PubMed İndeksli Açık & Kapalı Erişimli Yayınlar
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Item About Assessment of Carotid Artery Calcifications on Radiographs Response(2022) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Yilmaz, Mediha Nur Nisanci; Secgin, Cansu Koseoglu; 35131087; AAC-5931-2020Item Evaluating the Impacts of Some Etiologically Relevant Factors on Excessive Gingival Display(2021) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Akinci, Seray; Bakirarar, Batuhan; 33819318The literature offers limited and even conflicting information on the etiology of gummy smile. Therefore, this study aimed to evaluate smile line, hypermobile upper lip (HUL), altered passive eruption (APE), and short upper lip (SUL) distribution in a group of patients seeking dental treatment and to examine their effects on gummy smile. A total of 501 individuals (265 men, 236 women) were included in the study. The patients were grouped by gingival display, and presence of HUL, APE, and SUL were evaluated. Multivariate Logistic Regression analyses were performed to investigate the impact of possible risk factors on gummy smile. Of the individuals, 173 (34.5%) had a low smile line, 127 (25.3%) had an average smile line, 146 (29.1%) had a high smile line, and 55 (10.9%) were gummy smile patients. Individuals with gummy smile were younger than the individuals with low smile line (P < .001). As for the possible risk factors for gummy smile, age (odds ratio [OR]: 0.936; 95% CI: 0.901 to 0.972; P = .001), HUL (OR: 18.85; 95% CI: 7.82 to 45.44; P < .001), and APE (OR: 8.819; 95% CI: 3.894 to 19.973; P < .001) were found to be significant together. Gender and SUL/upper lip length were not found to have any impact on gummy smile. HUL is the primary factor that increases the probability of having gummy smile, followed by APE as the secondary factor. It seems reasonable to focus on correction of the HUL for treatment in most gummy smile patients.Item The relationship between body mass index and stage/grade of periodontitis: a retrospective study(2021) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Onder, Canan; Bakirarar, Batuhan; 34709456Objectives Possible impact of obesity on stage and grade of periodontitis has never been investigated before. This study aimed to examine the association between body mass index (BMI) and stage/grade of periodontitis per the current classification of periodontal diseases. Material and methods A total of 142 patients (82 males/60 females) were included in this study. "2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions" was taken as basis to characterize the stage/grade of periodontitis. Age, gender, smoking status, and frequency of tooth brushing, and medical data of the patients including hypertension, hyperlipidemia, BMI, and diabetes mellitus were obtained from the patient's hospital records. Obesity was assessed by BMI using the "World Health Organization" criteria. For estimating the association between BMI and periodontitis, logistic regression analysis was utilized. Results BMI was statistically associated with clinical attachment loss (CAL), probing pocket depth (PPD), Plaque index (PI), stage and grade of periodontitis, and number of remaining teeth (p < 0.001, p < 0.05, p < 0.05, p < 0.05, p < 0.001, respectively). According to the multiple regression analysis results, those with BMI 25-29.9 were found to be at risk of being stage III-IV 3.977 times (95% CI: 1.831-8.640, p < 0.001) higher than those with BMI < 25, and similarly, those with BMI >= 30 were found to be at risk of being stage III-IV 4.062 times (95% CI: 1.315-12.549, p = 0.015) higher than those with BMI < 25. No relationship was found between obesity and grade of periodontitis according to multivariate analysis. Conclusions BMI increases the likelihood of stage III and stage IV periodontitis; however, it does not have an impact on the grade of periodontitis.Item Assessment of carotid artery calcifications on digital panoramic radiographs and their relationship with periodontal condition and cardiovascular risk factors(2020) Bilgin Cetin, Mehtap; Sezgin, Yasemin; Nisanci Yilmaz, Mediha Nur; Koseoglu Secgin, Cansu; 32996164Objective The main purpose of this study is to determine the presence of carotid artery calcification (CAC) detected on digital panoramic radiographs (DPRs) retrospectively and correlate the findings with cardiovascular risk factors including gender, age, smoking status, hypertension, diabetes, and hyperlipidemia, along with atherosclerotic cardiovascular disease and periodontal status. Methods This clinical study is registered at ClinicalTrials.gov as NCT04017078. DPRs, periodontal status and cardiovascular risk factors of 1,101 patients (576 males, 525 females) were evaluated. The patients were grouped based on whether CAC was detected in dental DPRs [CAC (+)] or not [CAC (-)]. Periodontal status was categorised as gingivitis, periodontitis, and gingivitis with reduced periodontium (periodontally stable patient). Results Out of 1,101 patients, whose mean age was 42.1 +/- 15.5 years and 525 (47.7%) were female, 34 (3.1%) were diagnosed with CAC on DPRs. No significant difference was observed between groups considering gender, hypertension, diabetes, hyperlipidemia, smoking, and periodontal status. Patients aged 40-55 years (n = 398, 36.15%) and patients older than 55 years (n = 222, 20.16%) were associated with CAC (odds ratio = 4.49, 95% confidence interval = 1.65-12.17,P = 0.003; odds ratio = 4.41, 95% confidence interval = 1.33-14.61,P = 0.015, respectively). Conclusion Among all parameters, only age exhibited significant correlation with an increased risk of carotid calcification. Further studies with prospective designs and larger study populations are needed.Item Association of probable bruxism with periodontal status: A cross-sectional study in patients seeking periodontal care(2020) Cetin, Metin Bilgin; Sezgin, Yasemin; Maras, Enes; Cebeci, Ilker Ata; 0000-0002-5153-2635; 33368265Objective The goals of this study were to investigate the prevalence of probable bruxism in a group of patients seeking a periodontal care and the association between probable bruxism and periodontal status. Background The results of previous studies evaluating the relationship between bruxism and periodontitis are contradictory. In addition, the relationship between probable bruxism and periodontitis in adults has not been evaluated, yet. Therefore, new studies are required in this field to clarify the relationship between bruxism and periodontitis. Methods Patients seeking periodontal care at a university periodontology unit were considered in this study. Their periodontal diagnosis, number of missing teeth, presence of probable bruxism, and sociodemographic characteristics were recorded. The periodontal status of each study participant was defined according to the latest consensus of the American Association of Periodontology/European Federation of Periodontology, and the 2018 consensus report on the assessment of bruxism was used to evaluate probable bruxism. A multiple logistic regression analysis was performed to determine the effects of bruxism on periodontitis. Results A total of 541 patients (289 females and 252 males, mean age 42.1 +/- 15.9 years) were enrolled in the present study. The prevalence of probable bruxism was 36.6%. Additionally, 40.9% of the study population was diagnosed with periodontitis. The probable bruxers were older (P < 0.001), had a higher number of missing teeth (P < 0.001), and had poor periodontal status (P < 0.001). The multivariate logistic regression analysis suggested that probable bruxism was associated with periodontitis, after adjusting relevant factors (odds ratio: 2.243, 95% CI: 1.465-3.434, P < 0.001). Conclusions It was observed that the prevalence of probable bruxism was 36.6% and probable bruxers showed higher odds of periodontitis. Future studies with prospective randomized design should be conducted to confirm these results among a larger study population.Item Evaluating the Effects of a Topical Preparation with Dexpanthenol, Silbiol, Undecylenic Acid, and Lidocaine on Palatal Mucosa Wound Healing in a Rat Model(2019) Sezgin, Yasemin; Cetin, Mehtap Bilgin; Bulut, Sule; Alptekin, Nilgun Ozlem; Borcek, Pelin; 0000-0003-4104-6462; 30322831; G-1816-2014; AAC-5448-2020; AAC-5931-2020Background: Postoperative complications occur after periodontal plastic surgeries, but an ideal treatment to overcome them has not been found yet. Aims: To evaluate the effects of topically applied Oral-norm gel on the healing of excisional wounds. Study Design: Animal experiment. Methods: Excisional wounds with a diameter of 3 mm were made in the center of the palatal mucosa of 63 Sprague Dawley rats. Seven animals were sacrificed at time 0. The remaining rats were divided into two groups: a test group in which the topical Oral-norm gel was applied three times a day and a control group in which nothing was applied. Seven animals in each group were sacrificed at 3, 7, 14, and 21 days. Mean wound surface area was measured photographically, while wound healing and width were evaluated microscopically. Results: The mean wound surface area decreased significantly after 3 days in both groups (p<0.001). Between days 3 and 7, the mean wound surface area decreased from 6.62 (2.85) to 0.83 (1.62) mm 2 in the control group and 5.07 (0.88) to 1.42 (1.67) mm 2 in the test group. The wound width decreased significantly on day 7 in both groups (p<0.001), with no further changes by day 14. Both groups had a significant increase in inflammation and vascularization on day 3 (p<0.001), with a reduction thereafter. No significant differences in macroscopic and microscopic measurements were observed between the groups at any time point (p>0.05). Conclusion: The Oral-norm gel has no positive healing effects in the palatal mucosa of rats.Item Periodontal status and dental behaviour of heart transplant recipients and healthy controls(2019) Sezgin, Yasemin; Sezgin, Atila; 31661343; AAC-5931-2020Objective: The aim of this study was to compare the periodontal status and dental behaviour of heart transplant recipients with systemically healthy controls. Material and Methods: Forty heart transplant recipients and 40 systemically healthy patients were included. A questionnaire was used to record demographic, systemic health and dental behaviour data, and the following clinical parameters were recorded: plaque index, bleeding on probing, probing depth, gingival recession, and clinical attachment level. Results: Mean probing depth (p = .045), mean gingival recession (p = .016), mean clinical attachment level (p = .021) and mean plaque index scores (p = .001) were higher in heart transplant recipients than the systemically healthy group. However, bleeding on probing was similar in both groups (p > .05). Tooth brushing frequency and number of participants who used dental floss/interdental brush was lower in the heart transplant group. Conclusion: Considering the poor oral hygiene and high clinical periodontal parameters of heart transplant recipients, periodontal evaluation should be done regularly before and after transplantation. The patient's daily oral hygiene regimens should be evaluated carefully in this evaluation session and modified based on their gingival health, manual skill and motivational levels. The importance of oral health and its effects on systemic health should also be explained to the transplant recipients in detail.Item Efficacy of oil pulling therapy with coconut oil on four-day supragingival plaque growth: A randomized crossover clinical trial(2019) Sezgin, Yasemin; Ozgul, Betul Memis; Alptekin, Nilgun Ozlem; 0000-0003-4104-6462; 31780023; AAC-5931-2020; G-1816-2014Objectives: The aim of this study was to evaluate the plaque-inhibiting effects of oil pulling using 4- day plaque regrowth study model compared to 0.2% chlorhexidine gluconate (CHX) containing mouthrinse. Design: The study was an observer-masked, randomized, cross-over design clinical trial, involving 29 volunteers to compare 0.2% CHX and oil pulling therapy in a 4- day plaque regrowth model. After the preparatory period, in which the subjects received professional prophylaxis, the subjects commenced rinsing with their allocated rinsed. On day 5 plaque index (PI), gingival index (GI), stain index (SI), bleeding on probing (BOP) were recorded from the subjects. Each participant underwent a 14- day wash out period and then used the other mouthrinse for four days. Results: Oil pulling therapy presented similar inhibitory activity on plaque regrowth compared with CHX (PI = 1.67 +/- 0.24, 1.61 +/- 0.20, respectively) with less staining (SI = 0.21 +/- 0.13, 0.47 +/- 0.27, respectively). In addition, GI and BOP was similar in both groups (p > 0.05). Conclusion: Oil pulling with coconut oil seems to have similar plaque inhibition activity as CHX. In addition it caused less tooth staining than CHX. These findings suggest that oil pulling therapy may be an alternative to CHX rinse.Item Effects of self-ligating and conventional brackets on halitosis and periodontal conditions(2015) Kaygisiz, Emine; Uzuner, Fatma Deniz; Yuksel, Sema; Taner, Levent; Culhaoglu, Rana; Sezgin, Yasemin; Ates, Can; 25101909Objective: To evaluate the effects of fixed orthodontic treatment with steel-ligated conventional brackets and self-ligating brackets on halitosis and periodontal health. Materials and Methods: Sixty patients, at the permanent dentition stage aged 12 to 18 years, who had Angle Class I malocclusion with mild-to-moderate crowding were randomly selected. Inclusion criteria were nonsmokers, without systematic disease, and no use of antibiotics and oral mouth rinses during the 2-month period before the study. The patients were subdivided into three groups randomly: the group treated with conventional brackets (group 1, n = 20) ligated with steel ligature wires, the group treated with self-ligating brackets (group 2, n = 201, and the control group (group 3, n = 20). The periodontal records were obtained 1 week before bonding (T1), immediately before bonding (T2), 1 week after bonding (T3), 4 weeks after bonding (T4), and 8 weeks after bonding (T5). Measurements of the control group were repeated within the same periods. The volatile sulfur components determining halitosis were measured with the Halimeter at T2, T3, T4, and T5. A two-way repeated measures of analysis of variance (ANOVA) was used to compare the groups statistically. Results: No statistically significant group x time interactions were found for plaque index, gingival index, pocket depth, bleeding on probing, and halitosis, which means three independent groups change like each other by time. The risk of tongue coating index (TCI) being 2 was 10.2 times higher at T1 than at T5 (P < .001). Therefore, the probability of higher TCI was decreased by time in all groups. Conclusions: The self-ligating brackets do not have an advantage over conventional brackets with respect to periodontal status and halitosis.Item Effects of platelet-rich fibrin on healing of intra-bony defects treated with anorganic bovine bone mineral(2017) Sezgin, Yasemin; Uraz, Ahu; Taner, I.Levent; Culhaoglu, Rana; 28146219; AAC-5931-2020Anorganic bovine bone mineral (ABBM) is extensively used in the treatment of intra-bony defects. Platelet-rich fibrin (PRF) is a new-generation platelet concentrate with a simplified technique. Although certain studies have reported the use of PRF in the treatment of intra-bony defects, to date, none of them have evaluated its additive effects with ABBM. Therefore, a randomised, split-mouth clinical trial was conducted to compare healing of intra-bony defects treated with an ABBM-PRF combination with healing of those treated with ABBM alone. By using a split-mouth design, 15 paired intra-bony defects were randomly treated with either ABBM alone (control group) or ABBM-PRF combination (test group). Following clinical parameters and radiographical measurements were recorded at baseline and 6 months after treatment: plaque index (PI), gingival index (GI), probing depth (PD), gingival recession (GR), clinical attachment level (CAL), vertical bone loss, depth of defect and defect angle. Preoperative clinical and radiographical measurements were similar for the test and control groups. Statistically significant reductions in GI, PD, CAL, vertical bone loss, depth of intra-bony defect and widening of defect angle were detected after treatment in both groups. With respect to inter-group analysis, gain in CAL was significantly greater in the test group than in the control group, whereas no inter-group differences were observed in any other parameter. The results of this study indicate that both therapies are effective in the treatment of intra-bony defects.