Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4809
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Item The effect of helicobacter pylori eradication on atrophic gastritis and intestinal metaplasia : a retrospective single center research(2020) Suna, N.; Etik, D.; Ocal, S.; Gunduz, C.; Acikgoz, A.; Bildik, I; Gursoy, A.; Kasgoz, I; Tuleylioglu, H.; Boyacioglu, A.; 0000-0003-3719-9482; 0000-0002-4724-0728; 0000-0001-6234-7788; 33094583; ABH-4817-2020; AAJ-4707-2021; AAI-8822-2021Background and study aims : Gastric cancer (GC) is one of the major causes of cancer-related deaths worldwide. Helicobacter pylori (Hp) plays an important role in gastric carcinogenesis by inducing precancerous changes such as atrophic gastritis (AG) and intestinal metaplasia (IM). In our study, we aim to compare the grade of AG and IM before and after Hp eradication in patients who underwent esophagogastroduodenoscopy (EGD) in our center. Patients and methods : The data of 40.060 patients who underwent EGD for various reasons in our Endoscopy Unit between June 2011 and November 2017 were retrospectively evaluated. The grade of AG and IM before and after Hp eradication of patients meeting the study criteria were compared with each other. In addition, these findings were compared using OLGA and OLGIM staging systems. Results : A total of 175 patients, 89 (50.9%) women and 86 (49.1%) men, were included in the study. The mean age was 55 +/- 12 years. The mean time between two EGD examinations was 38 +/- 14 months. Significant improvement was observed in the grade of AG on corpus and antrum after Hp eradication (P=0.000, P=0.008). In the corpus and antrum, the grade of IM was regressed but this was not significant (P=0.80 and P=0.370 respectively). There was a decrease in OLGA stages after Hp eradication (P=0.000). There was also a reduction in the OLGIM stages, but this was not significant(P=0.341). Conclusion: Our study demonstrates that Hp eradication may reduce the risk of developing GC by providing an improvement in AG and IM which are precancerous changes in GC.Item Effectiveness of two desensitizing products: A 6-month randomized clinical, split-mouth study(2020) Kerimova, Leyla; Kiremitci, Arlin; 33439563Purpose: This randomized controlled clinical trial compared the efficacy of a desensitizer containing calcium phosphate with a two-step self-etch adhesive and placebo over a 6-month period. Methods: 50 subjects aged between 2164 years with a sensitivity score of 6 or higher according to the Visual Analog Scale (VAS) in at least three teeth participated in this study. Teethmate Desensitizer, Clearfil SE Bond 2, and placebo (distilled water) were applied randomly to three teeth of each patient. Recall reviews were performed at baseline, 1 week, 1 month, 3 months, and 6 months after treatment, and the sensitivity scores were assessed by air-blast application. The normality of data was analyzed with Shapiro-Wilk. Since the placebo treatment was successful only in a small number of teeth, the three materials could only be compared 10 minutes after the treatment. Data were analyzed with Wilcoxon Test, Friedman and Dunn post-hoc tests (P= 0.05). Results: Sensitivity decreased significantly after application for each of the three test groups when compared to the pretreatment condition (P< 0.05). There were no significant differences between the Teethmate Desensitizer and Clearfil SE Bond 2, and both materials were more effective than the placebo (P< 0.05).Item How Important Is the Etiology in the Treatment of Epiphora?(2016) Ulusoy, Mahmut Oguz; Kivanc, Sertac Argun; Atakan, Mehmet; Akova-Budak, Berna; 27595013Purpose. There are several etiological factors that cause epiphora, and treatment differs according to the cause. We aimed to evaluate the etiology of epiphora and the treatment modalities of the affected patients. Materials and Methods. Data of patients who were referred to ophthalmology clinics for epiphora were retrospectively analyzed. All patients were evaluated for epiphora etiology, treatment modalities, and duration of complaints, after complete ophthalmologic examination. Results. This study consisted of 163 patients with a mean age of 64.61 +/- 16.52 years (range 1-92 years). Lacrimal system disease (48.4% [79/163]) was the most common cause, followed by ocular surface disease (dry eye/blepharitis) (38.7% [ 63/163]). Among the patients included in this study, 69% (113/163) did not receive any treatment, whereas only 1.8% (3/163) were treated surgically. About 4.3% of the patients (7/163) had a complaint for more than 5 years (p = 0.012) and six of these had chronic dacryocystitis and one had ectropion. Conclusion. Epiphora not only has a negative impact on patients' comfort, but also puts them at risk for probable intraocular operations in the future. Therefore, the wide range of its etiology must be taken into consideration and adequate etiology-specific treatment options must be applied.Item Developmental delays and psychiatric diagnoses are elevated in offspring staying in prisons with their mothers(2018) Kutuk, Meryem Ozlem; Altintas, Ebru; Tufan, Ali Evren; Guler, Gulen; Aslan, Betul; Aytan, Nurgul; Kutuk, Ozgur; 0000-0001-5207-6240; 0000-0001-9854-7220; 0000-0002-2918-7871; 0000-0003-2735-4805; 29382903; AAH-1846-2019; C-5074-2015; AAH-1671-2019; AAI-9626-2021; G-8832-2015The aim of the study was to describe the sociodemographic and clinical features of the mothers and their offspring staying with them in prison. The study was planned as a cross-sectional, single-center study of mothers residing in Tarsus Closed Women's Prison of Turkish Ministry of Justice along with their 0 to 6 years old offspring. Mothers were evaluated via Structured Clinical Interview for DSM-IV Axis I Disorders. A psychologist blind to maternal evaluations applied the Denver Developmental Screening Test II (DII-DST). Children/mothers were also evaluated by a child and adolescent psychiatrist via K-SADS-PL. Twenty-four mothers with a mean age of 29.3 years were included. Most common diagnoses in mothers were nicotine abuse (n = 17, 70.8%), specific phobia (n = 8, 33.3%), alcohol abuse (n = 7, 29.2%) and substance abuse (n = 5, 20.8%). Twenty-six children (53.9% female) were living with their mothers in prison, and the mean age of those was 26.3 months. Results of the D-II-DST were abnormal in 33.3% of the children. Most common diagnoses in children were adjustment disorder (n = 7, 26.9%) separation anxiety disorder (n = 3, 11.5%) and conduct disorder (n = 2, 7.7%). A multi-center study is necessary to reach that neglected/under-served population and address the inter-generational transmission of abuse, neglect, and psychopathology.