Browsing by Author "Yavuz, Demet"

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Acute Renal Failure and Its Impact on Survival Following Cardiac Transplantation
(2016) Sezer, Siren; Yavuz, Demet; Canoz, Mujdat Batur; Altunoglu, Alparslan; Sezgin, Atilla; Arat, Zubeyde; Ozdemir Acar, Fatma Nurhan; Haberal, Mehmet; 0000-0002-4082-6320; 0000-0002-3462-7632; ABG-9980-2021; AAJ-8097-2021
OBJECTIVE: We evaluated the incidence and risk factors for acute renal failure (ARF) and also the associated hazard of death in recipients of cardiac transplants. MATERIAL and MET HODS: We included 25 patients in the study; 18 patients developed ARF (72%) and underwent continuous venovenous hemodiafiltration (Group I) and 7 patients had stable renal function (28%) (Group II). We retrospectively retrieved demographic variables; clinical, perioperative, postoperative complications and echocardiographic data; and biochemical parameters at the time of the surgery and six months later. RESULTS: Cumulative survival was 72.2% after 6 months, 64.2% after 24 months, and 51.4% after 32 months for Group I and 50% after 32 months for Group II (p> 0.05). A total of 8 patients died (32%); 1 (5.5%) from Group I and 7 (87.5%) from Group II. Risk factors for ARF were preoperative serum BUN, creatinine levels, and cardiopulmonary bypass time (p< 0.05). Only one patient underwent chronic hemodialysis because of chronic renal dysfunction in Group I while there was no such patient in group II. CONCLUSION: Preoperative serum BUN, creatinine value, and cardioopulmonary bypass time were found to be risk factors for ARF after cardiac transplantation. Postoperative renal dysfunction did not affect long-term renal function and survival.
Depression, Inflammation, and Social Support in Hemodialysis Patients
(2015) Yavuz, Rahman; Yavuz, Demet; Altunoglu, Alparslan; Canoz, Mujdat Batur; Sezer, Siren; Yalcin, Bektas Murat; Demirag, Mehmet Derya
Aim: Depression and inflammation are common in patients with end-stage renal disease (ESRD). In our study, we aimed to investigate the relationship between depression, inflammation and social support. Material and Method: Accordingly. 137 patients were enrolled. We used Beck Depression Inventory (BDI) and Multidimensional Scale of Perceived Social Support (MSPSS) and Malnutrition Inflammation Score (MIS) in all patients. Results: BDI, MSPSS and MISS were 15.9 +/- 9.5,60.5 +/- 15.1,7.8 +/- 2.9 respectively. The patients were divided into two groups with respect to BDI scores: patients with depression (BDI score >= 7, n=55, 40.2%) and patients without depression (BDI score< 17.0 =82, 59.8%). In depressive patients, the majority were female (58%) and lived alone (97%). The weekly erythropoietin dose and CRP levels were higher in patients with depression than in patients without depression and this difference did not reach statistical significance (p>0.05). MIS scores were higher in patients with depression (10.5 +/- 1.8) than in patients without depression (6 +/- 2.2) (p<0.001). Patients with depression (57.3 +/- 1 7.91 had lower MSPSS scores than patients without depression (62.7 +/- 12.5) (p<0.05). There was positive correlation between BDI and MIS, while negative correlation was observed between BDI and MSPSS. In the multivariate linear regression analysis (gender, BUN, albumin, MIS and MSPSS), depression was independently associated with MIS (beta=0.60, t=9.9 p<0.001) and MSPSS (beta=-0.37, t=-6.2 p<0.001). Discussion: Hemodialysis patients needed more social and psychological support. They had higher inflammation and lower social support that associated with the presence of depression, although large-scale studies are needed to confirm our results.
Free Triiodothyronine in Hemodialysis Patients Link With Malnutrition and Inflammation
(2014) Yavuz, Demet; Sezer, Siren; Yavuz, Rahman; Canoz, Mujdat Batur; Altinoglu, Alpaslan; Elsurer, Rengin; Arat, Zubeyde; Ozdemir, Fatma Nurhan; https://orcid.org/0000-0002-4082-6320; https://orcid.org/0000-0002-7326-8388; https://orcid.org/0000-0002-5682-0943; 24878944; ABG-9980-2021; JYQ-2550-2024; AAK-1697-2021
Introduction. Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases. There is lack of data about the link between FT3 levels and malnutrition and inflammation in hemodialysis patients. The objective of the present study was to investigate the link between FT3 and malnutrition and inflammation in hemodialysis patients. Materials and Methods. A total of 84 patients were included in the study (38 men and 46 women; mean age, 56.2 +/- 14.8 years; hemodialysis duration, 95.72 +/- 10.35 months). Serum FT3, free thyroxin, and thyroid-stimulating hormone concentrations were determined. Demographic data and laboratory values were evaluated. Patients' comorbidity status was determined using the Charlson Comorbidity Index (CCI), and malnutrition-inflammation status was determined by Malnutrition-Inflammation Score (MIS). Results. Serum FT3 concentration inversely correlated with age (r = -0.328, P =.002), CCI (r = -0.591, P < .001), C-reactive protein (r = -0.299, P =.01), and MIS (r = -0.671, P < .001), and positively correlated with serum albumin (r = 0.389, P < .001). In multivariate linear regression analysis, FT3 was independently associated with MIS (beta, -0.14; 95% confidence interval, -0.175 to 0.063, P = .003), adjusted for CCI, C-reactive protein level, serum albumin level, and MIS. Conclusions. The results of this study indicate that FT3 is negatively correlated with inflammatory markers, namely C-reactive protein, and it is independently related with MIS in hemodialysis patients. Therefore, we suggest that FT3 can be accepted as an inflammatory marker in hemodialysis patients.
Relationship Between Inflammation, Sex Hormone Profile and Sexual Dysfunction in Female Patients Receiving Different Types of Renal Replacement Therapy
(2014) Altunoglu, Alpaslan; Yavuz, Demet; Canoz, Mujdat Batur; Yavuz, Rahman; Karakas, Latife Atasoy; Bayraktar, Nilufer; Colak, Turan; Sezer, Siren; Ozdemir, Fatma Nurhan; Haberal, Mehmet; https://orcid.org/0000-0002-4082-6320; https://orcid.org/0000-0001-7369-5470; https://orcid.org/0000-0002-7886-3688; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-7326-8388; https://orcid.org/0000-0002-5682-0943; https://orcid.org/0000-0002-3462-7632; ABG-9980-2021; AEY-5060-2022; Y-8758-2018; AAJ-8554-2021; JYQ-2550-2024; AAK-1697-2021; AAJ-8097-2021