Sağlık Hizmetleri Meslek Yüksekokulu / Vocational School of Health Services

Permanent URI for this collectionhttps://hdl.handle.net/11727/3080

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    Evaluation of Radioactivity Levels and Radiological Hazards of Some Endemic Plants Used as Medicine in Ankara, Turkey
    (2023) Guven, Aysel; Cengiz, Gulcin Bilgici; Caglar, Ilyas; Ates, Simge; 37536028
    In this study, natural radioactivity levels (Ra-226, Th-232, and (4) K) of some medicinal plant samples with known anti-oxidative properties, which are frequently consumed by animals and humans, were obtained from Ankara province and its surroundings (Mamak, Kizilcahamam, Beypazari, Kahramankazan, and Polatli districts) were determined using a thallium-doped sodium iodide NaI(Tl) gamma spectrometry. By using the determined natural radioactivity concentrations in the collected plant samples, the number of radiological doses that people could be exposed by consuming these plants was calculated. As a result of the study, Ra-226, Th-232, and (4) K radioactivity concentration ranges of the plant samples were found be 14.69 +/- 1.27-59.08 +/- 3.12 Bq kg(-1), 1.78 +/- 0.04-50.05 +/- 2.76 Bq kg(-1) and 207.24 +/- 34.09-826.13 +/- 25.40 Bq kg(-1), respectively. The highest Ra-226, Th-232, and (4) K activity concentrations were measured in Astragalus densifolius subsp. ayashensis (Kahramankazan), Astragalus kochakii (Kahramankazan) and Rumex patientia (Patience Dock) (Kahramankazan) plants, respectively. The lowest Ra-226, Th-232 and,(4) K activity concentration plants were determined respectively as Rumex patientia (Mamak), Lavandula angustifolia (Kizilcahamam), and Astragalus acikirensis (Polatli). The establishment and routine repetition of environmental radioactivity monitoring programs in each region are important for human and animal health, and the results of this study gain importance for Ankara and its surroundings in terms of environmental health.
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    The Effect of Thyroid Dysfunction on Nesfatin-1 And Adiponectin Levels in Rats
    (2017) Atici, Emine; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim; Menevse, Esma; 0000-0003-2461-1212; 0000-0002-5477-5667; 0000-0002-6547-4798; 28796641; AAL-5444-2020; ABA-7831-2020; AAG-5865-2019
    Background: Changes in thyroid hormone concentrations may affect adiponectin concentrations through various mechanisms. A molecule released primarily from the fat cells adiposities; adiponectin has important effects on the regulation of body weight. Aim: The present study aimed to explore the effects of experimental thyroid dysfunction and its treatment on nesfatin-1 and adiponectin levels in rats. Methods: The study included 40 adult male Sprague-Dawley rats which were grouped as follows: (1) control; (2) hypothyroidism [hypothyroidism was induced by intraperitoneal injection of 10 mg/kg/day propylthiouracil (PTU) for 3 weeks]; (3) hypothyroidism + thyroxine group [after hypothyroidism was induced by 2-week PTU injection, they were treated with high-dose L-thyroxine (1.5 mg/kg/day) for 1 week]; (4) hyperthyroidism [hyperthyroidism was induced by 3-weeks' thyroxine injection (0.3 mg/kg/day)]; (5) hyperthyroidism + PTU (after hyperthyroidism was induced by 2-weeks' thyroxine injection, the animals were given 10 mg/kg/day PTU for 1 week). Blood samples taken at the end of the study were analyzed to measure nesfatin-1 and adiponectin levels. Results: It was found that nesfatin-1 levels increased in hypothyroidism, while adiponectin levels decreased (p < 0.001). In experimental hyperthyroidism, on the other hand, both nesfatin-1 and adiponectin levels were found significantly elevated (p < 0.001). Conclusion: The results of the study indicate that nesfatin-1 and adiponectin levels were modified considerably in hypo- and hyperthyroidism, whereas with the restoration of the thyroid function, modified hormone levels went back to normal.
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    Co-Culture of Rat Luteal Cells with Islet Cells Enhances Islet Viability and Revascularization
    (2018) Boyuk, Gulbahar; Yigit, A. Arzu; Aydogan, Ilkay; 0000-0001-5837-6877; 30187177; AAD-1857-2020; C-2636-2017
    Islet cell transplantation is a major treatment strategy for type I diabetes, and has proven to be effective for maintaining glucose homeostasis. However, this treatment requires an extended period of immunosuppression to prevent rejection and recurrent transplantation to maintain function. Thus, to enhance the properties of transplanted islet cells, we examined the effect of the co-culture of luteal cells, which secrete progesterone, on islet cell viability, functionality, and revascularization. It was found that islet viability and functionality were higher in the co-cultured group than in single cultures of islets at 48 and 96 h, in parallel with increased progesterone and vascular endothelial growth factor (VEGF) secretion from luteal cells. In the co-culture groups, VEGF levels at 48 and 96 h and CD31 levels at 48 h were significantly higher than those in the islet groups (p < 0.001 and p < 0.05, respectively), and basic fibroblast growth factor (bFGF) levels were increased at 96 h (p < 0.001). Thus, co-culture with luteal cells may increase islet vascularity by enhancing VEGF and bFGF levels for up to 96 h, which could help to markedly increase the pre-transplantation time to allow for effective immunosuppression therapy. This method may also promote islet cell viability and functionality. Progesterone and angiogenic factors secreted from luteal cells may be responsible for these positive effects.
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    Antecedents of Nurse Burnout During a Pandemic: Managerial Way Out
    (2022) Basar, Ufuk; Dogan, Aysun; Ertugrul, Bekir
    The aim of this research is to uncover whether nurses' fear of contracting Coronavirus Disease 2019 (COVID-19) has resulted in stress-related presenteeism and burnout, and whether perceived organisational support is effective in dealing with both nurses' fear of contracting COVID-19 and its undesired consequences. For this purpose, a cross-sectional and descriptive research has been conducted. The data are collected from 513 nurses working in Ankara, Turkey, through a questionnaire survey. Independent samples t-test, one-way analysis of variance test and partial least squares structural equation modelling technique are employed to analyse the data. Findings indicate that nurses fear infection and experience stress-related presenteeism and burnout considerably. However, they perceive slightly inadequate level of organisational support. Fear of infection has resulted in stress-related presenteeism and burnout. Stress-related presenteeism has mediated the relationship between fear of infection and burnout. Perceived organisational support has negatively related to fear of infection and its negative consequences. In this research, to our knowledge, for the first time, the burnout, stress-related presenteeism, fear of infection and perceived organisational support levels of nurses are compared according to the pandemic-related criteria. Besides, the mediating role of nurses' stress-related presenteeism between their fear of contracting COVID-19 and burnout is discovered.
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    Temperature dependence of the piezoelectric resonance frequency in relation to the anomalous strain near the incommensurate phase of quartz
    (2021) Ates, S; Yurtseven, H.
    The temperature dependence of the piezoelectric resonance frequency is analyzed by the power-law formula in the vicinity of the critical temperature of the incommensurate (INC) phase in quartz using the experimental data from the literature. By considering the piezoelectric resonance frequency as an order parameter of the INC phase, correlation between the piezoelectric resonance frequency and the strain is constructed, which both decrease linearly with increasing temperature toward T-c in quartz. Our results can explain dynamics of the ordering mechanism in the INC phase (within a very narrow temperature interval between the alpha and beta phases of quartz) and suggest a second order transition from INC to the beta phase in quartz.
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    Calculation of the damping constant and the relaxation time of the LA mode in the incommensurate phase of quartz
    (2021) Ates, S.; Yurtseven, H.
    The damping constant (linewidth) of the LA mode is calculated as a function of temperature for the incommensurate (INC) phase of quartz by using the models of the pseudospin-phonon (PS) coupled and the energy fluctuation (EF). For this calculation, the observed linewidth (Gamma(LA)) data are used at P = 0 and 80.5MPa from the literature. Close to the incommensurate phase between the alpha and beta phases of quartz, the observed Gamma(LA) and the frequency shifts (Delta v(LA) ) are also analyzed by the power-law formula for both pressures (P = 0 and 80.5MPa). By using the Gamma(LA) and Delta v(LA), the inverse relaxation time (tau(-1)(LA)) is predicted as a function of temperature (P = 0 and 80.5MPa) in the incommensurate phase of quartz and the values of the activation energy (E-a) are deduced. Our calculated Gamma(LA) from both models (PS and EF) explain adequately the observed behavior of the linewidth of the LA mode in the incommensurate phase of quartz. Also, our predicted tau(-1)(LA) can be compared with the measurements in the INC phase of this molecular crystal.
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    Analysis of the IR-Raman Modes and the Heat Capacity Near the alpha-Inc-beta Transitions in Quartz
    (2021) Yurtseven, H.; Gunay, E.; Karacali, H.; Ates, S.
    This study gives our analysis for the temperature dependence of the infrared frequency and the integrated intensity of the 695 cm(-1) mode near the alpha-beta transition at 847.5 K and the temperature dependence of the Raman scattering cross section of the 355 cm(-1) mode near the beta-INC (incommensurate) transition which occurs within a small temperature (similar to 1.3 K) interval in relation to the order parameter in quartz. Both analyses are performed according to a power-law formula for the order parameter Q with the critical index beta using the experimental data from the literature. We also analyze the temperature dependence of the heat capacity C p according to the renormalization-group expression including first-order corrections to scaling term close to the alpha-INC-beta transitions in quartz by using the literature data. From our analyses, values of the critical exponent beta for the frequency and the integrated intensity of the 695 cm(-1) infrared mode and for the Raman scattering cross section of the 355 cm(-1) mode as a measure of the order parameter, are extracted. From the analysis of C p , the values of the critical exponent alpha are also extracted. Additionally, by means of scaling relations the critical exponent gamma of the isothermal compressibility kappa T and the renormalized components ( beta R , alpha R and gamma R ) are predicted for the alpha-INC-beta transitions in quartz. Our analyses given here indicate that weakly first-order transition occurs from the alpha phase to the incommensurate (INC) phase, which changes to the nearly second-order transition to the beta phase with increasing temperature in quartz, as also observed experimentally.
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    Landau phenomenological model for the alpha-INC (incommensurate)-beta transition in quartz
    (2021) Yurtseven, Hamit; Ates, Simge
    The temperature dependence of the order parameters eta (alpha-phase) and xi (INC - incommensurate phase) are calculated in the presence of the electric field for the alpha-INC-beta transition in quartz by the Landau mean field theory. Landau phenomenological model with the linear (eta xi) and quadratic (eta(2)xi(2)) coupling is introduced to investigate mainly the nature of the INC phase between alpha (ordered) and beta (disordered) phases in quartz. The temperature dependence of the inverse susceptibilities (chi(-1h)(eta) and chi(-1)(xi)) of the order parameter is also predicted at constant electric fields studied for the alpha-INC-beta transition in quartz. Additionally, the E-T phase diagram for the transitions of the alpha-INC and INC-beta in quartz is constructed from the Landau phenomenological model by using the literature data. Our predictions for the order parameters (eta and xi) and the inverse susceptibilities (chi(-1)(eta) and chi(-1)(xi)) can be compared with the experimental measurements for the alpha-INC-beta transition in quartz.
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    Effects Of Subscapularis Muscle Soft Tissue Mobilization On Pain And Functionality In Shoulder Dysfunction
    (2021) Gulsen, Mustafa
    Purpose: Tightness of the subscapularis muscle causes glenohumeral external rotation limitation and difficulties in over-head activities. This study aimed to determine the effects of soft tissue mobilization applied to the subscapularis muscle on pain and functionality in shoulder dysfunctions. Methods: The 48 patients with shoulder pain and limitation were included in the study. They were randomly divided into conventional physiotherapy program (CPP) group (n=25) and soft tissue mobilization (STM) group (n=23). The first group received CPP and the second group received STM. All patients had treatment at a physiotherapy clinic for 15 sessions. The pain was evaluated using Visual Analogue Scale (VAS), shoulder joint movements were measured using a goniometer and overhead reach test, and functionality was evaluated using the Shoulder Pain and Disability Index (SPADI). The patients were assessed before, immediately after, and three weeks after the treatment. Results: Statistically significant improvements were found in VAS, shoulder flexion and extemal rotation range of motion, and overhead reach test in both groups immediately after treatment and at the end of the 3rd week (p<0.05). When groups were compared after three weeks, statistically significant improvements were found in VAS, external rotation range of motion, and overhead reach test in the STM group (p<0.05). There was a statistically significant improvement in SPADI in both groups after the treatment (p<0.05). There was no significant difference in SPADI score between the groups (p>0.05). Conclusion: The STM was more effective on pain, range of motion, and functionality than CPP. STM of subscapularis muscle might be an alternative treatment of the shoulder dysfunction.
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    Landau mean-field model with the cubic term for the alpha-beta transition in quartz
    (2020) Ates, S.; Yurtseven, H.
    Thermodynamic quantities are calculated as a function of temperature by using Landau mean-field model for the alpha-beta transition in quartz. By expanding the Gibbs free energy in terms of the order parameter (Q) with the cubic term (Q(3)), the temperature dependence of the relevant thermodynamic quantities are predicted using the heat capacity (C-P), which is fitted to the experimental data from the literature for the alpha-beta transition in quartz. Our results indicate that the Landau mean-field model is adequate to describe the first-order alpha-beta transition in quartz.