Fakülteler / Faculties

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    Smoking and Lower Urinary Tract Symptoms
    (2015) Bolat, Mustafa Suat; Akdeniz, Ekrem; Ozkaya, Sevket; Batur, Ali Furkan; Kutman, Kerem Gencer; Goren, Resit; Erdemir, Fikret; Ece, Ferah; 0000-0002-2001-1386; 26706744; Y-6143-2019
    Purpose: Pharmacologic effects of nicotine are multifaceted and complicated. Despite numerous studies, the effect of smoking on lower urinary tract functions, have not been yet studied in detail. In this study, we aimed to investigate the effects of smoking addiction on lower urinary tract and sexual functions on the basis of respiratory functions. Materials and Methods: A total of 186 male patients who have been evaluated between May 2014 and January 2015 were recruited in this study. Smoking history, respiratory symptoms, respiratory function tests, uroflowmetry parameters relating to lower urinary tract symptoms (LUTS), prostate volume, post-voiding residual urine volume and sexual functions of patients have been retrospectively investigated. Results: We determined that as the mean number of cigarettes smoked daily increases, post-void residual urine volume and International Prostate Symptom Score (IPSS) also increase. Moreover in accordance with this finding, mean urinary flow rates and quality of life scores were statistically significantly decreased. In smoking addicts who have high mean package/year, post-void residual urine volume and IPSS levels were increased but proportionately maximum urinary flow rate and average urinary flow rate plus quality of life scores were found to be statistically significantly decreased. In patients with forced expiratory volume in first second:forced vital capacity (FEV1/FVC) ratio less than 80%, mean urinary flow rates were found to be statistically significantly low. Also, we determined that in smoking addicts who have high mean package/year, erectile functions were statistically significantly impaired. Conclusion: We showed negative impacts of smoking addiction on LUTS, patient's quality of life, and sexual functions.
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    The Effect of Low-Level Laser Therapy As an Adjunct to Non-Surgical Periodontal Treatment on Gingival Crevicular Fluid Levels of Transforming Growth Factor-Beta 1, Tissue Plasminogen Activator And Plasminogen Activator Inhibitor 1 in Smoking and Non-Smoking Chronic Periodontitis Patients: A Split-Mouth, Randomized Control Study
    (2017) Pamuk, F.; Lutfioglu, M.; Aydogdu, A.; Koyuncuoglu, C. Z.; Cifcibasi, E.; Badur, O. S.; 28394081; AAI-1077-2019
    Background and ObjectiveThis study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to scaling and root planing (SRP) on smoking and non-smoking patients with chronic periodontitis. Material and MethodsThe study was conducted using a split-mouth design with 30 patients with chronic periodontitis (15 smokers, 15 non-smokers) and 30 healthy individuals matched for age, sex and smoking status as controls. Groups were constituted as follows: Cp+SRP+Sham: non-smokers with chronic periodontitis treated with SRP; Cp+SRP+LLLT: non-smokers with chronic periodontitis treated with SRP+LLLT; SCp+SRP+Sham: smokers with chronic periodontitis treated with SRP; SCp+SRP+LLLT: smokers with chronic periodontitis treated with SRP+LLLT; C: control group comprised of periodontally healthy non-smokers; SC: control group comprised of periodontally healthy smokers. LLLT was first applied on the same day as SRP and again on days 2 and 7 after SRP treatment. Clinical parameters were recorded before non-surgical periodontal treatment (baseline) and on day 30. Gingival crevicular fluid samples were collected before periodontal treatment (baseline) and during follow-up visits on days 7, 14 and 30. Gingival crevicular fluid transforming growth factor (TGF)-1, tissue plasminogen activator (tPA) and plasminogen activator inhibitor 1 (PAI-1) levels were measured using enzyme-linked immunosorbent assay. ResultsAll clinical parameters showed significant reductions between baseline and day 30 following SRP treatment in both the LLLT and sham groups (P<.001). No significant differences were observed between the LLLT and sham groups of either the smokers or non-smokers (P>.05). Gingival crevicular fluid PAI-1 levels decreased significantly in the SCp+SRP+sham and SCp+SRP+LLLT groups (P<.05), and gingival crevicular fluid tPA levels decreased significantly in the Cp+SRP+sham, Cp+SRP+LLLT and SCp+SRP+LLLT groups (P<.05). Gingival crevicular fluid TGF-1 levels decreased significantly in all treatment groups (P<.05). Although no significant differences were found between the gingival crevicular fluid PAI-1, tPA and TGF-1 levels of the LLLT versus sham groups (P>.05) at any of the time points measured, both LLLT groups showed significant reductions in tPA/PAI-1 ratios over time. ConclusionWithin the limits of this study, LLLT may be understood to play a role in the modulation of periodontal tissue tPA and PAI-1 gingival crevicular fluid levels, particularly in smoking patients with chronic periodontitis, and may thus be recommended as an adjunct to non-surgical periodontal treatment.
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    Smoking Prevalence among Healthcare Workers and the Effects of the COVID-19 Pandemic Process on the Frequency of Smoking in Turkey
    (2021) Yildirim, Berna Botan; Torun, Serife; Akcay, M. Sule; 0000-0002-6530-6153; ABF-1652-2021
    This cross-sectional study aims to evaluate the prevalence of smoking among healthcare workers and to investigate the anxiety level of healthcare professionals who have knowledge of COVID-19-related mortality and morbidity and are burdened by the anxiety and stress caused by the pandemic, and its effect on their smoking habits. An online questionnaire was used to facilitate the participation of busy healthcare workers. The survey was shared on all health platforms and various social network groups (Facebook, WhatsApp, etc.) for doctors (specialists, physicians, residents, dentists), nurses, and all other healthcare workers This questionnaire consisted of two tests, namely the Beck Anxiety Scale (BAS) and the Fagerstrom Nicotine Dependence Test (FNDT), and sociodemographic questions. A total of 806 healthcare workers, of whom 74.2% were physicians, 8.8% were midwives/nurses, and 15.1% were assistant health workers, participated in the study. Among all the participants, 501 (62.1%) were nonsmokers, 305 (37.9%) were smokers, and 8(1%) resumed smoking during the pandemic. In terms of the smoking habits of the participants during the pandemic period, 34% of the women who smoked had increased their amount of smoking. With respect to the smoking cessation rates of the participants, the physicians had quit or reduced smoking more than the other participants. The rate of smoking cessation in our study was 2.23%. Among those who quit, 88.8% were doctors, and the rate of quitting among them was 7.8%.