Fakülteler / Faculties

Permanent URI for this communityhttps://hdl.handle.net/11727/1395

Browse

Filters

2018 - 201912020 - 20231

Settings

search.filters.applied.f.rights: search.filters.rights.info:eu-repo/semantics/closedAccessSubject: search.filters.subject.device

Search Results

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Design and Construction of Affordable and Domestic Device for Carbon Nanoparticle Synthesis
    (2018) Aykutlu, Dilara; Okursoy, Berkay; Kocum, Ismail Cengiz; Cokeliler Serdaroglu, Dilek
    Nanoparticles are structures below 100 nanometer and used for molecular imaging with gene therapy, implementation of many biomedical applications such as biosensor, cancer-pathology diagnosis and treatment, targeted drug-making and therefore superior in application areas. The aim of the study is to develop a device that synthesizes carbon nanoparticles by dense medium plasma method; together with hardware, software and mechanical design. Dense medium plasma is an easy synthesis approach with low cost; However, it is necessary for the user of this device to be more comfortable to use, feasible, portable and suitable for market. Moreover there is no commercial device for synthesing carbon nanoparticles by dense medium plasma technique. This research presents details of construction of affordable device for carbon nanoparticle sythesis. Prototype is an unique domestic product and contains integrated hardware, software and mechanical probe parts. Hardware part consists of control, power unit and induction coil unit and these three units are connected to each other. The power unit ensures that the mosfets are triggered by a certain voltage from the control unit. The induction coil unit is induced by turning the low voltage to high voltage. In the mechanical part, probe design supplies discharge betweeen electodes which are fed by argon gase that converts benzene to the carbon nanoparticles. The probe reaches the resonance frequency and to make it easier to adjust the distance between the bottom and top electrode, a spindle system is used. Software operation is measuring high voltage. To make the appliance portable, moreover wheeled table production was done. As a result, signal and power card tests were made, it was observed that the high voltage circuit, the signal circuit and the induction coil cause radiation. More nanoparticle production was achieved with the controllable distance between the bottom electrode and the top electrode of probe. The efficiency of the synthesis was improved and the usage of the device was made practical. Finally prototype device that is usable for synthesis nanoparticles by dense medium technology is constructed affordablity and presented with all details.
  • No Thumbnail Available
    Item
    Effects of Combined Visible and Infrared Light Rhinophototherapy in Patients With Allergic Rhinitis
    (2023) Koycu, Alper; Bas, Ceren; Musabak, Ugur H.; Erbek, Selim Sermed; Koca, Huseyin Samet; Babakurban, Seda Turkoglu; Bahcecitapar, Melike; https://orcid.org/0000-0003-1290-3509; 36266929; AAF-3650-2021
    Background Intranasal phototherapy offers an alternative treatment method for patients with allergic rhinitis who cannot benefit from intranasal corticosteroids and oral antihistamines. Different wavelengths have been tried with promising results. Objective In this present study, we aimed to investigate the effects of visible light-infrared light phototherapy on clinical improvements together with its cytologic effects in patients with allergic rhinitis. Methods Patients with confirmed allergic rhinitis were given a 4-week course of intranasal phototherapy treatment. Weekly symptom questionnaires were applied to monitor clinical effects. Nasal lavage specimens were obtained before the start and at the completion of the 4-week therapy. Fluorescence-activated cell sorting analyses of CD16(+), CD24(+), and CD 45(+) cells were performed. Statistical analyses are performed of weekly changes in symptoms and cell counts. Results CD45(+)CD16(high)CD24(+) neutrophil count in nasal lavages decreased significantly whereas CD45(+)CD16(dim/-)CD24(+) eosinophil counts significantly increased and CD45(+) granulocyte counts remained unchanged. Symptom scores including nasal itching, nasal discharge, nasal obstruction, sneezing, eye itching, throat itching, and ear itching all statistically decreased compared to baseline at the end of 4 weeks. Conclusion Four-week course of intranasal phototherapy with visible and infrared light leads to clinical improvement in allergic rhinitis patients.