Sağlık Hizmetleri Meslek Yüksekokulu / Vocational School of Health Services
Permanent URI for this collectionhttps://hdl.handle.net/11727/3080
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Item The influence of vitamin d3 treatment on the risk of development of acute rejection, epithelial-mesenchymal transition (EMT), and interstitial fibrosis among pediatric renal transplant patients(2019) Ozdemir, B. Handan; Baskin, Esra; Ozdemir, F. Nurhan; Akcay, Eda Yilmaz; Moray, Gokhan; Haberal, Mehmet; 0000-0003-4361-8508; B-5785-2018Item The importance of age and CD4/CD8 ratio on the presenting time and the prognosis of the polyoma virus associated nephropathy (PVAN) after renal transplantation(2019) Ozdemir, B. Handan; Ozdemir, F. Nurhan; Baskin, Esra; Atilgan, Alev Ok; Moray, Gokhan; Haberal, Mehmet; 0000-0003-4361-8508; B-5785-2018Item EFFECT OF LIVER TRANSPLANTATION ON NEUROLOGICAL MANIFESTATIONS AND BRAIN MAGNETIC RESONANCE IMAGING FINDINGS IN WILSON DISEASE(2019) Soy, Ebru H. Ayvazoglu; Ocal, Ruhsen; Benli, Sibel; Donmez, Fuldem; Agildere, Muhtesem; Ocal, Serkan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019; AAB-5802-2020Item CYTOMEGALOVIRUS (CMV) INFECTION INDUCES AN ANGIOGENIC RESPONSE THROUGH HEPATIC STELLATE CELLS (HSCS) AND LEADS TO EARLY POST-TRANSPLANT LIVER FIBROSIS (LF) AND POOR GRAFT SURVIVAL(2019) Ozdemir, B. Handan; Ozgun, Gonca; Soy, Ebru H. Ayvazoglu; Haberal, Nihan; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019Item ENDOTHELIAL CELL CYTOSKELETON REARRANGEMENT (ECCSKR) AND ENDOTHELIAL TO MESENCHYMAL TRANSITION (ENDOMT) IN LIVER ALLOGRAFTS FOLLOWING ACUTE REJECTION: IT'S SIGNIFICANCE ON THE LIVER FIBROSIS(2019) Ozdemir, B. Handan; Ozgul, Gonca; Soy, Ebru H. Ayvazoglu; Akdur, Aydincan; Haberal, Nihan; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019Item THE IMPACT OF INVERTED RENAL CD4/CD8 RATIO IN THE FIRST 3-MONTH BIOPSIES POST-TRANSPLANT ON THE DEVELOPMENT OF TRANSPLANT GLOMERULOPATHY AND VASCULOPATHY IN RENAL ALLOGRAFTS(2019) Ozdemir, Handan B.; Ozdemir, Nurhan F.; Atilgan, Alev Ok; Akcay, Eda; Kirna, Mahir; Haberal, Mehmet; AAH-9198-2019Item WHAT IS THE ROLE OF ENDOTHELIAL-TO-MESENCHYMAL TRANSITION (ENDOMT) OF RENAL CAPILLARIES ON THE RENAL OUTCOME BOTH IN ISOLATED TRANSPLANT GLOMERULOPATHY AND CHRONIC ANTIBODY-MEDIATED REJECTION (CAMR)(2019) Ozdemir, B. Handan; Ozdemir, F. Nurhan; Akdur, Aydincan; Kirnap, Mahir; Moray, Gokhan; Haberal, Mehmet; AAH-9198-2019Item Effect of Graft Weight to Recipient Body Weight Ratio on Hemodynamic and Metabolic Parameters in Pediatric Liver Transplant: A Retrospective Analysis(2017) Haberal, Mehmet; Ersoy, Zeynep; Kaplan, Serife; Ozdemirkan, Aycan; Torgay, Adnan; Arslan, Gulnaz; Pirat, Arash; 0000-0003-0767-1088; 0000-0002-6829-3300; 0000-0002-3462-7632; 28260433; AAF-3066-2021; AAJ-5221-2021; AAJ-8097-2021; AAH-7003-2019Objectives: To analyze how graft-weight-to-body-weight ratio in pediatric liver transplant affects intraoperative and early postoperative hemodynamic and metabolic parameters. Materials and Methods: We reviewed data from 130 children who underwent liver transplant between 2005 and 2015. Recipients were divided into 2 groups: those with a graft weight to body weight ratio > 4% (large for size) and those with a ratio <= 4% (normal for size). Data included demographics, preoperative laboratory findings, intraoperative metabolic and hemodynamic parameters, and intensive care follow-up parameters. Results: Patients in the large-graft-for-size group (>4%) received more colloid solution (57.7 +/- 20.1 mL/kg vs 45.1 +/- 21.9 mL/kg; P = .08) and higher doses of furosemide (0.7 +/- 0.6 mg/kg vs 0.4 +/- 0.7 mg/kg; P = .018). They had lower mean pH (7.1 +/- 0.1 vs 7.2 +/- 0.1; P = .004) and PO2 (115.4 +/- 44.6 mm Hg vs 147.6 +/- 49.3 mm Hg; P = .004) values, higher blood glucose values (352.8 +/- 96.9 mg/dL vs 262.8 +/- 88.2 mg/dL; P < .001), and lower mean body temperature (34.8 +/- 0.7 degrees C vs 35.2 +/- 0.6 degrees C; P = .016) during the neohepatic phase. They received more blood transfusions during both the anhepatic (30.3 +/- 24.3 mL/kg vs 18.8 +/- 21.8 mL/kg; P = .013) and neohepatic (17.7 +/- 20.4 mL/kg vs 10.3 +/- 15.5 mL/kg; P = .031) phases and more fresh frozen plasma (13.6 +/- 17.6 mL/kg vs 6.2 +/- 10.2 mL/kg; P = .012) during the neohepatic phase. They also were more likely to be hypotensive (P < .05) and to receive norepinephrine infusion more often (44% vs 22%; P < .05) intra-operatively. More patients in this group were mechanically ventilated in the intensive care unit (56% vs 31%; P = .035). There were no significant differences between the groups in postoperative acute renal dysfunction, graft rejection or loss, infections, length of intensive care stay, and mortality (P > .05). Conclusions: High graft weight-to-body-weight ratio is associated with adverse metabolic and hemodynamic changes during the intraoperative and early postoperative periods. These results emphasize the importance of using an appropriately sized graft in liver transplant.