Fakülteler / Faculties
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Item An In Vivo Comparison of Commonly Used Topical Antimicrobials on Skin Graft Healing After Full-Thickness Burn Injury(2015) Abbas, Ozan L.; Borman, Huseyin; Bahar, Taner; Ertas, Nilgun M.; Haberal, Mehmet; 0000-0002-3462-7632; 24823344; AAJ-8097-2021Topical antimicrobials are frequently used for local control of infections in burn patients. It has been postulated that these agents retard wound healing. There are limited data about the effects of topical antimicrobial agents on skin graft healing. In this study, we aimed to evaluate the effects of nitrofurazone, 1% silver sulfadiazine, and povidone-iodine on skin graft healing. Forty male rats were used in this study. A meshed skin graft, placed on an excised burn wound, was used as a model to compare topical agents with a control group. Skin graft survival rates, closure of meshed graft interstices (based on physical parameters, namely epithelialization and wound contraction), and histological changes were analyzed. Graft take was more than 85% in all groups. There was no difference between the mean values of the percent graft survival for each group (P > .05). Epithelialization occurred significantly earlier in animals in the nitrofurazone group (P < .05). There was no significant difference between groups in wound contraction rates (P >.05). There was no histological difference between the biopsy specimens of skin grafts. In specimens obtained from the interstices of the meshed graft, no significant differences were found among the groups regarding the wound healing parameters (P > .05). We found that nitrofurazone, silver sulfadiazine, and povidone-iodine had no negative effect on graft healing and take in noncontaminated burn wounds.Item Effect of Different Surface-Cleaning Techniques on The Bond Strength of Composite Resin Restorations(2014) Erkut, Selim; Yilmaz, Burak; Bagis, Bora; Kucukemen, Cigdem; Ozdemir, Erdem; Acar, Ozlem; 24939254Statement of problem. Different techniques have been suggested for cleaning dentin surfaces after the removal of an interim prosthesis and before the application of a bonding agent. How different surface-cleaning techniques affect the bond strength of the composite resin restorations is not clear. Purpose. The purpose of this study was to investigate the effects of different surface-cleaning techniques on the bond strength of composite resin restorations and the surface topography of the prepared tooth surfaces. Material and methods. The occlusal surfaces of 25 molars were ground until the dentin was exposed. A bonding agent and interim cement were applied on the teeth. The teeth were divided into 5 groups (n=5) according to the method used for surface-cleaning (microairborne-particle abrasion, alcohol, rubber-rotary instrument, desiccating agent, and control). Once the surfaces of the teeth had been cleaned, the same bonding material was applied to the teeth. A 5-mm-thick composite resin layer was built up. Each specimen was sectioned to microbars, and 6 centrally located beams were selected for microtensile testing (n=30) (1.10 +/- 0.10 mm). The data were statistically analyzed with 1-way ANOVA (1-sample Kolmogorov-Smirnov test). The Bonferroni test was used for significantly different groups (alpha=.05). One specimen from each group was observed under a scanning electron microscope and an atomic force microscope. Energy dispersive x-ray analysis also was performed. Results. Bond strength values were in the following descending order: microairborne-particle abrasion, desiccating agent, alcohol, rubber-rotary instrument, control. Differences between the microairborne-particle abrasion group and the remainder of the groups, desiccating agent-rubber-rotary instrument, desiccating agent-control, alcohol-rubber-rotary instrument, and alcohol-control groups, were statistically significant (P<.05). The microairborne-particle abrasion group displayed the roughest surface and a different surface topography from the remainder of the groups. Increased aluminum was observed in the microairborne-particle abrasion group. Conclusions. Surface-cleaning techniques, except for the rubber-rotary instrument, increased the bond strength of composite resin. The roughest dentin surfaces and highest bond strength were achieved with the microairborne-particle abrasion technique.Item Effectiveness of two desensitizing products: A 6-month randomized clinical, split-mouth study(2020) Kerimova, Leyla; Kiremitci, Arlin; 33439563Purpose: This randomized controlled clinical trial compared the efficacy of a desensitizer containing calcium phosphate with a two-step self-etch adhesive and placebo over a 6-month period. Methods: 50 subjects aged between 2164 years with a sensitivity score of 6 or higher according to the Visual Analog Scale (VAS) in at least three teeth participated in this study. Teethmate Desensitizer, Clearfil SE Bond 2, and placebo (distilled water) were applied randomly to three teeth of each patient. Recall reviews were performed at baseline, 1 week, 1 month, 3 months, and 6 months after treatment, and the sensitivity scores were assessed by air-blast application. The normality of data was analyzed with Shapiro-Wilk. Since the placebo treatment was successful only in a small number of teeth, the three materials could only be compared 10 minutes after the treatment. Data were analyzed with Wilcoxon Test, Friedman and Dunn post-hoc tests (P= 0.05). Results: Sensitivity decreased significantly after application for each of the three test groups when compared to the pretreatment condition (P< 0.05). There were no significant differences between the Teethmate Desensitizer and Clearfil SE Bond 2, and both materials were more effective than the placebo (P< 0.05).