one of the lifestyle factors.