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Item Effects of Glycerol Test on Resonance Frequency in Patients with Meniere's Disease(2019) Oz, Isilay; Hizal, Evren; Cam, Osman Halit; Ozluoglu, Levent Naci; 31715604Objective: To evaluate resonance frequency (RF) values via dehydration effects in the inner ear caused by the glycerol test, which is used as a diagnostic method for Meniere's disease (MD). Methods: Twenty adult patients with unilateral MD were included in the study. Before, and then at 1, 2, and 3 h after administration of glycerol (1 g/kg), pure-tone hearing levels (125-8,000 kHz) and multifrequency tympanometry tests were performed. As a control, the RF values of the ears of 25 healthy subjects (i.e., 50 ears) were compared to the affected and unaffected ears in the 20 MD patients. Results: There was a significant difference between the RF values of affected and healthy ears before glycerol administration (p = 0.047). The RF values before and after glycerol administration into affected ears were compared. The average RF values decreased significantly from 748.0 +/- 402.1 to 808.0 +/- 410.1 Hz at 1 h after glycerol intake, and this value increased during the subsequent hours. There were no statistically significant differences between the pure-tone levels before and 1 h after glycerol administration, but a significant decrease was observed at 3 h. Conclusion: We suggest that MD has different inner-ear dynamics and normal RF values when compared to healthy ears. Furthermore, decreased inner ear pressure causes reduction of the mass effect and a stiffening of the annular ligament. We conclude that pre- and post-RF tests should be added to the test battery for diagnosis of MD.Item Effect of Body Mass Index on Middle Ear Resonance Frequency(2018) Sozen, Miray; Oz, Isilay; Erbek, Selim; 29460823OBJECTIVE: Multifrequency tympanometry (MET) analyzes tympanograms obtained using different probe tones between 226 and 2000 Hz. An important parameter of MET is resonance frequency (RF). Studies have recently demonstrated that the RF value can vary depending on many factors. To provide new data regarding MET, middle ear RF values were investigated with regard to body mass index (BMI). MATERIALS and METHODS:This study included 78 volunteers (i.e., 156 ears) aged 18-40 years who did not have healing loss and whose otoscopic examinations were normal. Hearing thresholds were measured using pule tone audiometry, and RF values were recorded with immitansmetric measurements. The participants were divided into the following three groups according to their BMI: <18.5 kg/m2, Group 1; 18.5-24.9 kg/m(2), Group 2; and >25 kg/m(2), Group 3. The RE values were also analyzed. RESULTS: Although there was no significant difference between Groups 1 and 2 in terms of RF values, a significant difference was observed between Groups 1 and 3 and between Groups 2 and 3. CONCLUSION: In the light of these data, BMI values should be considered when middle ear RF values are assessed.