Diş Hekimliği Fakültesi / Faculty of Dentistry
Permanent URI for this collectionhttps://hdl.handle.net/11727/2120
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Item Effect of the COVID-19 Pandemic on Anxiety in Patients with Masticatory Muscle Pain(2023) Arifagaoglu, Ozge; Secgin, Cansu Koseoglu; Yuzugullu, Bulem; 0000-0001-9816-2486; 34702584; GRR-7726-2022Statement of problem. Although psychological disorders have been established as one of the etiological factors for temporomandibular disorders, anxiety levels in individuals with masticatory muscle pain before and during the coronavirus 2019 (COVID-19) pandemic have not previously been compared.Purpose. The purpose of this clinical study was to evaluate anxiety levels in patients with masticatory muscle pain at times before and during the COVID-19 pandemic.Material and methods. Eighty patients (18 to 68 years) with masticatory muscle pain were included in the study. All participants had completed the Generalized Anxiety Disorder 7 questionnaire (GAD-7) before the first COVID-19 infection had been reported in Turkey. After the onset of the COVID-19 pandemic, all participants were contacted by telephone to repeat the GAD-7 to evaluate changes in their psychology during the first lockdown. However, 18 of the 80 patients were unreachable. A statistical analysis was performed by using the Mann-Whitney U test. Proportion comparisons between sociodemographic characteristics and GAD-7 levels were performed by using the Fisher exact test (a=.05).Results. Forty-eight (60%) of the study population were women, and 32 (40%) were men, with a mean age & PLUSMN;standard deviation of 36.63 & PLUSMN;13.85 years. Both before and during the pandemic, GAD-7 scores were statistically similar as was each demographic parameter, including sex, educational status, and occupational status (P>.05). Also, no significant correlation was recorded between age and GAD-7 global scores obtained before and during the pandemic (r=-0.098 and r=-0.052, respectively, P>.05). However, during-pandemic GAD-7 scores were statistically higher than before-pandemic GAD-7 scores (P<.001).Conclusions. Demographic parameters had no connection with anxiety levels in patients with masticatory muscle pain before and during the COVID-19 pandemic. However, the COVID-19 pandemic anxiety levels in the participants were higher than the levels before the pandemic. (J Prosthet Dent 2023;130:74-9)Item The Effects of Vaccines on the Sequelae Rates of Recurrent Infections and the Severity of Pulmonary COVID-19 Infection by Imaging(2023) Bahadir, Suzan; Kabacaoglu, Ebru; Memis, Kemal Bugra; Hasan, Hasan Ilksen; Aydin, Sonay; 37631888Although vaccines have been shown to reduce the number of COVID-19 infection cases significantly, vaccine-related reactions, long COVID-19 syndrome, and COVID-19 infection following vaccination continue to be a burden on healthcare services and warrant further scientific research. The purpose of this study was to research the severity of pulmonary COVID-19 infection following vaccination and the sequelae rates of recurrent infections in vaccinated cases by imaging. Patients who underwent follow-up CTs at 1 month, 3 months, and 6 months in our hospital with a diagnosis of COVID-19 were scanned retrospectively. Furthermore, all essential information was gathered from patients' immunization records. The major findings of our study were: (1) sequelae were frequently observed in unvaccinated cases; (2) the correlation between vaccination status and the severity of sequelae was significant; (3) there was not any significant relationship between the vaccine type and the severity of sequelae; and (4) hematocrit, hemoglobin, and lymphocyte parameters may be used as predictors of sequelae rates. COVID-19 infection, although reduced in prevalence following the development of vaccines, still remains a public health concern because of reinfection. Vaccination not only appears to protect against primary infection, but also seems to reduce reinfection and sequalae rates following reinfection.Item Machine Learning Based Orthodontic Treatment Planning for Mixed Dentition Borderline Cases Suffering from Moderate to Severe Crowding: An Experimental Research Study(2023) Senirkentli, G. Burcu; Bingol, Sinem Ince; Unal, Metehan; Bostanci, Erkan; Guzel, Mehmet Serdar; Acici, Koray; 36970921BACKGROUND: Pedodontists and general practitioners may need support in planning the early orthodontic treatment of patients with mixed dentition, especially in borderline cases. The use of machine learning algorithms is required to be able to consistently make treatment decisions for such cases. OBJECTIVE: This study aimed to use machine learning algorithms to facilitate the process of deciding whether to choose serial extraction or expansion of maxillary and mandibular dental arches for early treatment of borderline patients suffering from moderate to severe crowding. METHODS: The dataset of 116 patients who were previously treated by senior orthodontists and divided into two groups according to their treatment modalities were examined. Machine Learning algorithms including Multilayer Perceptron, Linear Logistic Regression, k-nearest Neighbors, Naive Bayes, and Random Forest were trained on this dataset. Several metrics were used for the evaluation of accuracy, precision, recall, and kappa statistic. RESULTS: The most important 12 features were determined with the feature selection algorithm. While all algorithms achieved over 90% accuracy, Random Forest yielded 95% accuracy, with high reliability values (kappa = 0.90). CONCLUSION: The employment of machine learning methods for the treatment decision with or without extraction in the early treatment of patients in the mixed dentition can be particularly useful for pedodontists and general practitioners.Item Influence of the Implant Scan Body Modifications on Trueness of Digital Impressions(2023) Uzel, Sema Merve; Guncu, Mustafa Baris; Aktas, Guliz; Arikan, Hale; Reiss, Natalia; Turkyilmaz, Ilser; 37799878; JXY-2357-2024Background/purpose: Effects of implant angulation on digital impression accuracy remain controversial. The purpose of this study was to assess the relationship between the alteration of implant scan bodies and the trueness of digital impressions. Materials and methods: A maxillary typodont without the right premolars and first molar was scanned with a laboratory scanner and saved as a standard triangular language (STL) file. A model from the STL file was fabricated with a 3-dimensional printer. Two implants were placed into the first premolar and first molar sites of the model, followed by the insertion of two scan bodies onto the implants. These scan bodies were divided into four test groups, based on the surface modifications. A digital impression of each typodont was made with three different intraoral scanners. An abutment was digitally seated on each implant. 120 STL files (30 for each group) of the typodont with two implants and two corresponding abutments were used for statistical analysis. Results: A total of 240 values (two implants for each typodont) were obtained after each sample (4 groups) was scanned 10 times by utilizing three intraoral scanners. The overall linear and angular discrepancies were analyzed. Group 1 showed the lowest linear discrepancy of 14.9 +/- 5.4 mm while Group 4 reported the highest linear discrepancy of 137.5 +/- 41.7 mm, yielding a statistical significance (P < 0.05). Conclusion: It has been concluded that the more adjustments made to the scan bodies, the greater the linear and angular deviations occur, compromising the trueness of the digital implant impression. (c) 2023 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/).Item Systemic Inflammation Score for Predicting Radiation-Induced Trismus and Osteoradionecrosis of the Jaw Rates in Locally Advanced Nasopharyngeal Carcinoma Patients(2023) Somay, Efsun; Sezen, Duygu; Selek, Ugur; Besen, Ali Ayberk; Mertsoylu, Huseyin; Topkan, Erkan; 0000-0001-8120-7123; AAG-2213-2021We sought to determine the predictive value of the systemic inflammation score (SIS) for radiation-induced trismus (RIT) and osteora-dionecrosis of the jaw (ORNJ) in locally advanced nasopharyngeal carcinoma (LA-NPC) patients treated with concurrent chemoradio-therapy (C-CRT). LA-NPC patients (n= 188) who underwent C-CRT and pre-and post-C-CRT oral examinations from August 2010 to January 2022 were included. The three-tiered SIS groups were created using the serum albumin and lymphocyte-to-monocyte ratio (LMR) measures obtained on the first day of C-CRT: SIS-0: Albumin >= 40 g/dL and LMR >= 4.44); SIS-1: Albumin < 40 g/dL and LMR < 4.44 or albumin >= 0 g/dL and LMR >= 4.44; and SIS-2: Albumin < 40 g/dL and LMR <4.44. The primary objective was to ascertain whether there were irrefutable associations between pretreatment SIS groups and the respective post-C-CRT RIT and ORNJ rates. RIT and ORNJ were diagnosed in 33 (17.6%) and 21 (11.1%) patients, respectively. There were 12 (32.4%), 13 (12.7%), and 18 (45.0%) cases diagnosed with RIT in the respective SIS-0, SIS-1, and SIS-2 groups (p< 0.001). Similarly, there were 1 (2.7%), 11 (9.9%), and 9 (22.5%) cases with ORNJ diagnoses in the corresponding SIS groups (p< 0.001). The multivariate analysis's findings revealed that the SIS grouping was an independent predictor of RIT (p< 0.001) and ORNJ incidence rates (p< 0.001). Our study's findings indicate that the novel pretreatment SIS grouping is a dependable biomarker-based system, which can accurately predict the rates of RIT and ORNJ in LA-NPC patients who receive definitive C-CRT.Item Effect of A Calcium Phosphate-Containing Desensitizing Agent on Postoperative Sensitivity: A Split-Mouth, Randomized Controlled Study(2023) Kerimova Kose, Leyla; Yilmaz, Ayfer Ezgi; Yamanel, Kivanc; Arhun, Neslihan; 37865810Purpose: To evaluate the effectiveness of a calcium phosphate-containing-desensitizer (Teethmate Desensitizer - TD), caries type, subject age, and preoperative hypersensitivity on postoperative sensitivity (POS) after composite restorations on deep or extremely deep lesions. Methods: 50 subjects, having two teeth with deep or extremely deep caries, participated in this study. TD was applied randomly to one tooth of each participant, and all teeth were restored with composite resin (Filtek Z250). After 1 week, POS was evaluated according to NRS (numerical rating scale) and VAS (visual analogue scale) by using participant diaries. At 6 weeks, POS was assessed considering subjects' reports. The normality of data was analyzed with Shapiro-Wilk test. For analyses, Pearson's chi-squared test, Mann-Whitney U and the Wilcoxon Signed-Rank test were used, and the effect sizes (ES) were calculated (alpha= 0.05). Results: 47 of the participants completed the 6-week study. There was a small effect size noted for TD for NRS and VAS (P> 0.05, ES < 0.30). Also, there was no statistically significant difference between POS and subject age (P= 0.294, ES= 0.161), type of caries (P= 0.680, ES= 0.042) and preoperative sensitivity (P= 1.000, ES= 0.138) after the first week.Item Survival of Root Canal-Treated Teeth Adjacent to An Implant: A Retrospective Case-Control Study(2023) Sisli, S. N.; Gul Ates, E.; Ozcelik, T. B.; Yilmaz, B.; Revilla Leon, M.; 0000-0001-5685-4409; 0000-0002-6166-2601; 37839623; JJF-5618-2023Objectives: To evaluate the survival of root canal treated (RCT) teeth adjacent to an implant compared with that of RCT teeth of the same patient non-adjacent to an implant.Materials and methods: RCT tooth of each patient adjacent to an implant were included in the test group. The control group consisted of another RCT tooth of the same patient; the control RCT tooth was not adjacent to an implant and selected to be of the same type of the RCT tooth in the test group. 72 teeth of 36 patients with at least 4-year follow-up were included. In addition to survival, other clinical and demographic parameters investigated were age, sex, tooth type and position, presence of a crown, presence of retreatment, presence of a post-core, presence of adjacent edentulous area, presence of implant-supported fixed prosthetic restoration on the antagonist tooth and periapical health status. Pearson Chi-Square and Fisher Exact tests were used to compare the test and the control groups with categorical variables (alpha=0.05). Survival curves were obtained by the Kaplan-Meier method, and the Log-rank test was performed to compare the survival probabilities (alpha=0.05).Results: No significant difference in survival rates was observed between the test and the control groups (p = 0.72). Similarly, no significant relationship was found between the investigated clinical variables and the survival rates of RCT teeth (p>0.05). Survival times differed depending on the presence of an adjacent edentulous area (p<0.001) and the periapical health status (p = 0.026).Conclusions: RCT teeth with unhealed periapical tissues had a shorter cumulative survival time. Similarly, those adjacent to an edentulous area had shorter cumulative and complication-free survival times.Clinical Significance: This is the first study to determine the survival outcome of a RCT tooth adjacent to an implant compared to a non-adjacent one in the same patient. Being adjacent to an implant did not have a detrimental effect on the survival time and rate of RCT teeth.Item Comparison of Implant Survival Rates and Biologic and Mechanical Complications with Implant-Supported Fixed Complete Dental Prostheses Using Four and Six Implants(2023) Tamer, Yusuf; Ozcan, Isil; 37552199This study aims to compare the incidence of biologic and mechanical complication rates and the survival rates after at least 5 years of implants and implant-supported fixed complete dental prostheses (IFCDPs) placed during second-stage surgery using four and six implants. A total of 77 patients (33 men, 44 women) with a mean age of 60.6 +/- 8.8 years (range: 39 to 80 years) were included, and the total of 92 IFCDPs were classified into two groups: 51 received four implants, and 41 received six implants. No implant failed in the four-implant group (0/204), and one implant failed in the six-implant group (1/246), with no statistically significant differences (P > .05). One prosthetic failure occurred in the four-implant group (1/51), and one failure occurred in the six-implant group (1/41). Both groups experienced some technical and biologic complications, with no statistically significant differences between the groups (P > .05). For both groups, veneer or resin fracture was the most frequent mechanical complication, and mucositis was the most frequent biologic complication. The use of four or six implants may represent a predictable treatment option in the rehabilitation of completely edentulous patients with IFCDPs in the medium-term. Int J Periodontics Restorative Dent 2023;43:e157-e163. doi: 10.11607/prd.5997Item Prosthetic Complications with Mandibular Bar-Retained Implant Overdentures Having Distal Attachments and Metal Frameworks: A 2-To 12-Year Retrospective Analysis(2023) Ciftci, Gozde; Somay, Suphi Deniz; Ozcan, Isil; Ozcelik, Tuncer Burak; Yilmaz, Burak; 0000-0001-5685-4409; 34998584; JJF-5618-2023Statement of problem. Long-term reports on 2-implant-retained overdentures having metal frameworks and bars containing distal attachments are scarce.Purpose. The purpose of this retrospective study was to evaluate prosthetic complications with 2-implant-retained mandibular overdentures with metal frameworks having either screw-or cement-retained cantilevered bars with distal attachments.Material and methods. Seventy-three edentulous study participants who had been treated with mandibular overdentures with 2 implants were included. The parameters assessed were acrylic resin fractures (base fracture, fracture at midline), debonding of teeth, opposing prosthesis fracture, need for relining or rebasing, abutment and bar screw loosening and fracture, ball or bar attachment or clip wear, fracture or detachment, bar fracture, and implant loss. Statistical analysis was performed by using the Mann-Whitney U test as the data were not normally distributed. The categorical variables between the groups were analyzed by using the Fisher exact test (alpha=.05).Results. Twenty-seven prostheses had a cement-retained bar, and 46 bars were screw-retained. Of 73 overdentures, 68 were metal-reinforced. The mean observation time was 5.9 years with a range between 2 and 12 years. The most common complication was wear of the Rhein 83 polymer attachment followed by bar screw loosening. The cumulative survival rate for overdentures was 91.9% at 6.8 years. The service life of cement-retained prostheses was significantly longer (P<.05). Bar, resin base, and mid-line fractures were only seen with cement-retained prostheses. The number of times an attachment change was required did not differ between cement-and screw-retained bars. Of 191 implants, 3 were lost, and the cumulative survival rate was 93.5% at 7.5 years. No significant difference was found between retention types in terms of implant loss (P>.05).Conclusions. Based on the participant population observed, the survival rates of 2-implant-retained mandibular overdentures and their implants in the medium term were high. Wear of the polymer attachment was commonly seen. Overdentures with cement-retained bars had bar or acrylic resin fractures. Mandibular 2-implant-retained overdentures with a screw-retained bar containing bilateral distal attachments had fewer prosthetic complications and high implant survival in the medium term.Item Effect of Chitosan and EDTA Solutions on Bond Strength of Two Different Calcium Silicate Based Materials(2023) Koc, Cemre; Gulsahi, Kamran; Kahya, Naime DidemObjective: The aim of the present study was to evaluate the potential of using chitosan-based chelating agents to improve the bond strength of mineral trioxide aggregate (MTA) Angelus (Londrina, PR, Brazil) or MTA Repair high plasticity (Londrina, PR, Brazil). Materials and Methods: A total of 60 dentine discs were obtained from 15 freshly extracted human maxillary central incisors. Two canal -like holes were drilled and the disks were divided into four groups, as following; group 1: chitosan solution with acetic acid; group 2: chitosan solution with lactic acid; group 3: 17% ethylenediaminetetraacetic acid; and group 4: distilled water. Discs were subjected to the tested chelating solution for smear layer removal for 3 min. The two holes of the same dentine discs were each randomly filled with one of the tested materials. The push -out test was performed and data were analyzed using 2 -way analysis of variance test with a 5% significance level. Results: No significant differences were observed for the type of tested material (p=0.153) and the interaction between tested material and solution (p=0.922); however, there was a significant difference among chelating agents (p=0.001). Conclusion: Both materials showed similar bond strength regardless of the a chelating agent was used or not. All chelating agents significantly decreased the push -out strength of both materials, except for the chitosan solution prepared with acetic acid.