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Author: search.filters.author.Taskintuna, NilgunSubject: search.filters.subject.depression

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    Association of Body Mass Index with Depression and Alexithymia
    (2014) Karagol, Arda; Ozcurumez, Gamze; Taskintuna, Nilgun; Nar, Asli; https://orcid.org/0000-0002-3548-5517; https://orcid.org/0000-0003-0998-8388; ABE-8882-2020; AAK-3556-2021; AAA-2743-2021
    Objective: Association between body mass index (BMI) and mental disorders had long been investigated. Recent researches declare a relation between obesity and depressed mood as well as clinical depression. On the other hand mental disorders such as alexithymia are also found to be correlated with an increased risk of obesity. Therefore we aimed to evaluate depression and alexithymia together among normal, overweight and obese adults in order to assess what kind of an association is there between BMI, depression and alexithymia. Methods: We enrolled 100 adults, aged between 18 to 67 from department of endocrinology outpatient clinic whom had normal levels of TSH, fT3 and fT4 thyroid hormones and formed three groups according to their Body Mass Index (BMI). Individuals who had had BMI between 18.5 and 24.99 formed the normal, BMI between 25 and 29.99 formed the overweight and BMI 30 and above formed the obese groups. All three groups were evaluated by Composite International Diagnostic Interview for clinical diagnosis and also given Toronto Alexithymia Scale-26 item (TAS-26) as well as Beck Depression Inventory (BDI). Results: There was a positive relation between BMI and current depressive episode and this finding was stronger in women. There was no such relation with lifelong depression. TAS-26 total and subscale scores revealed no difference between three groups. As BDI total scores got higher TAS-26 scores were higher. Hence there was a strong positive relation between depression and alexithymia. Conclusion: Our findings indicate that higher BMI increases current depressive episode. No association is found between BMI and lifelong depression. Depression and depression severity are strongly associated with alexithymia. Contradictive with literature, alexithymia and its severity are not found to be related with BMI. Following overweight and obese individuals is important to offset the adverse outcomes of depression.
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    Factors Associated with Depression in Obsessive-Compulsive Disorder: A Cross-Sectional Study
    (2015) Altintas, Ebru; Taskintuna, Nilgun; 28360738
    Introduction: Major depressive disorder (MDD) is the most frequent comorbid psychiatric condition associated with obsessive-compulsive disorder (OCD). This study aimed to evaluate the prevalence of current depression in OCD, differences in socio-demographic and clinical characteristics, and obsessive-compulsive symptoms between OCD patients with and without depression. Additionally, factors associated with comorbid depression were investigated in our study. Methods: In total, 140 OCD patients, of which 63 were OCD patients with MDD (OCD+MDD, n=63) and 77 were OCD patients without depression (OCD-MDD, n=77) were included in the study. All patients were diagnosed with OCD using the Structured Clinical Interview for DSM-IV. The Yale-Brown Obsessive-Compulsive Scale, Beck Anxiety Scale, and Beck Depression Scale were administered to all patients. After the socio-demographic and clinical variables and scales were accomplished, the OCD patients divided into two groups as OCD with or without depression and we compared their mean scores of the variables and scales. Univariate analyses were followed by logistic regression. Results: There were no significant differences in age, gender, marital status, period without treatment, profession, medical and family history, and social support between the two groups. Anxiety, depression, and obsession and compulsion scores were significantly higher in the OCD+MDD group. The avoidance, insight, instability, and retardation scores of the OCD+MDD group were also significantly higher than those of the OCD-MDD group. Conclusion: Our study suggests that many factors are strongly associated with depression in OCD. Positive correlations between poor insight, severity of obsession and compulsion, and stressful life events during the last six months increased the risk of depression in OCD. Our study suggests that high level of avoidance, instability and retardation, history of suicidal attempt, and delayed treatment are other notable factors associated with the development of depression in OCD.