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Author: search.filters.author.Ulusoy, Mahmut OguzSubject: search.filters.subject.Anterior segment optical coherence tomography

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    Evaluation of Dry Eye Using Anterior Segment Optical Coherence Tomography in Patients With End-Stage Renal Disease Undergoing Hemodialysis
    (2018) Kal, Oznur; Ulusoy, Mahmut Oguz; Kal, Ali; Tanriaski, Gulsah; Cezairlioglu, Sefik; https://orcid.org/0000-0002-7751-4961; https://orcid.org/0000-0001-7544-5790; 29205873; AAJ-7586-2021; AAJ-4936-2021
    The aim of the present study was to evaluate dry eye parameters with conventional tests and tear meniscus with Anterior Segment Optical Coherence Tomography (AS-OCT) in patients with end-stage renal disease (ESRD). Thirty-eight ESRD patients undergoing hemodialysis, and 40 healthy individuals were enrolled. An ocular surface disease index questionnaire (OSDI) was administered. Before conventional dry eye tests, tear meniscus were evaluated using AS-OCT. After a complete ocular examination, Schirmer and break-up time (BUT) tests were performed and probable corneal staining was investigated. Schirmer test and BUT values were significantly lower in ESRD patients (P<0.05). OSDI scores and corneal staining scores were significantly higher in ESRD patients (P<0.05). Tear meniscus height, tear meniscus depth, and tear meniscus area, which were obtained by AS-OCT were significantly lower in patients with ESRD (P<0.05). Tear meniscus evaluation using AS-OCT is an effective and non-invasive method to assess tear meniscus in patients with ESRD. Patients with ESRD undergoing hemodialysis should obtain regular ophthalmic examination, especially for dry eye.
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    Evaluation of dry eye disease in newly diagnosed anxiety and depression patients using anterior segment optical coherence tomography
    (2019) Ulusoy, Mahmut Oguz; Isik-Ulusoy, Selen; Kivanc, Sertac Argun; 31417939
    Background We aimed to evaluate dry eye diseases (DED) in patients with newly diagnosed depression and anxiety patients. Methods Forty newly diagnosed depression, 35 anxiety patients, and 37 controls without any history of taking psychiatric drugs (or before the beginning of psychiatric medication) and topical ophthalmic drop use, were included in the study. All depression and anxiety diagnoses were performed by an experienced psychiatrist. Beck depression and anxiety tests were used to measure disease severity. Tear film break up time (TBUT), Schirmer's test, Oxford scores and ocular surface disease index (OSDI) were admiinistered to participants. Anterior segment optical coherence tomography was used to measure tear meniscus heights (TMH), tear meniscus depths (TMD) and tear meniscus areas (TMA). Results In anxiety and depression groups, Schirmer's test (mm) (7.24 +/- 6.02, 6.58 +/- 4.9 and 18.79 +/- 4.9 respectively, p < 0.05) and TBUT (s) (5.62 +/- 3.1, 5.6 +/- 3.5 and 13.37 +/- 1.7 respectively, p < 0.05) were significantly lower than control group. In addition, OSDI and Oxford scores were significantly higher than controls. OSDI scores were 28.01 +/- 19, 30.43 +/- 18.49, 14.38 +/- 8.14 respectively (p = 0.002) and Oxford scores were 1.9 +/- 0.7, 2.1 +/- 0.6 and 0.7 +/- 0.4 respectively (p = 0.001). TMD, TMH and TMA values were significantly lower in anxiety and depression groups compared with control groups. Correlations between disease inventory scores and dry eye tests were detected. Conclusions This study showed a relation between DED and newly diagnosed anxiety and depression patients with no history of psychiatric drug use. The presence of correlation between dry eye tests and disease inventory scores strengthens this association. This is an important knowledge that need to be evaluated in these patients before starting psychiatric medication.