Sağlık Hizmetleri Meslek Yüksekokulu / Vocational School of Health Services
Permanent URI for this collectionhttps://hdl.handle.net/11727/3080
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Item Measurement and Analysis of Electromagnetic Fields of Mobile Communication Antennas in Turkish Republic of Northern Cyprus(2019) Bulut, Ayse; Firlarer, ArzuItem Dedifferentiated Epithelial-Myoepithelial Carcinoma of the Parapharyngeal Area: Case Report(2016) Akcay, F. Yilmaz; Canpolat, T.; Erkan, A. N.; Borcek, P.; Gunhan, O.; 0000-0001-7138-1400; AAK-8107-2021; H-1063-2019Item The Effect of Thyroid Dysfunction on Nesfatin-1 And Adiponectin Levels in Rats(2017) Atici, Emine; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim; Menevse, Esma; 0000-0003-2461-1212; 0000-0002-5477-5667; 0000-0002-6547-4798; 28796641; AAL-5444-2020; ABA-7831-2020; AAG-5865-2019Background: Changes in thyroid hormone concentrations may affect adiponectin concentrations through various mechanisms. A molecule released primarily from the fat cells adiposities; adiponectin has important effects on the regulation of body weight. Aim: The present study aimed to explore the effects of experimental thyroid dysfunction and its treatment on nesfatin-1 and adiponectin levels in rats. Methods: The study included 40 adult male Sprague-Dawley rats which were grouped as follows: (1) control; (2) hypothyroidism [hypothyroidism was induced by intraperitoneal injection of 10 mg/kg/day propylthiouracil (PTU) for 3 weeks]; (3) hypothyroidism + thyroxine group [after hypothyroidism was induced by 2-week PTU injection, they were treated with high-dose L-thyroxine (1.5 mg/kg/day) for 1 week]; (4) hyperthyroidism [hyperthyroidism was induced by 3-weeks' thyroxine injection (0.3 mg/kg/day)]; (5) hyperthyroidism + PTU (after hyperthyroidism was induced by 2-weeks' thyroxine injection, the animals were given 10 mg/kg/day PTU for 1 week). Blood samples taken at the end of the study were analyzed to measure nesfatin-1 and adiponectin levels. Results: It was found that nesfatin-1 levels increased in hypothyroidism, while adiponectin levels decreased (p < 0.001). In experimental hyperthyroidism, on the other hand, both nesfatin-1 and adiponectin levels were found significantly elevated (p < 0.001). Conclusion: The results of the study indicate that nesfatin-1 and adiponectin levels were modified considerably in hypo- and hyperthyroidism, whereas with the restoration of the thyroid function, modified hormone levels went back to normal.Item Evaluation of Hemodialysis Patients in Terms of Activities of Daily Living, Disability, Depression and Comorbidity(2017) Turgay, Gulay; Tutal, Emre; Sezer, SirenOBJECTIVE: This study was conducted to evaluate the hemodialysis patients in terms of activities of daily living (ADLs), disability, depression and comorbidity. MATERIAL and METHODS: The population of this cross-sectional study included 220 patients undergoing treatment at a dialysis center between June-August 2016. The study sample however was comprised of 144 patients who were 50 years old and above, had been undergoing hemodialysis treatment for at least six months and who agreed to participate in the research. The data was collected using the Patient Identification Form, the Katz Activities of Daily Living Scale, Lawton and Brody Instrumental Activities of Daily Living Scale, Brief Disability Questionnaire, Charlson Comorbidity Score and Beck Depression Inventory. RESULTS: The patients were divided into two groups: the 50-64 years age group and the 65-plus age group. The patients in the first group were found to have an Activities of Daily Living Scale score of 17.28 +/- 1.45, Instrumental Activities of Daily Living Scale score of 19.98 +/- 3.02, and a Brief Disability Questionnaire score of 7.42 +/- 3.99 whereas the patients in the second group were found to have score of 15.73 +/- 2.53, 17.29 +/- 3.43 and 10.7 +/- 4.18 respectively. CONCLUSION: Hemodialysis and age progression leads to dependency of patients at varying levels while they maintain their activities of daily living.Item Home Application by Hemodialysis Patients for Hypertension Management(2017) Gokdogan, Feray; Kes, Duygu; Turgay, Gulay; Tuna, DonduOBJECTIVE: This study aimed to determine home application by hemodialysis patients for hypertension management. MATERIAL and METHODS: The population of the descriptive study included a total of 279 patients who were treated at the hemodialysis centers of two state hospitals, one private hospital and one training and research hospital situated within Karabuk province. A total of 120 patients who were over 18 years of age, had hypertension, could communicate, and whose clinic state were stable, who did not have any mental and psychiatric disorder and who accepted to participate in the research voluntarily were included in the sample. RESULTS: It was determined that 59.2% of the patients who participated in the study did not measure their blood pressures at home regularly; 44.6% did not take their medication regularly and did not know the name and dosages of their medication (60.7% and 64.3% respectively); 73.2% had stopped taking medication without the physician's knowledge; 85% used salt in meals; and 70.8% and 46.7% respectively did not comply with the liquid limitation. CONCLUSION: It is important to reveal the effects of a nursing care approach for supporting hypertension self-management at home of our patients based on their individual characteristics through studies focusing on regular training, monitoring and providing consultancy services.Item Co-Culture of Rat Luteal Cells with Islet Cells Enhances Islet Viability and Revascularization(2018) Boyuk, Gulbahar; Yigit, A. Arzu; Aydogan, Ilkay; 0000-0001-5837-6877; 30187177; AAD-1857-2020; C-2636-2017Islet cell transplantation is a major treatment strategy for type I diabetes, and has proven to be effective for maintaining glucose homeostasis. However, this treatment requires an extended period of immunosuppression to prevent rejection and recurrent transplantation to maintain function. Thus, to enhance the properties of transplanted islet cells, we examined the effect of the co-culture of luteal cells, which secrete progesterone, on islet cell viability, functionality, and revascularization. It was found that islet viability and functionality were higher in the co-cultured group than in single cultures of islets at 48 and 96 h, in parallel with increased progesterone and vascular endothelial growth factor (VEGF) secretion from luteal cells. In the co-culture groups, VEGF levels at 48 and 96 h and CD31 levels at 48 h were significantly higher than those in the islet groups (p < 0.001 and p < 0.05, respectively), and basic fibroblast growth factor (bFGF) levels were increased at 96 h (p < 0.001). Thus, co-culture with luteal cells may increase islet vascularity by enhancing VEGF and bFGF levels for up to 96 h, which could help to markedly increase the pre-transplantation time to allow for effective immunosuppression therapy. This method may also promote islet cell viability and functionality. Progesterone and angiogenic factors secreted from luteal cells may be responsible for these positive effects.Item Investigation of the Achievability of Stem Cells Derived from Luteal Cells in Rats(2018) Yigit, Ayse Arzu; Orscelik, Emine Umran; Boyuk, Gulbahar; Tiryaki, Meral; Pinarli, Ferda Alparslan; 0000-0002-3453-2967; AAC-4677-2021Item Can Luteal Cell Co-Cultures be an Alternative for Reduction of the Immunorejection in Islet Transplants?(2018) Boyuk, Gulbahar; Yigit, A. Arzu; 0000-0002-3453-2967; 0000-0001-5837-6877; AAC-4677-2021; C-2636-2017Item Biyokimya(2018) Güven, AyselItem Resonant frequency shifts related to the elastic constants near the alpha-beta transition in quartz(2019) Yurtseven, H.; Ates, S.The resonant frequency shifts of vibrational modes are related to the elastic constants at various temperatures for the alpha-beta transition in quartz (T-c = 573.0 degrees C for alpha-quartz and 574.3 degrees C for beta-quartz). This correlation is constructed on the basis of the spectroscopic modifications of the Pippard relations near the alpha-beta transition in quartz by using the observed data from the literature. Our results indicate that the elastic properties can be described from the spectroscopic parameters (frequency shifts) as we have studied here for the alpha-beta transition in quartz. Using those relations, elastic constants can also be obtained from the frequency shifts near the phase transitions of various crystalline systems. (C) 2018 Elsevier B.V. All rights reserved.