Fakülteler / Faculties
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Item Effects of Creative Arts Intervention on Anxiety, Depression and Sleep Quality Among Bone Marrow Transplantation Patients During Protective Isolation(2023) Sertbas, Gulcin; Ok, Elif; Unver, Vesile; https://orcid.org/0000-0003-4342-4965; 35583995; HGT-8047-2022BackgroundProtective isolation remains part of the standard of care for patients undergoing hematopoietic stem cell transplant in many places of the world. The consequences of protective isolation include increased anxiety and depressive symptoms.ObjectiveThe aim of this study was to determine the effects of creative interventions performed during the protective isolation period on anxiety, depression symptoms, and sleep quality of patients who underwent bone marrow transplantation (BMT).Interventions/MethodsThis study was a randomized, controlled, pre-post pilot design. A total of 20 patients made up the sample group. Participants were randomly assigned to the experimental (n = 9) or control group (n = 11). Hospital Anxiety and Depression Scale was applied to patients on the first day of admission to the unit and on the day of discharge. Questions prepared by researchers on sleep quantity and quality were administered every day during the patients' hospitalization. The patients in the experimental group carried out creative arts intervention for a total of 60 minutes a day, 3 to 4 days a week, while they were in the unit.ResultsThere was no difference in depression, anxiety, and sleep quality scores between the groups after intervention. However, depression and anxiety scores significantly decreased after the intervention in the experimental group, and sleep quality scores improved significantly.ConclusionCreative arts intervention may be beneficial for anxiety, depression, and sleep problems among patients undergoing BMT.Implications for PracticeCreative arts intervention is effective in coping with anxiety, depression, and sleep problems that patients may experience due to social isolation during the BMT process.Item The Effect of Infliximab on Depressive Symptoms in Patients with Ankylosing Spondylitis(2015) Ersozlu Bozkirli, E. D.; Keskek, S. O.; Bozkirli, E.; Yucel, A. E.; 0000-0002-1644-6790; 25702318; I-6542-2012; E-9887-2014; 0000-0002-4860-9072Objectives: Ankylosing spondylitis is a chronic inflammatory disease which physically, psychologically, and socially affects the patient's life. Previous studies have reported a correlation between ankylosing spondylitis and depression. In this study we investigated the effect of infliximab on depression in ankylosing spondylitis patients. Methods: A total of 29 patients with ankylosing spondylitis were enrolled in this prospective study Infliximab was administered intravenously at a dose of 5 mg//kg at baseline, weeks 2 and 6. The measurements of morning stiffness, modified Schober's test, chest expansion, erythrocyte sedimentation rate, C-reactive protein, Bath ankylosing spondylitis disease activity index, Bath ankylosing spondylitis functional index and Beck depression inventory scores were compared between baseline and 12th week. Results: The modified Schobers' quotes test and chest expansion increased, the morning stiffness duration, erythrocyte sedimentation rate and C-reactive protein levels decreased after infliximab treatment (p<0.001, respectively). There was statistically significant decrease in Bath ankylosing spondylitis disease activity index, Bath ankylosing spondylitis functional index and Beck depression invantory scores of patients after 12 weeks (p<0.001, respectively). Conclusion: Infliximab can improve depression and its symptoms in patients with ankylosing spondylitis.Item Self-Efficacy, Depression and Self-Care Activities of People with Type 2 Diabetes in Turkey(2017) Kav, Sultan; Yilmaz, Arzu Akman; Bulut, Yasemin; Dogan, Nevin; 29218959Background: Self-efficacy related to self-care behaviors in people with type 2 diabetes has been well reported. However no work has been reported in Turkey that uses reliable instruments to examine the relationships among self-care activities, depression and self-efficacy. Aim: This study aims to investigate self-care activities, depression and self-efficacy among people with type 2 diabetes in Turkey. Methods: The sample included 200 patients with type 2 diabetes from an endocrinology out-patient clinic at a university hospital. Self-care activities, self-efficacy, and symptoms of depression were measured using established instruments: The Summary for Diabetes Self Care Activities, the Self-Efficacy Scale, and the Beck Depression Inventory. Descriptive and correlational statistics were used in data analysis. Findings: One in three (37.5%) of participants had depression symptoms. Beck Depression Inventory scores were higher in women and in those with a lower education level, had diabetic complications and difficulty in meeting health care costs. The mean self-efficacy score was 66.5 14.0; those who lived alone, were unemployed and knew their HbA1c level had significantly higher scores (p <.05). Demographic and diabetes characteristics including age, education, social support, diabetes complications, HbA1c level, and having diabetes education were found to be significantly associated with all self-care activities except smoking.Conclusion: The association between self-efficacy and self-care activities was positive. Interventions to improve patients' self-efficacy and self-care are needed in order to maximize diabetes self-management.(C) 2015 Australian College of Nursing Ltd. Published by Elsevier Ltd.Item Factors Affecting Risk of Anxiety and Depression Among Diabetic and Hypertensive Patients Who Refer to Family Health Centers(2018) Emre, Nilufer; Topal, Kenan; Edirne, Tamer; Gereklioglu, CigdemThis cross-sectional study was carried out to investigate the factors which influence risk of anxiety and depression among diabetic and hypertensive patients who refer to family health centers. The Hospital Anxiety and Depression Scale (HADS) was applied for assessment of emotional status of the patients and the Hypertension Compliance Assessment Scale (HCAS) was applied for assessment of adherence to anti-hypertensive therapy. Of a total of 380 patients, 170 had hypertension (HT), 83 had type 2 diabetes mellitus (T2DM), and 127 had both HT and T2DM. According to HADS, 18.7% of the patients had risk of anxiety, 24.7% had risk of depression, and 12.6% had both risk of anxiety and depression. Mean HAD-Anxiety (HADS-A) score and HADS-Depression (HADS-D) score were significantly lower in the patients who had an adequate compliance to medication therapy (5.1 +/- 4.1 and 3.8 +/- 3.4, respectively) compared to the patients who had a low compliance to therapy (7.6 +/- 4.3 and 5.8 +/- 4.0, respectively) according to the Hypertension Compliance Assessment Scale ((2)=15.26, p<0.01 and (2)=13.80, p<0.01). Mean HADS-D score was found significantly lower among the diabetic patients with good glycemic control (3.7 +/- 2.9) compared to the patients with poor glycemic control (4.5 +/- 3.7) ((2)=25.00, p<0.05). Anxiety and depression are among the most frequent disorders as hypertension and diabetes in primary care setting. We revealed that risk of anxiety and/or depression was greater among hypertensive and diabetic patients, consistently with the previous studies. Our study also revealed that this condition negatively affected treatment compliance in hypertensive patients and glycemic control in diabetic patients.Item Anxiety, Depression, and Anger in Functional Gastrointestinal Disorders: A Cross-Sectional Observational Study(2018) Cakmak, Berna Bulut; Ozkula, Guler; Isikli, Sedat; Goncuoglu, Ibrahim Ozkan; Ocal, Serkan; Altinoz, Ali Ercan; Takintuna, Nilgun; 0000-0003-3719-9482; 0000-0003-2233-2105; 30103181; E-7929-2013; ABH-4817-2020; J-4811-2014Previous studies have identified a link between anger and somatization. However, little is known about the associations between anger and the development and progression of Functional Gastrointestinal Disorders (FGID). The study aim was to determine the associations between FGID and anger, anxiety, and depression. Participants in this cross-sectional observational study were 109 consecutive patients aged 18-64 years with FGID at Gastroenterology Clinic of Baskent University Hospital. A control group comprised of 96 individuals with no chronic gastrointestinal disorders recruited via snowball sampling. Sociodemographic and clinical information were obtained and participants completed the Hospital Anxiety and Depression Scale and the State-Trait Anger Expression Inventory-2. FGID participants scored higher than controls on depression, anxiety, state anger, and anger expression-in. When the FGID group was divided into upper and lower gastrointestinal symptom groups, the lower symptom group showed higher anger expression-out scores than the upper symptom group. Anger may contribute to the etiology and development of FGID. This is the first study to demonstrate a significant psychological difference between individuals with lower and upper FGID. Interdisciplinary collaboration with gastroenterologists and psychiatrists could strengthen FGID evaluation and may improve treatment compliance.Item Association between polarity of first episode and solar insolation in bipolar I disorder(2022) Bicakci, Sule; 0000-0003-4787-9860; 35932492; AAJ-8555-2021Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar inso-lation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P <= 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.Item The relationship between pain and clinical parameters, depression, anxiety and sleep quality in patients with spinal injury(2022) Balikci, Sibel; Bardak, Ayse NurObjective: To examine the frequency of pain in individuals with spinal cord injury, and to assess the relationship of pain with functional status, sleep quality, anxiety and depression levels. Method: The prospective, cross-sectional study was conducted from March to June 2018 at Istanbul Physical Medicine and Rehabilitation Training and Research Hospital, Istanbul, Turkey, and comprised adult patients of wither gender with spinal cord injury who were in the rehabilitation phase both on outpatient and inpatient basis. Data was collected using a questionnaire exploring demographic and clinical features. The presence of pain was assessed using the Leeds Assessment of Neuropathic Symptoms and Signs scale and, in case pain was found present, it was categorised as neuropathic, nociceptive and mixed type pain types. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index, while the Hospital Anxiety and Depression scale was used to evaluate anxiety and depression levels. Data was analysed using SPSS 20.Results: Of the 150 patients, 104(69.3%) were males and 46(30.7%) were females. The median age of the sample was 46 (IQR:20.52) years. Neuropathic pain was observed in 61(40.7%) patients, nociceptive in 32(21.3%) and mixed type in 12(8%). Depression was found in 71(47.3%) patients, poor sleep quality in 41(27.3%) and anxiety in 35(23.3%). Sleep, anxiety and depression scores were higher in the presence of neuropathic and nociceptive pain (p<0.05). Conclusion: Pain is a common complication in patients with spinal cord injury. In the presence of pain, sleep quality is worse, and anxiety and depression levels are high.Item Emotional and physical maltreatment, early maladaptive schemas, and internalizing disorders in adolescents: a multi-group path model of clinical and non-clinical samples(2021) Yigit, Ibrahim; Kilic, Harun; Guzey Yigit, Melike; Celik, Cihat; 0000-0003-0556-9960; W-5957-2018Many studies have supported the mediating role of maladaptive schemas in the relationship between early childhood adversity and psychopathology in both clinical and non-clinical adolescent samples. However, to the best of our knowledge, there has been no study to simultaneously test the mediating role of maladaptive schemas in a combined model included in both clinical and non-clinical samples of adolescents. The sample of the study consisted of 132 non-clinical (M = 15.65, SD = 1.15) and 193 clinically referred (M = 15.05, SD = 1.07) adolescents. Criteria for the clinical sample included being diagnosed with generalized anxiety disorder, depressive disorder or mixed anxiety and depressive disorder. Participants were administered The Childhood Trauma Questionnaire, Young Schema Questionnaire, Children's Depression Inventory, and Spielberger State-Trait Anxiety Inventory. The aim of the present study was to test the hypothesized mediation model that Disconnection/Rejection and Impaired Autonomy schema domains would mediate the relationship between childhood maltreatment and psychological symptoms for clinical and non-clinical adolescent samples, separately. Furthermore, we tested whether structural paths of the model were different across the two samples, using multiple-group path analysis. Results showed that Disconnection/Rejection and Impaired Autonomy emerged as significant mediators in both samples. In addition, only the association between Disconnection/Rejection and depression was stronger in the clinical sample compared to the non-clinical sample.Item Comparison between the use of vitamin d supplement by 20-49 year old women and their nutrition and depression status(2021) Soykurt, Seniha Cukurovali; Tayfur, Muhittin; Celen, Emine UlucamObjective: Aim of this study is to determine the possible relation between the nutritional status, food choices, eating habits, and Vitamin D supplement use of pregnant women between 20-49 years of age, and depression. Methods: The study was conducted between December 2018 and January 2019, on a total of 150 pregnant women between the ages of 20 and 49, who were admitted to Ankara Ataturk Training and Research Hospital Obstetrics and Gynaecology Policlinic. A questionnaire was used in order to identify personal data of the individuals, levels of serum Vitamin D, depression status, physical changes and other information regarding the changes in food consumption. Dietary habits and food consumption records of the individuals were obtained through face-to-face interviews. Results: A total of 75 individuals participating in the study used Vitamin D, while the other 75 did not. Of the individuals participating in the study, beck depression score median of those who used Vitamin D was found as 9.00 (IQR =6), while it was 33.00 (IQR =13) for those who did not. When the scores were analyzed based on Vitamin D use, it was found that there were statistically significant differences. Conclusions: There is evidence from epidemiological studies that show that vitamin D deficiency or insufficiency is associated with depression. Therefore, it is appropriate to recommend taking vitamin D supplements to prevent or treat depression in risk groups. Larger studies are needed to examine this situation in detail.Item Psychological domain of quality of life, depression and anxiety levels inin vitrofertilization/intracytoplasmic sperm injection cycles of women with endometriosis: a prospective stud(2020) Ceran, M. U.; Yilmaz, N.; Ugurlu, E. N.; Erkal, N.; Ozgu-Erdinc, A. S.; Tasci, Y.; Gulerman, H. C.; Engin-Ustun, Y.; 0000-0003-1923-2373; 32635772Objective To evaluate the psychological domain of quality of life (PDQoL), anxiety and depression levels of infertile women with endometriosis versus non endometriosis who applied for Assisted Reproductive Technologies (ART). Method This prospective case-control study compromised a total of 105 women who applied for IVF/ICSI program. Ninety-three women were divided into two groups as endometriosis (n = 37) and non-endometriosis (n = 56) after 12 patients who refused to participate in the study were excluded. The WHOQOL-BREF questionnaire, Beck Depression and Anxiety Inventory scales were used to determine the psychological stress levels. Results A significant difference was found between the endometriosis and non-endometriosis groups regarding depression scores, while no significant difference was reported with respect to PDQoL and anxiety (p < 0.01,p = 0.897 andp = 0.058, respectively). A weak but significant correlation was observed between depression and endometriosis (CC: 0.435,p < 0.01). Though anxiety scores were found to be higher in endometriosis group this can not reach statistical significance (p = 0.058). Impact of PDQoL, depression and anxiety scores on pregnancy outcomes were found to be insignificant. Conclusion Women with endometriosis seem to be more susceptible to depression and anxiety than women without endometriosis. Although infertility treatment outcomes are not found to be significantly affected, the impact of depression and anxiety over ART treatment success merit further research.