Browsing by Author "Sahin, H."

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Evaluation of Hs-CRP and Visseral Adiposity Index in Patients with Policystic Ovary Syndrome by Clinical and Laboratory Findings
(2016) Un, B.; Dolapcioglu, K. S.; Okyay, A. Guler; Sahin, H.; Beyazit, A.; 27479317
Aim: In this study, we aimed to evaluate two cardiovascular risk markers, hs-CRP and visseral adiposity index, in patients with policystic ovary syndrome in association with clinical and laboratory findings. Material and method: Study group included 75 patients who were diagnosed as PCOS according to the criteria of AE-PCOS 2006 and control group included 75 non-PCOS patients who were subsequently admitted to outpatient clinic for smear control, with urinary or vaginal symptoms. Physical and sonographic examinations were made to all subjects. Mean arterial pressure, waist/hip ratio and body mass index were calculated. Fasting blood glucose and insulin, HbA1c, lipids, high sensitivity C-reactive protein (hs-CRP), estradiol, follicle stimulating hormon, luteinising hormone, timid stimulating hormone, prolaktin, total testosteron and sex hormone binding globulin were tested in venous blood samples collected from cases following overnight fast in follicular phase of spontaneous or induced menstruation. Visceral adiposity index was also calculated. Findings: No statistically significant difference was found between PCOS group and control group concerning hs-CRP and VAI (p > 0.05). When patients in PCOS group were further grouped as obese and non-obese, hs-CRP and VAI values in obese group were significantly higher than those in non-obese. group (p < 0.001). However, when control group were further grouped as obese and non-obese, there was no significant difference in terms of hs-CRP between groups (p > 0.05), VAI values were significantly higher in obese control group (p < 0.05). Conclusion: According to the results of our study, hs-CRP stands for a better and more specific marker than VAI to determine metabolic components and predictive risks for cardiovascular diseases in patients with PCOS. Further studies with larger populations are needed in order to determine cardiovascular risks particularly in young PCOS patients. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
Incidence and Outcome of Occult Uterine Sarcoma: A Multi-Centre, Retrospective Study of 18604 Operations Performed for Presumed Uterine Leiomyoma
(2019) Yorganci, A; Meydanli, M. M.; Kadioglu, N.; Sahin, H.; Kayikcioglu, F.; Taskin, S.; Atasoy, L.; Akgul, M. A.; Kinay, T.; Tapisiz, O. L.; Haberal, N.; Evliyaoglu, O.; Tekin, O. Moraloglu; Ortac, F.; Ayhan, A.; https://orcid.org/0000-0001-9852-9911; AEY-5060-2022; AAK-4587-2021; AAJ-5802-2021
Role of Initial Surgery in Malignant Ovarian Germ Cell Tumors
(2017) Kocaman, E.; Coban, G.; Sahin, H.; Akilli, H.; Celik, H.; Kuscu, E.; Ayhan, A.; 0000-0002-3285-5519; 0000-0002-0992-6980; AAI-9974-2021; AAL-1923-2021; AAI-8792-2021; AAJ-5802-2021
Role of Initial Surgery in Malignant Ovarian Germ Cell Tumors
(2016) Kocaman, E.; Coban, G.; Sahin, H.; Akilli, H.; Celik, H.; Kuscu, E.; Ayhan, A.; 0000-0002-3285-5519; 0000-0002-0992-6980; AAI-9974-2021; AAJ-5802-2021; AAI-8792-2021; AAL-1923-2021
Serum ischemia modified albumin and endometrial cancer: a prospective case-control study
(2019) Sahin, H.; Ayhan, S.; Sari, M.E.; Tohma, V.A.; Yaman, S.; Yalcin, I.; Candar, T.; Gungor, T.
Objective: To investigate the importance of ischemia modified albumin (IMA) in the diagnosis and evaluation of endometrial carcinoma. Material and Methods: Serum IMA levels of patients with and without endometrial cancer were measured by the calorimetric assay technique and their absorbance units were compared. Results: A total of 128 women were included in the study; 64 of these women were endometrial cancer patients and 64 of them were in the control group. The median age for these groups were 58.5 and 56 years, respectively. There was no significant difference in terms of age, body mass index, and serum albumin levels between the groups (p > 0.05). In the endometrial cancer group, the median serum IMA level was 0.489 (0.401-0.611), while in the control group the median serum IMA level was 0.490 (0.407-0.589). There was no significant difference between these two groups (p = 0.467). In the type 1 endometrial cancer group, the median serum IMA level was 0.452 (0.401-0.590), while in the type 2 endometrial cancer group the median serum IMA level was 0.559 (0.462-0.611) A significant difference was found between types 1 and 2 endometrial cancers (p < 0.001). Conclusions: The IMA level does not appear to be an additional predictive marker of preoperative diagnosis and evaluation of endometrioid type endometrial cancer when compared to the healthy control group; on the other hand, IMA may be a marker for the detection of type 2 endometrium cancers when compared with type 1 endometrium tumors. However, further randomized controlled trials are required to make a comparison between type1 and type2 endometrial cancers.