Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/11727/4809

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Author: search.filters.author.Karaca, Busra Kubra

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    Detection of multiple sclerosis from photic stimulation EEG signals
    (2021) Karaca, Busra Kubra; Aksahin, Mehmet Feyzi; Ocal, Ruhsen
    Background: Multiple Sclerosis (MS) is characterized as a chronic, autoimmune and inflammatory disease of the central nervous system. Early diagnosis of MS is of great importance for the treatment and course of the disease. In addition to the many methods, cost-effective and non-invasive electroencephalogram signals may contribute to the pre-diagnosis of MS. Objectives: The aim of this paper is to classify male subjects who have MS and who are healthy control using photic stimulation electroencephalogram signals. Methods: Firstly the continuous wavelet transformation (CWT) method was applied to electroencephalogram signals under photic stimulation with 5Hz, 10Hz, 15Hz, 20Hz, and 25Hz frequencies. The sum, maximum, minimum and standard deviation values of absolute CWT coefficients, corresponding to "1-4 Hz" and "4-13 Hz" frequency ranges, were extracted in each stimulation frequency region. The ratios of these values obtained from the frequency ranges "1-4Hz" and "4-13Hz" was decided as features. Finally, various machine learning classifiers were evaluated to test the effectivity of determined features. Results: Consequently, the overall accuracy, sensitivity, specificity and positive predictive value of the proposed algorithm were 80 %, 72.7 %, 88.9 %, and 88.9 %, respectively by using the Ensemble Subspace k-NN classifier algorithm. Conclusions: The results showed how photic stimulation electroencephalogram signals can contribute to the prediagnosis of MS.
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    Comparative Study for Tuberculosis Detection by Using Deep Learning
    (2021) Karaca, Busra Kubra; Guney, Selda; Dengiz, Berna; Agildere, Muhtesem
    Tuberculosis (TB) is an infectious disease which becomes a significant health problem worldwide. Many people have been affected by this disease owing to deficiency of treatment and late or inaccuracy of diagnosis. Therefore, accurate and early diagnosis is the very major solution to checking and preventing the disease. A chest x-ray is a main diagnostic tool used to diagnose tuberculosis. This diagnostic method is limited by the availability of radiologists and the experience and skills of radiologists in reading x-rays. To overcome such a challenge, a computer-aided diagnosis (CAD) system is supposed for the radiologist to interpret chest x-ray images easily. In this study, a CAD system based upon transfer learning is developed for TB detection using Montgomery Country chest x-ray images. We used the VGG16, VGG19, DenseNet121, MobileNet, and InceptionV3 pre-trained CNN models to extract features automatically and used the Support Vector Machine (SVM) classifier to the detection of tuberculosis. Furthermore, data augmentation techniques were applied to boost the performance results. The proposed method performed the highest accuracy of 98.9% and area under the curve (AUC) of 1.00, respectively, with the DenseNet121 on augmented images.
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    Heart sound recording and automatic S1-S2 waves detecting system design
    (2020) Aksahin, Mehmet Feyzi; Oltu, Burcu; Karaca, Busra Kubra
    The second leading cause of death in the world is cardiovascular diseases. Diagnosis of vast majority of cardiovascular diseases is made by listening to heart sounds by specialists (auscultation method). However, since the method of auscultation depends on the experience and hearing ability of the specialist, obtained results can be subjective. Therefore, digitization and visualization of heart sounds enables accurate, rapid and economical diagnosis of cardiovascular diseases, especially heart valve diseases. For this purpose, a device prototype that collects the heart sound from human body and also amplifies, filters, displays and records collected data on digital environment was designed in the first part of this study. In order to test the working accuracy of the designed device, clinical applications were carried out with the permission of the ethics committee and as the result of this application 15 heart sound recordings from 5 different disease groups(mitral insufficiency, mitral-aortic insufficiency, mitral-tricuspid insufficiency, mitral-aortic tricuspid insufficiency and healthy heart sound recordings) were collected.and obtained recordings were examined. The most effective parameter for the diagnosis of heart valve diseases is the location of the S1-S2 heart sounds. For this reason, in the second part of the study, a medical decision support system was established to detect the S1-S2 locations to assist physicians in their diagnosis. In this context, heart sounds are first filtered by discrete wavelet transform. Then, the S1-S2 waves in the filtered signal are made evident by the teager energy operator and rule-based algorithm. As a result, S1-S2 locations in normal and pathological data were detected with 98.67% sensitivity, 97.69% specificity and 98.18% accuracy.