Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
Permanent URI for this collectionhttps://hdl.handle.net/11727/1402
Browse
11 results
Search Results
Item The Relation Between Meal Frequency and Obesity in Adults(2018) Muftuoglu, Selen; Ozdemir, Merve; Saka, Mendane; Ok, Mehtap Akcil; Koseler, Esra; Bayram, Sinem; Yesil, Esen; Kose, Beril; Turker, Perim; Ercan, Aydan; Aksoydan, Emine; Tayfur, Muhittin; Kiziltan, Gul; 0000-0003-1569-7747; AAF-4491-2021; AAX-4714-2021; AAG-6763-2020; AAZ-8170-2020Objective: To determine the relation between meal frequency and obesity in adults. Methods: A cross-sectional study was done among 1829 volunteer (520 men, 1309 women) selected through a multi-stage stratified random sampling method during 2015/2016. A standardized, confidential data collection sheet was used. It included socio-demographic factors, dietary behaviors, anthropometric measurements and energy-macro and micronutrient intakes. Results: The median meal frequency of women and men were 4 and 3, respectively. Approximately 57% of men and 61% of women have skipped meals and 76.8% of them were skipped their lunch. In addition, the individuals whose BMI were under and over 25 kg/m(2) (72.4%, 78.3%, respectively) often skipped lunch. The meal frequency positively correlated with waist to hip ratio in women (p<0.05). Additionally, there were positively significant correlations between meal frequency and saturated fatty acids, fiber, vitamin A, vitamin C, calcium and iron intake (p<0.05). Conclusion: This study indicated that increased meal frequency may have a beneficial effect on micronutrients intakes and some anthropometric measurements among adults.Item The Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Rats(2018) Koseler, Esra; Kiziltan, Gul; Turker, Perim Fatma; Saka, Mendane; Ok, Mehtap Akcil; Bacanli, Didem; Aydos, Tolga Resat; Bayraktar, Nilufer; Ozdemir, Handan; 0000-0002-4254-3711; 0000-0002-1832-9336; 0000-0002-7886-3688; AAZ-8170-2020; AAJ-7279-2020; Y-8758-2018Objective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.Item Effect of Nutrition Education on Diet Quality, Sustainable Nutrition and Eating Behaviors among University Students(2021) Yolcuoglu, Irem Zeynep; Kiziltan, Gul; 34330188Objective Nutrition information is provided by proper nutrition education and nutrition education programs have a direct impact on nutrition knowledge and behavior. This study aims to determine the effect of nutrition education on diet quality, sustainable nutrition and eating behavior. Design Cross-sectional survey. Participants The study was carried out on a total of 204 individuals, 21 males and 183 females, who were studying in the 3rd and 4th grades of Baskent University Faculty of Health Sciences. Main outcome measures Mean Adequacy Ratio (MAR) score calculated with the Nutrient Adequacy Ratio (NAR) was used to evaluate the diet quality. 'Sustainable and Healthy Eating Behaviors Scale' was applied to measure sustainable and healthy eating behaviors. Analysis A questionnaire including personal information and anthropometric measurements of the individuals and a 24-hour dietary recall was taken. Food consumption records were evaluated using the Nutrition Information System. In order to evaluate the quality of the diet, the Mean Adequacy Ratio (MAR) score calculated with the Nutrient Adequacy Ratio (NAR) was used. 'Sustainable and Healthy Eating Behaviors Scale' was applied to measure sustainable and healthy eating behaviors. SPSS 20.0 package program was applied to evaluate the data. Results In the study, 47.5% of the individuals were educated in Nutrition and Dietetics program and 52.5% were in other programs. The diet quality of 44.8% of the individuals studying in the Nutrition and Dietetics program and 56.4% of the individuals studying in the other programs were determined as 'good' according to the MAR levels classification. No significant difference was found in terms of MAR levels of individuals according to the departments they read (p > 0.05). The average score of the 'Healthy and Balanced Nutrition' factor in the scale of sustainable and healthy eating behaviors was higher in individuals who were studying in the Nutrition and Dietetics program. The average scores of 'Seasonal Food' and 'Low Fat' factor were found to be significantly higher in girls studying in the Nutrition and Dietetics program (p < 0.05). Conclusion It was determined that nutrition education is effective on sustainable and healthy eating behaviors. Considering the importance of nutrition education on the health of individuals and sustainable environment, it is of great importance in terms of public health to increase the awareness of the society on this issue.Item Effects of Nutritional Knowledge of Informal Caregivers on Depression and Metabolic Outcomes of Hemodialysis Patients(2021) Kiziltan, Gul; Turker, Perim Fatma; Beyaz, Esra Koseler; Saka, Mendane; Sayin, Cihat Burak; 0000-0001-8287-6572; 34459351; J-3707-2015Chronic renal failure (CRF) makes significant changes in the life of patients and their families. A good family support has a positive effect on successful patients' adaptation to the treatment and compliance with dietary regimen. This study aimed to examine the effects of nutritional knowledge of informal caregivers on depression and metabolic outcomes of hemodialysis patients. This was a cross-sectional study conducted at Baskent University Hemodialysis Center with 116 hemodialysis patients and their informal caregivers. Findings revealed that the caregivers who were the couple of the patients had the highest nutritional knowledge level than the other caregivers (p < .05). The postgraduate caregivers were more likely to have high nutritional knowledge level than the others (p < .05). The inflammation marker of the patients was significantly lower in the group of caregivers with higher level (T3 group) of nutritional knowledge than the others (p < .05). The mean CES-D scores were also more likely to be low in T3 group than in the others (p < .05). These findings highlight that the nutritional knowledge of caregivers of hemodialysis patients may have an additional benefit on patients' nutritional management and metabolic outcomes.Item Association of the Relationship Between Nutritional Status and Certain Biochemical Parameters in Obese Children(2021) Ozcelik-Ersu, Dilek; Kiziltan, GulThe prevalence of childhood obesity is increasing globally. Adiposity is more concentrated in subcutaneous tissue in women and visceral fat tissue in men. Abdominal obesity is more commonly associated with metabolic diseases in men. The results showed that the mean BMIz scores of boys was higher than girls, but total body fat was lower than girls. Total body fat free mass, water and muscle mass were higher in boys than girls. It was determined that children aged 10-17 years consumed fatty and sugary snacks and sugary drinks at school. Food consumption containing the carbohydrate, fat, saturated fat and cholesterol were higher in boys than girls. As a result, it was thought that it would be more beneficial and reliable to use anthropometric methods showing body composition together with BMI zscore while evaluating body weight in adolescents. While nutritional counseling, it may be beneficial to consider that the energy and nutrient requirements of male adolescent individuals and their daily food consumption are higher than girls. When the results of the study are evaluated, we mention that it would be appropriate to evaluate girls more carefully in terms of iron deficiency anemia and diseases such as insulin resistance and diabetes.Item Combined Therapy with Probiotic VSL#3 and Omega-3 Fatty Acids Attenuates Colonic Injury and Inflammation in Chronic DNBS-induced Colitis in Mice(2021) Ilktac, Havvanur Yoldas; Kiziltan, Gul; Lanpir, Asli Devrim; Ozansoy, Mehmet; Gunal, Mehmet Y.; Togay, Sine Ozmen; Keskin, Ilknur; Ozdemir, Ekrem M.; Kilic, UlkanInflammatory bowel disease (IBD) is a progressive chronic inflammatory disease affecting the gastrointestinal tract with a chronic relapsing and remitting disease course. While there are a number of therapeutic strategies available to treat IBD, a definitive treatment still hasn't been defined, leading to alternative treatment options including nutritional support. Herein, we planned to investigate the combined impact of probiotics and omega-3 (omega-3) fatty acids on inflammatory response and intestinal epithelium in chronic colitis induced by 2,4-Dinitrobenzenesulfonic acid (DNBS). Fifty BALB/c mice were randomly divided into five groups: non-colitis control, colitis with no treatment applied (control colitis), colitis treated with probiotics (VSL#3), colitis treated with omega-3, and colitis treated with both VSL#3 and omega-3. Colitis was induced by intrarectal administration of 2,4-Dinitrobenzenesulfonic acid (DNBS) in all groups but the non-colitis control group. Ten days after the DNBS period, phosphate-buffered saline (for both the non-colitis control and colitis control groups), VSL#3, omega-3, or VSL#3 + omega-3 treatments were administered intragastrically to their respective groups for 10 days. By analyzing the colonic expression of interleukin IL-6, IL-10, and IL-17A, and interferon gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) levels, results revealed that levels of IFN-gamma IL-17, and TNF-alpha were significantly higher in the control colitis group when compared with the other groups. The control colitis, colitis +VSL#3, and colitis + omega-3 groups exhibited higher scores of microscopic damage compared to the non-colitis control and colitis + VSL#3 + omega-3 groups. The closest histological image to the non-colitis control group was presented in the colitis + VSL#3 + omega-3 group. The findings indicate that the combined effect of probiotics and omega-3 fatty acids might have a protective effect against colon injury and inflammation by creating synergistic effects. However, more research is needed to understand the exact mechanism of this synergistic effect and to examine how this therapeutic approach can be used in inflammatory bowel diseases.Item Challenges and needs of informal caregivers in elderly care: Qualitative research in four European countries, the TRACE project(2020) Akgun-Citak, Ebru; Attepe-Ozden, Seda; Kav, Sultan; Acar, Sema; Aksoydan, Emine; Altintas, Atahan; Aytar, Aydan; Baskici, Cigdem; Kiziltan, Gul; 0000-0003-0361-7498; 0000-0002-0484-4687; 31756568; V-9745-2019; ABD-7108-2020Background: Providing informal care may affects caregivers' life in different ways. Determining the needs of caregivers and supporting them can improve both the quality of life of the caregivers, as well as the elderly they take care of. Objective: To explore the experiences and needs of the informal caregivers in four countries. Design: Qualitative research method was used in the study. Methods: The qualitative data was collected through focus groups and individual interviews between December 2016-May 2017. In all countries interviews were conducted in the mother language of the informants. Informants of the qualitative research were adult people who take primary care of an individual with chronic diseases, aged 65 years or older. Data were collected from 72 informal caregivers from four European countries. Inductive content analysis was performed. Results: Informal caregivers identified 2 themes, 5 subthemes, 19 categories and 7 subtcategories. The themes highlighted two major issues: informal caregiver's challenges and needs related to the management of care of elderly and caregivers' personal needs. Conclusion: The important and charming results of the present study are, difficulties of managing caregiver's own life, and coping with emotions are common in four countries. Identifying challenges and needs of informal caregivers enable healthcare professionals to develop care strategies and plan interventions focused to support and help to reduce the burden of care for elderly with chronic diseases.Item Effects of reproductive and sociodemographic factors on obesity in Turkish women: a pilot study(2019) Bayram, Sinem; Koseler, Esra; Kiziltan, Gul; Ok, Mebtap Akcil; Yesil, Esen; Kose, Beril; Ozdemir, Merve; Muftuoglu, Selen; Saka, Mendane; Aksoydan, Emine; Tayfur, Muhittin; Turker, Perim Fatma; Ercan, Aydan; 0000-0003-1569-7747; 0000-0002-4254-3711; AAF-4491-2021; AAG-6763-2020Background and aim: Obesity has become a global epidemic. The current research aimed to determine sociodemographic and reproductive predictors of obesity among Turkish women. Materials and methods: Eligible subjects (n:833) were 40-64 years-old women living in Turkey. A questionnaire consisted of questions about sociodemographic and reproductive factors and the International Physical Activity Questionnaire were applied to participants by face to face interviews. Multivariate logistic regression examined the risk of being obese with a range of sociodemographic and reproductive factors. All analyses were performed with SPSS software (version 17.0; SPSS, Chicago, Ill., USA). Results: The mean BMI of women aged 51-64 years was 30.59 +/- 6.35 kg/m(2). After adjustments for all other variables, increased obesity risk remained significant in women who had two children, housewifes, minimum active ones, ex smokers and had less than high school education. For multiple regression analysis sociodemographic factors from the bivariate analyses were entered, controlling for menarch age, menopausal age, hormone RT, parity, number of stillbirth, abortion. There was significant association between family income, occupation, education and BMI. Conclusion. In summary these findings showed comparable patterns of association of sociodemographic and reproductive factors with obesity in Turkey. Specific healthy lifestyle counseling is important for decreasing obesity in childbearing age women.Item Effect of weight loss diets on biochemical parameters and anthropometric measurements in prolactinoma patients(2019) Yesil, Esen; Kiziltan, Gul; Anil, Cuneyd; Ok, Mehtap Akcil; Bayraktar, Nilufer; AAZ-8170-2020Background: The aims of this study were to determine the effect of weight loss on biochemical parameters and anthropometric measurements in prolactinoma patients and to evaluate the effectiveness of weight loss diet along with medical treatment. Methods: Twenty-two patients with prolactinoma were divided into two groups and one of the groups was applied weight loss diet (diet group) while the other group was diet free (control group). Each participant was interviewed using a structured questionnaire. The biochemical parameters (fasting plasma glucose, fasting plasma insulin, prolactin, leptin, TSH, T4, cortisol, HbA1c, AST, ALT and blood lipids) of participants were analyzed and anthropometric measurements were taken. Results: There was a significant change in mean BMI after treatment in diet group (p=0.000). The mean level of serum prolactin decreased from 45.1 +/- 31.63 ng/dL at baseline to 12.6 +/- 8.19 ng/dL after three months in diet group (p=0.006). Despite there being no statistically significant difference between diet and control group in terms of baseline level of prolactin measurement (p=0.800), statistically significant difference between the two groups in terms of final level of prolactin measurement (p=0.027) was observed. There was a significant change in mean level of leptin after treatment in diet group (p=0.001). Conclusions: In addition to medical treatment, weight loss diets sped up the healing process for hyperprolactinemia and the reduction in body weight had positive effects on the metabolic profiles of prolactinoma patients.Item The effect of nutrition theraphy on oxidative stress, inflammation, glycemic control in type 2 diabetes patients(2019) Colak, Gozde Aritici; Kiziltan, GulAims: Type 2 diabetes mellitus is a metabolism disease which is seen frequently among adult population in Turkey. The aim of this study was to determine the medical nutrition theraphy effect on oxidative stress, inflammation, glycemic control in type 2 diabetes patients. Methods: An interventional study was carried on 35 type 2 diabetes ages between 20-65 years old at the Department of Endocrinology of Baskent University Istanbul Hospital in 2015. In 3 month period a personal nutrition theraphy was applied. Biochemical parameters, anthropometric measurements and body analysis were also determined. The three day food consumption and biochemical parameters were requested at the beginning and at the end of the study. Results: When the impact of the blood values of the new medical nutrition theraphy which the patients practiced during the first visit and the follow up visit were compared; it was seen that there was a significant decrease on fasting plasma glucose, fasting insulin, HbA1c, CRP, TG and MDA values (p<0.05). The mean diabetic age of the patients was 7.63 +/- 6.22 years. When diabetic age of the patients was increased, there was a positive correlation between the fasting plasma glucose and HbA1c values (p<0.05). Conclusions: Type 2 diabetes patients were evaluated 3 month of medical nutrition theraphy and it was seen that the personal medical nutritional theraphy contributed to providing glisemic control and decreasing oxidative stress and inflammation.