Browsing by Author "Keskin, Gul Sema"

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    Relationship between plasma YKL-40 levels and endothelial dysfunction in chronic kidney disease
    (2019) Keskin, Gul Sema; Helvaci, Ozant; Yayla, Cagri; Pasaoglu, Ozge T.; Keskin, Caglar; Arinsoy, Turgay; Deric, Ulver B.; 30763987
    Background/aim: We aimed to evaluate the relationship between YKL-40 and endothelial dysfunction in chronic kidney disease. Materials and methods: Twenty-nine hemodialysis patients, 101 patients with nondialytic (stage 2, 3, 4, and 5 ND) chronic kidney disease (CKD), and 38 healthy individuals as a control group were included. YKL-40 levels were measured by ELISA. Endothelial dysfunction was indirectly measured by flow-mediated dilatation percentage (FMD) in the brachial artery. Results: YKL-40 levels were higher in CKD patients than controls and highest in HD patients (P = 0.001). FMD values were lower in nondialytic CKD patients and lowest in HD patients (P = 0.001). YKL-40 negatively correlated with eGFR and FMD values (r = -0.674 and r = -0.471, respectively). Conclusion: This study shows that YKL-40 increases with CKD stage and is negatively correlated with FMD measurements.
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    Treatment of Lymph Node-Negative, Early-Stage HER2-Positive Breast Cancer
    (2016) Oguz, Arzu; Keskin, Gul Sema; Colak, Dilsen; Altundag, Ozden; Akcali, Zafer; https://orcid.org/0000-0001-6512-6534; https://orcid.org/0000-0003-0197-6622; https://orcid.org/0000-0003-2473-4431; 26644534; W-8004-2019; GRY-5456-2022; GRY-5456-2022; W-9219-2019; U-7339-2017