Sağlık Hizmetleri Meslek Yüksekokulu / Vocational School of Health Services

Permanent URI for this collectionhttps://hdl.handle.net/11727/3080

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Author: search.filters.author.Atici, Emine

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    The Effect of Thyroid Dysfunction on Nesfatin-1 And Adiponectin Levels in Rats
    (2017) Atici, Emine; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim; Menevse, Esma; 0000-0003-2461-1212; 0000-0002-5477-5667; 0000-0002-6547-4798; 28796641; AAL-5444-2020; ABA-7831-2020; AAG-5865-2019
    Background: Changes in thyroid hormone concentrations may affect adiponectin concentrations through various mechanisms. A molecule released primarily from the fat cells adiposities; adiponectin has important effects on the regulation of body weight. Aim: The present study aimed to explore the effects of experimental thyroid dysfunction and its treatment on nesfatin-1 and adiponectin levels in rats. Methods: The study included 40 adult male Sprague-Dawley rats which were grouped as follows: (1) control; (2) hypothyroidism [hypothyroidism was induced by intraperitoneal injection of 10 mg/kg/day propylthiouracil (PTU) for 3 weeks]; (3) hypothyroidism + thyroxine group [after hypothyroidism was induced by 2-week PTU injection, they were treated with high-dose L-thyroxine (1.5 mg/kg/day) for 1 week]; (4) hyperthyroidism [hyperthyroidism was induced by 3-weeks' thyroxine injection (0.3 mg/kg/day)]; (5) hyperthyroidism + PTU (after hyperthyroidism was induced by 2-weeks' thyroxine injection, the animals were given 10 mg/kg/day PTU for 1 week). Blood samples taken at the end of the study were analyzed to measure nesfatin-1 and adiponectin levels. Results: It was found that nesfatin-1 levels increased in hypothyroidism, while adiponectin levels decreased (p < 0.001). In experimental hyperthyroidism, on the other hand, both nesfatin-1 and adiponectin levels were found significantly elevated (p < 0.001). Conclusion: The results of the study indicate that nesfatin-1 and adiponectin levels were modified considerably in hypo- and hyperthyroidism, whereas with the restoration of the thyroid function, modified hormone levels went back to normal.
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    EFFECTS OF KINESIO TAPING ON POSTURAL STABILITY IN YOUNG SOCCER PLAYERS
    (2019) Gulsen, Mustafa; Pekyavas, Niahn Ozunlu; Atici, Emine; Sahin, Fatma Nese; Guler, Ozkan
    Background: This study aims to investigate the effects of Kinesio Taping on postural stability in young soccer players. Methods: 62 volunteer soccer players from Cayyolu Sports Club were included in our study. Players were randomly allocated into two groups; a Kinesio taping (KT) (n=31), and a control group (n = 31). KT application including gastrocnemius and quadriceps femoris muscle facilitation techniques were applied to the first group. The second group was set as the control group and no application was made. Sociodemographic characteristics, postural stability and thermographic assessment were evaluated prior to and after the application of the Kinesio Taping. All the statistical analyses were set a priori at an alpha level of p<0.05. The tests for homogeneity (Levene's test) and normality (Shapiro-Wilk) were used to determine the appropriate statistical methods to apply for comparison between the groups. According to the test results, the parametric paired sample T-test was used to compare between baseline and post-treatment within a group, while independent sample T-test for equality of means was used for comparison between the groups. Results: No statistically significant differences were observed between the groups at baseline regarding age, body mass index, skin temperature and postural stability (p > 0.05). Statistically significant differences were found in all the assessed parameters in both Kinesio Taping and control groups (all p<0.05) except thermal imaging of dominant gastrocnemius muscle results (p=0.668) after the Kinesio application. Statistically significant differences were found in all parameters across groups (all p<0.05). Conclusions: Kinesio Taping may increase postural stability and decrease the risk of injury. According to thermal imaging assessments, both quadriceps and gastrocnemius muscles may be active in maintaining postural stability. As the decreasing risk of injury is very important for young soccer players, our results may show a preventive measure for sports physiotherapists working on soccer fields.