Browsing by Author "Dolgun, Anil"

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    A Comparision of Axillary with Infrared Tympanic and Non-Contact Infrared Thermometry
    (2016) Coban, Bayram; Dolgun, Anil; 0000-0002-2693-0666; D-4235-2013
    Objective: Ideally, the temperature measurement should be safe, easy, noninvasive, cost effective, time efficient and technique independent and should precisely reflect core body temperature and should not be influenced by the environmental temperature. In our study, we compared the axillary digital with infrared tympanic and forehead non-contact infrared measurement. Material and Methods: Axillary digital, tympanic infrared and non-contact forehead measurements were taken simultaneously with devices used in hospital routinely. Results: Temperature was measured for 276 patients between 0 and 14 years old. Infrared tympanic measurements were significantly higher than axillary (p<0.001) and non-contact infrared measurements (p<0.001). There was no difference between axillary and forehead measurements (p=0.999). Feverish patients who measured by axillary method was not detected in 11.6% of tympanic and 41.9% of non-contact forehead measurements. Conclusion: Tympanic infrared measurements are higher than axillary digital and non-contact infrared measurements. Temperature measurement must be reassured with other techniques in case of any doubt.
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    SEROUS VERSUS HIGH-GRADE ENDOMETRIOID ENDOMETRIAL CARCINOMA: IMMUNOHISTOCHEMISTRY OF RFP IS NOT USEFUL FOR DIFFERENTIATION
    (2016) Ussakli, Cigdem; Usubutun, Alp; Dicner, Nazmiye; Dolgun, Anil; Bulbul, Dilek; Isikdogan, Zuhal; Haberal, Nihan; Ozen, Ozlem; Tezel, Gaye Guler; 0000-0001-9852-9911; 28155970; AAK-4587-2021
    We evaluated the immunohistochemical expression of ret finger protein (RFP) along with conventional immunohistochemical markers in endometrioid and serous carcinomas of the endometrium. A total of 124 endometrial carcinoma cases (24 grade 1 endometrioid, 60 grade 3 endometrioid, 40 serous) were retrieved from pathology archives. Tissue microarrays were constructed. The expression of RFP, WT1, ER., PR, p53 and p16 was examined immunohistochemically. Sensitivity, specificity, area under the receiver operating characteristic (ROC) curve, kappa statistic for interobserver reproducibility, Kruskal-Wallis test, Mann-Whitney U test and Fisher's exact tests were performed for statistical analyses. The mean RFP score was 1.54 in grade 1 endometrioid, 4.31 in grade 3 endometrioid, and 6.31 in serous carcinomas (p < 0.001). Overall, RFP scores were higher both in serous and grade 3 endometrioid carcinoma (p > 0.05), and significantly lower in grade 1 endometrioid carcinoma (p < 0.05). p16 and p53 staining patterns were able to differentiate between high-grade endometrioid and serous carcinoma (p < 0.001). ER, PR and WT-1 did not reach statistical significance for subtyping. The kappa values of the general agreement between the observers were 0.737 and 0.727 for endometrioid and serous carcinomas respectively (p < 0.001). Diffuse p53 and p16 staining provides the most sensitive and specific immunomarkers for differentiating high-grade endometrioid and serous carcinomas.