Browsing by Author "Somay, Efsun"
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Item Comment on "Predictors of Prolonged Teatment Time Intervals in Oral Cavity Cancer"(ORAL ONCOLOGY, 2024-01) Topkan, Erkan; Somay, Efsun; Selek, UgurItem Comment on: Incidence Rate of Osteonecrosis of Jaw After Cancer Treated with Bisphosphonates and Denosumab: A Systematic Review and Meta-Analysis(SPECIAL CARE IN DENTISTRY, 2024) Somay, EfsunItem Comment on: Intensity Modulated Radiotherapy in Head and Neck Cancer: Initial Experience of the First Treated Cases from North-East India(2023) Topkan, Erkan; Somay, Efsun; Selek, Ugur; 0000-0001-8251-6913; 38187854; AAG-2213-2021; O-5474-2014Item Comment on: Long-Term Effects of Chemotherapy and Radiation Received During Early Childhood on The Developing Dentition of Pediatric Cancer Patients(SPECIAL CARE IN DENTISTRY, 2024) Somay, Efsun; Topkan, Erkan; Selek, UgurItem Comment on: Osteoradionecrosis after postoperative radiotherapy for oral cavity cancer: A retrospective cohort study(2022) Topkan, Erkan; Somay, Efsun; Yilmaz, Busra; Kucuk, Ahmet; 0000-0003-0633-5648; 36041356Item Comment on: Quality of Life After Segmental Mandibulectomy and Free Flap for Mandibular Osteonecrosis: Systematic Review(2023) Topkan, Erkan; Somay, Efsun; 0000-0001-8251-6913; 37459741; AAG-2213-2021Item Comment On: Radiotherapy And Long-Term Sequelae In Pediatric Patients With Parameningeal Rhabdomyosarcoma: Results Of Two Cooperative Weichteilsarkom Studiengruppe (Cws) Trials And One Registry(PEDIATRIC BLOOD & CANCER, 2024-01-31) Somay, Efsun; Topkan, Erkan; Selek, UgurItem Comment on: Required Time for Pre-Oncological Dental Management-A Rapid Review of the Literature(2022) Topkan, Erkan; Somay, Efsun; Yilmaz, Busra; Kucuk, Ahmet; 0000-0001-8120-7123; 0000-0003-0633-5648; 36183502; AAG-2213-2021; AAR-6904-2020Item Comment On: Risk Prediction Of Complicated Course In Patients Undergoing Major Head And Neck Surgery With Free Fl Ap Reconstruction(BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2024-12) Topkan, Erkan; Somay, Efsun; Ozturk, Duriye; Senyurek, SukranItem Commentary On "Effect Analysis Of 847 Nasopharyngeal Carcinoma Cases Treated With Intensity Modulated Radiation: Experience And Suggestions"(ORAL ONCOLOGY, 2024-12) Topkan, Erkan; Somay, Efsun; Ozturk, Duriye; Selek, UgurItem Comparison of Temporomandibular Joint Disorders Between Patients Treated with Hemodialysis versus Peritoneal Dialysis(2022) Tekkarismaz, Nihan; Somay, Efsun; 0000-0001-8251-6913; AAP-9684-2021Objective: The primary aim of this study was to investigate the difference, if any, in the frequency of temporomandibular joint disorders between patients with end-stage kidney disease (ESKD) and healthy individuals. Our secondary aim was to compare the frequency of temporomandibular joint disorders between patients with end-stage kidney disease treated with hemodialysis versus peritoneal dialysis. Methods: All participants completed a questionnaire and underwent a dental evaluation to confirm temporomandibular joint disorder. Results: The frequencies of temporomandibular joint disorders were 13% and 8.9% in the patient and control groups (P =.35), respectively, and 13.4% and 12% in the hemodialysis and peritoneal dialysis groups, respectively (P = 0.85). Conclusions: We observed no difference in temporomandibular joint disorder frequency between patients with end-stage kidney disease who received hemodialysis and peritoneal dialysis as kidney replacement therapy and between patients with ESKD and healthy individuals. Further large-scale studies are warranted to gain a deeper understanding of this topic.Item Confirming the diagnosis of temporomandibular joint disorder by magnetic resonance imaging(2020) Yilmaz, Busra; Somay, EfsunPurpose: The aim of this study was to define the temporomandibular joint complaints of patients with different genders and educational levels and to investigate the accuracy of these complaints with the diagnosis of temporomandibular joint disorder (TJD) with magnetic resonance imaging (MRII). Material and Methods: Temporomandibular joint MRI and clinical examination findings and panoramic radiographs of 99 patients over 18 years of age who applied to the dental clinic between 2011-2018 with the complaint of jaw pain and limited mouth opening are evaluated. The cases which TJD was determined as a result of MRI, are accepted as MRI (+). The ones with the complaints of TJD, but the joint was within normal limits in the MRI, MRI is recorded as (-). Results: There is significant correlation between MRI results and gender but no correlation between MRI results and tooth loss. It is found education level did not have significant effect on the described joint complaints and MRI (+) findings. Conclusion: Women describe temporomandibular joint problems better than men. Even if the level of education is high, patients may not be able to convey their complaints correctly to the physician. Clinical findings should be supported by MRI results in order to diagnose this disease.Item Hemoglobin-to-platelet ratio in predicting the incidence of trismus after concurrent chemoradiotherapy(2023) Somay, Efsun; Yilmaz, Busra; Topkan, Erkan; Kucuk, Ahmet; Haksoyler, Veysel; Pehlivan, Berrin; Selek, Ugur; Araz, Kenan; 0000-0003-0633-5648; 0000-0001-8120-7123; 36038508; AAG-2213-2021Objective The significance of pre-hemoglobin-to-platelet ratio (HPR) in predicting the occurrence of radiation-induced trismus (RIT) in locally advanced nasopharyngeal carcinoma patients (LA-NPC) who received concurrent chemoradiotherapy (C-CRT). Methods The records of LA-NPC patients with oral examination before and after C-CRT were analyzed. Maximum mouth openings (MMO) were measured before and after C-CRT to confirm RIT status, with an MMO of <= 35 mm defined as RIT. HPR values were calculated on the first day of C-CRT. The relationship between the HPR values and RIT status was discovered using the receiver operating characteristic curve analysis. Results A total of 43 patients RIT cases among 198 individuals were diagnosed. The optimal HPR cutoff that stratified the patients into two groups was 0.54. RIT incidence was found to be significantly higher in the HPR <= 0.54 group than its HPR >0.54 counterpart(p < 0.001). Univariately T3-4 stage, mean masticator apparatus dose>57.2Gy, and pre-C-CRT MMO <= 40.7 mm were found as the other significant correlates of increased RIT rates(p < 0.05). All four variables seemed to be independently connected to greater RIT incidence in multivariate analysis (p < 0.05, for each). Conclusion The risk of post-C-CRT RIT may be significantly increased when pre-treatment HPR levels are low.Item High pretreatment systemic immune-inflammation index values are associated with diminished short-term success after temporomandibular joint arthrocentesis procedure(2021) Somay, Efsun; Yilmaz, Busra; 0000-0003-0633-5648; 0000-0001-8251-6913; 34654426Background The systemic immune-inflammation index (SII) has been demonstrated to be a valid biomarker of a patient's immunological and inflammatory state, with the ability to accurately predict outcomes in a variety of disease conditions. In the absence of comparable studies, we intended to examine the relevance of pretreatment SII in predicting the success rates of temporomandibular joint arthrocentesis (TMJA) at 1-week, 1-month, and 6-month periods, defined as maximum mouth opening (MMO) > 35 mm and VAS <= 3. Methods A sum of 136 patients with disc displacement without reduction (DDwo-red) who underwent TMJA was included. For each patient, pre-TMJA SII was calculated as; SII = Platelets x neutrophils/lymphocytes. Additionally, baseline MMO and VAS measurements were recorded for each patient. The success criteria of TMJA included MMO > 35 mm and VAS <= 3. The optimal pre-TMJA SII cutoff that predicts TMJA success was determined using receiver operating characteristic (ROC) curve analysis. The primary endpoint was the link between the pre-treatment SII and TMJA success (simultaneous achievement of MMO > 35 mm and VAS <= 3). Results The median pre-TMJA jaw locking duration, maximum mouth opening (MMO), and visual analog score (VAS) were 7 days, 24 mm, and 8, respectively. The overall TMJA success rates were determined as 80.1%, 91.9%, and 69.1% at 1-week, 1-month, and 6-months, respectively. The results of ROC curve analysis exhibited the optimal SII cutoff at 526 (AUC: 67.4%; sensitivity: 66.7%; specificity: 64.2%) that grouped the patients into two subgroups: Group 1: SII <= 526 (N = 81) and SII > 526 (N = 55), respectively. Spearman correlation analysis revealed a strong inverse relationship between the pretreatment SII values and the success of TMJA 1-week (r(s): - 0.83; P = 0.008) and 1-month, (r(s): - 0.89; P = 0.03). Comparative analyses displayed that TMJA success rates at 1-week (87.7% vs. 69.1%; P = 0.008) and 1-month (96.2% vs. 80%; P = 0.03) were significantly higher in the SII <= 526 than SII > 526 group, respectively, while the 6-month results favored the SII <= 526 group with a trend approaching significance (P = 0.084). Conclusion The current study's findings suggested the SII as a unique independent prognostic biomarker that accurately predicts treatment outcomes for up to 6 months. Trial registration The results of this research were retrospectively registered.Item In Reference To Primary Site Surgical Resection In Cm1 Oral Cavity Squamous Cell Carcinoma(LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY, 2024-12) Topkan, Erkan; Somay, Efsun; Selek, UgurItem In Regard to Cong Et Al.(ORAL DISEASES, 2024) Topkan, Erkan; Somay, Efsun; Selek, UgurItem In regard to recent published study of Lombardi et al. titled 'Pentoxifylline and tocopherol for prevention of osteoradionecrosis in patients who underwent oral surgery: A clinical audit'. (Spec Care Dentist. 2022;10.1111/scd.12759. )(2023) Topkan, Erkan; Somay, Efsun; Yilmaz, Busra; 0000-0003-0633-5648; 36042005Item In regard to recent published study of Massaccesi et al. titled 'A predictive nomogram for trismus after radiotherapy for head and neck cancer'. (Radiother Oncol. 2022 Jun 2: S0167-8140(22)04137-8. doi: 10.1016/j.radonc.2022.05.031)(2022) Topkan, Erkan; Somay, Efsun; Yilmaz, Busra; 0000-0003-0633-5648Item In Reply to Bertl et al.(2023) Somay, Efsun; Topkan, Erkan; Selek, Ugur; 0000-0001-8087-3140; 0000-0001-8120-7123; 0000-0001-8251-6913; O-5474-2014; AAG-2213-2021Item In reply to Cheng et al. (DOI: 10.1186/s13550-023-00965-8)(2023) Somay, Efsun; Topkan, Erkan; Pehlivan, Berrin; Selek, Ugur; 0000-0001-8251-6913; 0000-0001-8120-7123; 37589948; AAG-2213-2021
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