Diş Hekimliği Fakültesi / Faculty of Dentistry
Permanent URI for this collectionhttps://hdl.handle.net/11727/2120
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Item Comment on: Intensity Modulated Radiotherapy in Head and Neck Cancer: Initial Experience of the First Treated Cases from North-East India(2023) Topkan, Erkan; Somay, Efsun; Selek, Ugur; 0000-0001-8251-6913; 38187854; AAG-2213-2021; O-5474-2014Item In reply to Cheng et al. (DOI: 10.1186/s13550-023-00965-8)(2023) Somay, Efsun; Topkan, Erkan; Pehlivan, Berrin; Selek, Ugur; 0000-0001-8251-6913; 0000-0001-8120-7123; 37589948; AAG-2213-2021Item Letter to the Editor Regarding "Long-Term Swallow Outcomes and Factors Affecting Swallowing Dysfunction and Quality of Life Among Oral Cancer Patients: A Prospective Observational Study" by Thaduri Et Al. Eur Arch Otorhinolaryngol. 2023 Aug 7. Doi: 10.1007/S00405-023-08155-X(2023) Topkan, Erkan; Somay, Efsun; Selek, Ugur; 37594546; O-5474-2014; AAG-2213-2021Item Comment on: Quality of Life After Segmental Mandibulectomy and Free Flap for Mandibular Osteonecrosis: Systematic Review(2023) Topkan, Erkan; Somay, Efsun; 0000-0001-8251-6913; 37459741; AAG-2213-2021Item Systemic Inflammation Score for Predicting Radiation-Induced Trismus and Osteoradionecrosis of the Jaw Rates in Locally Advanced Nasopharyngeal Carcinoma Patients(2023) Somay, Efsun; Sezen, Duygu; Selek, Ugur; Besen, Ali Ayberk; Mertsoylu, Huseyin; Topkan, Erkan; 0000-0001-8120-7123; AAG-2213-2021We sought to determine the predictive value of the systemic inflammation score (SIS) for radiation-induced trismus (RIT) and osteora-dionecrosis of the jaw (ORNJ) in locally advanced nasopharyngeal carcinoma (LA-NPC) patients treated with concurrent chemoradio-therapy (C-CRT). LA-NPC patients (n= 188) who underwent C-CRT and pre-and post-C-CRT oral examinations from August 2010 to January 2022 were included. The three-tiered SIS groups were created using the serum albumin and lymphocyte-to-monocyte ratio (LMR) measures obtained on the first day of C-CRT: SIS-0: Albumin >= 40 g/dL and LMR >= 4.44); SIS-1: Albumin < 40 g/dL and LMR < 4.44 or albumin >= 0 g/dL and LMR >= 4.44; and SIS-2: Albumin < 40 g/dL and LMR <4.44. The primary objective was to ascertain whether there were irrefutable associations between pretreatment SIS groups and the respective post-C-CRT RIT and ORNJ rates. RIT and ORNJ were diagnosed in 33 (17.6%) and 21 (11.1%) patients, respectively. There were 12 (32.4%), 13 (12.7%), and 18 (45.0%) cases diagnosed with RIT in the respective SIS-0, SIS-1, and SIS-2 groups (p< 0.001). Similarly, there were 1 (2.7%), 11 (9.9%), and 9 (22.5%) cases with ORNJ diagnoses in the corresponding SIS groups (p< 0.001). The multivariate analysis's findings revealed that the SIS grouping was an independent predictor of RIT (p< 0.001) and ORNJ incidence rates (p< 0.001). Our study's findings indicate that the novel pretreatment SIS grouping is a dependable biomarker-based system, which can accurately predict the rates of RIT and ORNJ in LA-NPC patients who receive definitive C-CRT.Item In Reply to Bertl et al.(2023) Somay, Efsun; Topkan, Erkan; Selek, Ugur; 0000-0001-8087-3140; 0000-0001-8120-7123; 0000-0001-8251-6913; O-5474-2014; AAG-2213-2021Item Radiation Therapy for Ct1-2 Carcinoma of the Palatine Tonsil Diagnosed Via A Simple Tonsillectomy: Dosimetry and Patterns of Care in the IMRT Era(2023) Topkan, Erkan; Somay, Efsun; Yilmaz, Busra; 0000-0001-8120-7123; 37804565; AAG-2213-2021Item Response to Outcomes of Immediate Dental Implants in Vascularised Bone Flaps for Mandibular Reconstruction(2023) Somay, Efsun; Topkan, Erkan; 0000-0001-8120-7123; 0000-0001-8251-6913; 37565638; AAG-2213-2021Item Predictive Value of Health-Related Quality of Life on Radiotherapy-Related Toxicities in Patients with Head and Neck Cancer(2023) Somay, Efsun; Topkan, Erkan; Selek, Ugur; 0000-0001-8120-7123; 0000-0001-8087-3140; 0000-0001-8251-6913; 37874385; AAG-2213-2021; O-5474-2014Item Letter to The Editor: To Extract or Not Extract Teeth Prior to Head and Neck Radiotherapy?(2023) Yilmaz, Busra; Somay, Efsun; Topkan, Erkan; https://orcid.org/0000-0003-0633-5648; https://orcid.org/0000-0001-8251-6913; https://orcid.org/0000-0001-8120-7123; 36576606; AAR-6904-2020; AAG-2213-2021