Fakülteler / Faculties
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Item The Effect of Scapular Stabilisation Exercises on Posture and Pain in Patients with Fibromyalgia: A Randomised Controlled Trial(2023) Polat, Hakan; Bayramlar, Kezban; Turhan, Begamhan; 0000-0003-0842-2059; B-8254-2018Background/Aims Fibromyalgia is a complex syndrome characterised by chronic widespread pain, postural problems, sleep disorders, fatigue and psychiatric disorders. This study investigated the effect of scapular stabilisation exercises on cervical posture and pain in patients with fibromyalgia.Methods The study included 59 patients between the ages of 18-60 years. Individuals were divided into two groups: the study group (n=29) and control group (n=30). Both groups underwent hot pack application, transcutaneous electrical nerve stimulation and ultrasonography before the exercises. This application continued for a total of 6 weeks in both groups, 5 days a week. After this treatment, the control group was asked to perform conventional shoulder exercises and the scapular stabilisation group was asked to perform scapular stabilisation exercises. The patients were evaluated in terms of pain and cervical posture.Results Pain levels significantly decreased in both groups after the treatment (P=0.019). A decrease in tragus-to-wall distance occurred in the conventional exercise group (P=0.005). Scapular stabilisation exercises were found to be more effective than conventional exercises In terms of pain (P<0.001) and cervical posture, (P=0.024).Conclusions Both exercise programmes reduced pain levels in patients with fibromyalgia. However, scapular stabilisation exercises were more effective at both reducing pain and improving posture. Physiotherapists can use scapular stabilisation exercises to patients with fibromyalgia to reduce pain, improve posture and reduce the load on the joints.Item Evaluation of Colposcopy After the Addition of Human Papillomavirus Testing to the Turkish Cervical Cancer Screening Program(2023) Gunes, Ali Can; Ozgul, Nejat; Turkyilmaz, Murat; Kara, Fatih; Unlu, Fahriye; Ayhan, Ali; Gultekin, Murat; 37994572Objective: To evaluate colposcopy performance following the human papillomavirus (HPV) DNA screening program in Turkey. Methods: Women aged 30-65 years are screened for cervical cancer every 5 years, with individuals positive for HPV 16 and/or 18 or other high-risk HPV types with abnormal cytology referred for colposcopy. Both HPV test and cytology are obtained at the same visit. If HPV is negative, cytology will not be assessed. However, if HPV is positive, both cytology and HPV genotyping will be performed. Colposcopy-require was defined as HPV 16/18 positivity or abnormal smear results with any hrHPV positivity, and the remaining patients (normal smear with hrHPV positivity other than HPV 16/18) were grouped as colposcopy non-required. National data on colposcopy outcomes and unnecessary performance rates in February 2018-2019 were evaluated via a questionnaire. Results: A total of 9808 patients were included, divided based on colposcopy requirement: 5751 (58.6%) patients required colposcopy and 4057 (41.4%) did not. Unnecessary colposcopy was performed on 90.1% of the non-required group (3657 of 4057 patients). In the colposcopy-required group, 4455 patients (79.9%) underwent punch biopsy; 3194 (57.1%), endocervical curettage (ECC); and 421 (7.5%), "see and treat" in the non-required group, the results were 2790 (76.3%), 1957 (53.2%), and 211 (5.7%), respectively. A total of 746 cervical intraepithelial neoplasia (CIN)-3 isolates were detected, including 702 using existing screening and triage with 94.1% sensitivity (702/746). Multiple biopsies were taken in 69.8% (n = 3110) of patients from the colposcopy-required group and 63.7% (n = 1777) from the non-required group. The ECC samples included 19 cervical cancers and 212 >= CIN-3 lesions in the colposcopy-required group, and four cancers and 41 >= CIN-3 lesions in the non-required group. The proportion of >= CIN-3 lesions detected by ECC only was 4.7% (35 of 746 >= CIN-3 lesions). Conclusion: Our results showed high rates of unnecessary colposcopies, and a high percentage of multiple and random punch biopsies and ECC.Item The Effect of Suture Materials with Different Absorption Times on Isthmocele: A Retrospective Study(2023) Yetkinel, Selcuk; Aytac, Pinar Caglar; Kalayci, Hakan; Cok, Tayfun; Durdag, Gulsen Dogan; Yaginc, Didem Alkas; Baran, Safak Yilmaz; Alemdaroglu, Songul; Kilicdag, Esra Bulgan; 0000-0002-2165-9168; 0000-0002-5064-5267; 37306162; AAL-1530-2021; AAC-9940-2020; AAI-9594-2021Objectives: With the increasing rate of cesarean operations, the formation of niches and related early and late complications have been observed more frequently. In this study, we examined the effects of using a suture material that can be absorbed faster than conventional sutures on the formation of niches.Material and methods:This study was designed as a retrospective study and completed with a total of 101 patients. During the cesarean operation, the uterus was closed with Rapide Vicryl center dot in 49 patients and Vicryl center dot in 52 patients. The uterine niche was measured with a sonohysterogram 6 months after the operation. The primary outcome of the study was determined as uterine niche formation and the secondary outcome was the post-menstrual spotting (PMS) rate.Results: Duration of surgery, intraoperative/postoperative blood loss, and hospitalization time were similar between the two groups. Niche formation was significantly lower in the Rapide Vicryl group (22.4%) when compared to the Vicryl group (42.3%) (p = 0.046). Also, PMS was observed significantly lower in the Rapide Vicryl group (16.2% and 52.8% in Rapide Vicryl and Vicryl groups, respectively; p = 0.002).Conclusions:The formation of niches and associated PMS rates were less with suture materials that were absorbed faster.Item Return and Volatility Connectedness in Electronic Warehouse Receipt Market of Turkey(2023) Acikgoz, Turker; 0000-0002-5613-1929; IYJ-0960-2023Over the course of the last century, globalization and integration have increased significantly around the world. The rise in economic and financial globalization and integration has increased the connectedness between national economies and financial markets and secured an important place in the systemic risk spillover. It is important to analyze the issue in terms of different markets. Food prices around the world have increased significantly over the last 20 years. The price and volatility increase associated with food products lead to important socioeconomic and social problems. In this context, it will be important for decision-makers to assess the issue from the perspective of financial markets and to understand and reveal the dynamic structure of food commodity markets. This study aims to examine the connectedness of return and volatility in the Electronic Warehouse Receipt (EWR) market, where agricultural commodities are traded in Turkey, and to analyze its dynamic structure that changes over time. In this study, the Diebold-Yilmaz connectedness measurement method based on the forecast error variance decomposition after the VAR (p) model was used to analyze the connectedness between financial assets. According to the results of the static analysis performed, it was observed that while the return connectedness in the EWR market is very low, the volatility connectedness is at a higher level than the return connectedness. Based on the results of the dynamic analysis, no trend was observed in return connectedness; however, rapid increases and decreases were observed for certain periods. On the other hand, while an increasing trend was observed in the dynamic analysis of volatility connectedness, sudden increases and decreases were observed during periods of crisis. Of all agricultural commodities, it was observed that barley was the asset that sent the most net shock into the system. The EWR market in Turkey has come up recently. The market's structure, dynamics, and synchronization with other markets are still at a low level. The spillover effect of return and volatility shocks in the market are also low. The findings of this study can be used by producers, financial market participants and various decision makers for risk management, hedging and profit maximization purposes.Item Odor and Taste Sensitivity in Children with Attention Deficit/Hyperactivity Disorder(2015) Akin Sari, Burcu; Taskintuna, Nilgun; 0000-0002-9730-7206; HJP-2418-2023; A-7296-2013Objective: Attention Deficit/Hyperactivity Disorder (ADHD) is diagnosed using Diagnostic and Statistical Manual of Mental Disorders criteria, neuropsychological testing, examinations, and parent, teacher, and self-evaluation forms. Diagnosing of ADHD depends on clinical evaluation, others are auxilary methods. No biological, electrophysiological, or neuroimaging markers currently exist to diagnose ADHD. Many studies about the biological markers for diagnosing ADHD have been conducted. Olfactory and gustatory dysfunctions have not been well studied in ADHD for this purpose. For this reason this study aimed to evaluate both the olfactory and gustatory functions of children with ADHD. Methods: A total of 34 children with ADHD and a control group containing 31 children aged 6-15 years participated in the study. We used the Sniffin' Sticks odor tests and propylthiouracil (PROP) bitterness sensitivity test to examine odor and taste sensitivity, respectively. Results: We found no statistically significant differences between the ADHD and control groups in terms of odor sensitivity, odor discrimination, and odor identification. A statistically significant difference between groups was observed in PROP scores. Children in the ADHD group were less sensitive to bitterness than the control group. Conclusion: PROP bitterness test is in an advantageous state for being a marker in advanced years due to ease of use, independence of age and very short test period. As a result, in our study, it is concluded that PROP bitterness test may be a biological marker for ADHD diagnosis, however, further studies are needed.Item Relationship Between Vitamin B12, Homocysteine and Oxidative Stress in Juvenile Idiopathic Arthritis(2016) Bicer, Nihan Cakir; Aksoydan, Emine; Zeybek, Cigdem Aktuglu; Barut, Kenan; Kasapcopur, OzgurJuvenile idiopathic arthritis (JIA), which is one of the rheumatic diseases, is a systemic inflammatory disease characterized by chronic and erosive synovitis that involves peripheral joints. In patients who had been diagnosed with JIA, increasing proinflammatory cytokines, metabolic abnormalities associated with systemic inflammation, may provoke vascular endothelial damage which can cause atherosclerosis. Homocysteine is another metabolite among the factors causing endothelial dysfunction. Homocysteine is an intermediate metabolite which is formed during the conversion of methionine to cysteine and high levels of homocysteine in blood can lead to vascular damage. Dietary folate and vitamin B12 deficiency can cause an increase in blood homocysteine levels. Vitamin B12 is essential for the transfer of methyl group and cell division in humans, but it is also important for the proliferation, maturation and regeneration of the nerve cells. In addition, "functional vitamin B12 deficiency" in which blood vitamin B12 level is in the normal range and without severe clinical symptoms like anemia has also been reported. Studies have showed that vitamin B12 deficiency can lead to oxidative stress without causing significant increase in homocysteine levels by its effects on cytokines, growth factors, nitric oxide metabolism, antioxidant enzymes and producing reactive oxygen species.Item The Effects of Two Different Water Exercise Trainings on Pain, Functional Status and Balance in Patients with Knee Osteoarthritis(2018) Kunduracilar, Zuhal; Sahin, Hulya Guvenir; Sonmezer, Emel; Sozay, Seyhan; 0000-0002-8460-7699; 29475802; AAJ-2936-2021Methods: Eighty-nine female patients who had been diagnosed with knee osteoarthritis were divided into three groups as two experimental and a control group. All groups have received the standard therapy (hotpack, ultrasound, TENS). Both experimental groups underwent water exercise program. While Group 1 performed lower extremity exercise training, Group 2 performed upper extremity exercises as well as trunk exercises in addition to the lower extremity exercises used in the Group 1. The third group was control group who did not receive water exercise treatment. The pain severity was measured with the Visual Analog Scale (VAS). Functional status was assessed by using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Balance was evaluated by using the single leg stance test. Results: The change in VAS scores from pre-to post-treatment was highest in Group 1 (p < 0.001). On the other hand, the change in WOMAC pain, stiffness and physical function values from pre-to post-treatment was highest in Group 2 (p < 0.001). Discussion: Water exercise training was found to be beneficial in the treatment of knee osteoarthritis in both groups. Moreover, adding upper extremity and trunk exercises to the lower extremity exercises was found to be more effective for improving the function. (C) 2018 Elsevier Ltd. All rights reserved.Item Turk Cardiology Association Completion Report: COVID-19 Pandemic and Things to Know About Cardiovascular Diseases (25 March 2020)(2020) Altay, Hakan; Okyay, Kaan; 0000-0001-6134-8826; 32250347; AAK-7355-2020; AAE-1392-2021Item Stereotaxic Biopsy Experience(2020) Dere, Umit Akin; Sahinturk, Fikret; Sonmez, Erkin; Gulsen, Salih; Yilmaz, Cem; Altinors, Mehmet NurAim: To review the outcomes and complications of stereotactic biopsy procedures performed at Neurosurgery Department of Baskent University and make an overall evaluation of the stereotactic biopsy system. Materials and Methods: Medical files of 151 patients who underwent stereotaxic biopsy procedure between 1996 and 2018 were retrospectively analyzed.The , age and gender of the patients, intracranial localization of the lesion and histopathologic diagnosis were evaluated. Result: The series included 84(55.6%) males and 67 (44.4%) females. The average age was 47.7 and the age spectrum was between 26-84 years of age. In 102 cases (67.55%) lesions had lobar localization and in 42 lesions (27.82%) the pathology was deep seated lesion. In 7(4.6 %) there were multiple lesions. A histopathologic diagnosis was obtained in 125 (82.79 %) cases. In 16 (%10.59 %) it was reported as brain tissue and in 10 cases (6.62 %) the histopathologic diagnosis was gliosis. A second stereotactic bipsy procedure was performed in 8 cases while in one patient a third biopsy became necessary. Thirteen patients underwent craniotomy and tumor excision as further therapy. Conclusion: Stereotactic biopsy sampling of intracranial space occupying lesions is a safe, simple and highly diagnostic method. In some cases it may contribute to further therapy. The problems encountered are inconclusive diagnosis, inadequate representation of the specimen due to its limited nature and some technical difficulties.Item The Necessity of Sector Carrying Capacity in Multinational Companies' FDI Location Choice(2019) Baskici, Cigdem; Ercil, Yavuz; AAI-6607-2020The aim of this study is to define the carrying capacity as a new criterion in multinational companies' foreign direct investment (FDI) location choice. The validity of such a definition requires the existence of a causal relationship between FDI and the number of companies at the investment location. As carrying capacity is a function of the sector population, FDI refers to the decisions of foreign investors regarding location choice. With this in mind, the company numbers and FDI data used belonging to 34 sub-sectors of Agriculture, Industry and Services sectors in Turkey between the years of 2006-2016 were analyzed. The Granger causality test was applied to investigate the causal relationship between the company numbers and FDI. As a result of the findings, a causality relationship between the number of companies and FDI was determined in 29 of the 34 sub-sectors. A causality relationship could not be found in 2 sub-sectors. Analysis was not possible in the remaining 3 sub-sectors because of a lack of data. The results show that carrying capacity can be used as decision criterion in multinational companies' FDI location choice. In addition to this main result of the study, predictions for the investment decision are presented in the light of the analyses along with evaluations of the carrying capacity of the Agriculture, Industrial and Services sectors.