Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/11727/4809

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    CNN-Based Severity Prediction Of Neurodegenerative Diseases Using Gait Data
    (2022) Erdas, Cagatay Berke; Sumer, Emre; Kibaroglu, Seda; https://orcid.org/0000-0003-3467-9923; 35111334; AGA-5711-2022
    Neurodegenerative diseases occur because of degeneration in brain cells but can manifest as impairment of motor functions. One of the side effects of this impairment is an abnormality in walking. With the development of sensor technologies and artificial intelligence applications in recent years, the disease severity of patients can be estimated using their gait data. In this way, decision support applications for grading the severity of the disease that the patient suffers in the clinic can be developed. Thus, patients can have treatment methods more suitable for the severity of the disease. The presented research proposes a deep learning-based approach using gait data represented by a Quick Response code to develop an effective and reliable disease severity grading system for neurodegenerative diseases such as amyotrophic lateral sclerosis, Huntington's disease, and Parkinson's disease. The two-dimensional Quick Response data set was created by converting each one-dimensional gait data of the subjects with a novel representation approach to a Quick Response code. This data set was regressed with the convolutional neural network deep learning method, and a solution was sought for the problem of grading disease severity. Further, to demonstrate the success of the results obtained with the novel approach, native machine learning approaches such as Multilayer Perceptron, Random Forest, Extremely Randomized Trees, and K-Nearest Neighbours, and ensemble machine learning methods, such as voting and stacking, were applied on one-dimensional data. Finally, the results obtained on the prediction of disease severity by testing one-dimensional gait data with a convolutional neural network architecture that operates on one-dimensional data were included. The results showed that, in most cases, the two-dimensional convolutional neural network approach performed the best among all methods.
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    Comparison of Different Machine Learning Approaches to Detect Femoral Neck Fractures in X-Ray Images
    (2021) Acici, Koray; Sumer, Emre; Beyaz, Salih; 0000-0002-3821-6419; 0000-0001-8502-9184; 0000-0002-5788-5116; AGA-5711-2022; K-8820-2019
    Femoral neck fractures are a serious health problem, especially in the elderly population. Misdiagnosis leads to improper treatment and adversely affects the quality of life of the patients. On the other hand, when looking from the perspective of orthopedic surgeons, their workload increases during the pandemic, and the rates of correct diagnosis may decrease with fatigue. Therefore, it becomes essential to help healthcare professionals diagnose correctly and facilitate treatment planning. The main purpose of this study is to develop a framework to detect fractured femoral necks in PXRs (Pelvic X-ray, Pelvic Radiographs) while also researching how different machine learning approaches affect different data distributions. Conventional, LBP (Local Binary Patterns), and HOG (Histogram of Gradients) features were extracted manually from gray-level images to feed the canonical machine learning classifiers. Gray-level and three-channel images were used as inputs to extract the features automatically by CNNs (Convolutional Neural Network). LSTMs (Long Short-Term Memory) and BILSTMs (Bidirectional Long Short-Term Memory) were fed by automatically extracted features. Metaheuristic optimization algorithms, GA (Genetic Algorithm) and PSO (Particle Swarm Optimization), were utilized to optimize hyper-parameters such as the number of the feature maps and the size of the filters in the convolutional layers of the CNN architecture. The majority voting was applied to the results of the different classifiers. For the imbalanced dataset, the best performance was achieved by the 2-layer LSTM architecture that used features extracted from the fifth max-pooling layer of the CNN architecture optimized by GA. For the balanced dataset, the best performance was obtained by the CNN architecture optimized by PSO in terms of the Kappa evaluation metric. Although metaheuristic optimization algorithms such as GA and PSO do not guarantee the optimal solution, they can improve the performance on a not extremely imbalanced dataset especially in terms of sensitivity and Kappa evaluation metrics. On the other hand, for a balanced dataset, more reliable results can be obtained without using metaheuristic optimization algorithms but including them can result in an acceptable agreement in terms of the Kappa metric.
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    Neurodegenerative disease detection and severity prediction using deep learning approaches
    (2021) Erdas, Cagatay Berke; Sumer, Emre; Kibaroglu, Seda; 0000-0002-3964-268X; AAJ-2956-2021; AGA-5711-2022
    Neurodegenerative diseases (NDDs) such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and Parkinson's disease (PD) can manifest themselves anatomically by degeneration in the brain as well as motor symptoms. The motor symptoms can affect walking dynamics in a disease-specific fashion; characteristically they disrupt gait. As the severity of the disease increases, walking ability deteriorates. We examined the effect of NDDs such as ALS, HD, and PD on gait and developed a convolutional long short-term memory (ConvLSTM) and threedimensional convolutional learning network (3D CNN)-based approach to detecting neurodegenerative conditions and predicting disease severity.
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    Femoral neck fracture detection in X-ray images using deep learning and genetic algorithm approaches
    (2020) Beyaz, Salih; Acici, Koray; Sumer, Emre; 0000-0002-5788-5116; 32584712; K-8820-2019
    Objectives: This study aims to detect frontal pelvic radiograph femoral neck fracture using deep learning techniques. Patients and methods: This retrospective study was conducted between January 2013 and January 2018. A total of 234 frontal pelvic X-ray images collected from 65 patients (32 males, 33 females; mean age 74.9 years; range, 33 to 89 years) were augmented to 2106 images to achieve a satisfactory dataset. A total of 1,341 images were fractured femoral necks while 765 were non-fractured ones. The proposed convolutional neural network (CNN) architecture contained five blocks, each containing a convolutional layer, batch normalization layer, rectified linear unit, and maximum pooling layer. After the last block, a dropout layer existed with a probability of 0.5. The last three layers of the architecture were a fully connected layer of two classes, a softmax layer and a classification layer that computes cross entropy loss. The training process was terminated after 50 epochs and an Adam Optimizer was used. Learning rate was dropped by a factor of 0.5 on every five epochs. To reduce overfitting, regularization term was added to the weights of the loss function. The training process was repeated for pixel sizes 50x50, 100x100, 200x200, and 400x400. The genetic algorithm (GA) approach was employed to optimize the hyperparameters of the CNN architecture and to minimize the error after testing the model created by the CNN architecture in the training phase. Results: Performance in terms of sensitivity, specificity, accuracy, F1 score, and Cohen's kappa coefficient were evaluated using five-fold cross validation tests. Best performance was obtained when cropped images were rescaled to 50x50 pixels. The kappa metric showed more reliable classifier performance when 50x50 pixels image size was used to feed the CNN. The classifier performance was more reliable according to other image sizes. Sensitivity and specificity rates were computed to be 83% and 73%, respectively. With the inclusion of the GA, this rate increased by 1.6%. The detection rate of fractured bones was found to be 83%. A kappa coefficient of 55% was obtained, indicating an acceptable agreement. Conclusion: This experimental study utilized deep learning techniques in the detection of bone fractures in radiography. Although the dataset was unbalanced, the results can be considered promising. It was observed that use of smaller image size decreases computational cost and provides better results according to evaluation metrics.