Browsing by Author "Cetin, Mehtap Bilgin"

Now showing 1 - 9 of 9

About Assessment of Carotid Artery Calcifications on Radiographs Response
(2022) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Yilmaz, Mediha Nur Nisanci; Secgin, Cansu Koseoglu; 35131087; AAC-5931-2020
COMPARISON OF TWO MORPHOMETRIC LINEAR METHODS FOR ALVEOLAR BONE LOSS MEASUREMENT IN EXPERIMENTAL PERIODONTITIS
(2019) Cetin, Mehtap Bilgin; Sezgin, Yasemin
Aim: The aim of this study was to compare direct (performed by a dental loop, periodontal probe and digital caliper over the alveolar bone) and indirect (performed by means of a special software program on digital photographs) linear morphometric measurements to assess the alveolar bone loss. Material and methods: Thirty right mandible of Sprague Dawley rats were obtained from a previous study that induced periodontitis with ligature model. In direct measurement group, the distance between cemento -enamel junction and alveolar bone crest was evaluated by digital caliper and periodontal probe using a dental loop, whereas in indirect group by an image analysis program on digital photographs. The difference between the groups was determined by Mann-Whitney U test. Results and discussions: Mean alveolar bone loss was 1.08 +/- 0.22 mm in direct measurement group and 1.19 +/- 0.33 mm in indirect measurement group. The difference between direct and indirect groups was not statistically significant (p>0.05). Conclusions: Based on the present result, it can be concluded that, the use of direct morphometric analysis may be an alternative to indirect morphometric evaluations for measuring alveolar bone loss in rats after the induction of experimental periodontitis.
Comparison of Two Morphometric Linear Methods to Measure the Alveolar Bone Loss Induced by Experimental Periodontal Disease in Rats
(2020) Cetin, Mehtap Bilgin; Sezgin, Yasemin
Objective: The aim of this study was to compare the direct and indirect linear morphometric measurements for the evaluation of alveolar bone loss after experimentally induced periodontitis in rats. Materials and Methods: Right mandibles of 30 Sprague Dawley rats were collected from a previous study which induced periodontitis using ligature model. In direct measurement group, the distance between cementoenamel junction and alveolar bone crest was evaluated by digital caliper and periodontal probe with a dental loop, whereas indirect group measurement was performed by an image analysis program on digital photographs. Results: The difference between groups was determined using Mann-Whitney U test. Average alveolar bone loss was 1.08 +/- 0.22 mm in direct measurement group and 1.19 +/- 0.33 mm inindirect measurement group. The variation between direct and in direct groups was not statistically significant (p>0.05). Conclusion: Based on the present result, it can be concluded that, direct morphometric analysis might be an essential alternative to indirect morphometric evaluations to measure alveolar bone loss after experimentally induced periodontitis in rats.
Evaluating the Effects of a Topical Preparation with Dexpanthenol, Silbiol, Undecylenic Acid, and Lidocaine on Palatal Mucosa Wound Healing in a Rat Model
(2019) Sezgin, Yasemin; Cetin, Mehtap Bilgin; Bulut, Sule; Alptekin, Nilgun Ozlem; Borcek, Pelin; 0000-0003-4104-6462; 30322831; G-1816-2014; AAC-5448-2020; AAC-5931-2020
Background: Postoperative complications occur after periodontal plastic surgeries, but an ideal treatment to overcome them has not been found yet. Aims: To evaluate the effects of topically applied Oral-norm gel on the healing of excisional wounds. Study Design: Animal experiment. Methods: Excisional wounds with a diameter of 3 mm were made in the center of the palatal mucosa of 63 Sprague Dawley rats. Seven animals were sacrificed at time 0. The remaining rats were divided into two groups: a test group in which the topical Oral-norm gel was applied three times a day and a control group in which nothing was applied. Seven animals in each group were sacrificed at 3, 7, 14, and 21 days. Mean wound surface area was measured photographically, while wound healing and width were evaluated microscopically. Results: The mean wound surface area decreased significantly after 3 days in both groups (p<0.001). Between days 3 and 7, the mean wound surface area decreased from 6.62 (2.85) to 0.83 (1.62) mm 2 in the control group and 5.07 (0.88) to 1.42 (1.67) mm 2 in the test group. The wound width decreased significantly on day 7 in both groups (p<0.001), with no further changes by day 14. Both groups had a significant increase in inflammation and vascularization on day 3 (p<0.001), with a reduction thereafter. No significant differences in macroscopic and microscopic measurements were observed between the groups at any time point (p>0.05). Conclusion: The Oral-norm gel has no positive healing effects in the palatal mucosa of rats.
Evaluating the Impacts of Some Etiologically Relevant Factors on Excessive Gingival Display
(2021) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Akinci, Seray; Bakirarar, Batuhan; 33819318
The literature offers limited and even conflicting information on the etiology of gummy smile. Therefore, this study aimed to evaluate smile line, hypermobile upper lip (HUL), altered passive eruption (APE), and short upper lip (SUL) distribution in a group of patients seeking dental treatment and to examine their effects on gummy smile. A total of 501 individuals (265 men, 236 women) were included in the study. The patients were grouped by gingival display, and presence of HUL, APE, and SUL were evaluated. Multivariate Logistic Regression analyses were performed to investigate the impact of possible risk factors on gummy smile. Of the individuals, 173 (34.5%) had a low smile line, 127 (25.3%) had an average smile line, 146 (29.1%) had a high smile line, and 55 (10.9%) were gummy smile patients. Individuals with gummy smile were younger than the individuals with low smile line (P < .001). As for the possible risk factors for gummy smile, age (odds ratio [OR]: 0.936; 95% CI: 0.901 to 0.972; P = .001), HUL (OR: 18.85; 95% CI: 7.82 to 45.44; P < .001), and APE (OR: 8.819; 95% CI: 3.894 to 19.973; P < .001) were found to be significant together. Gender and SUL/upper lip length were not found to have any impact on gummy smile. HUL is the primary factor that increases the probability of having gummy smile, followed by APE as the secondary factor. It seems reasonable to focus on correction of the HUL for treatment in most gummy smile patients.
Evaluating Well-being Among Dental Students Using the Warwick-Edinburgh Mental Well-being Scale and the Relationship Between Mental Well-being and Socio-demographic Findings
(2021) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Akinci, Seray; Alptekin, Nilgun Ozlem; 0000-0003-4104-6462; G-1816-2014
Objective: The present study aimed to measure mental well-being among dental students using the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) and to investigate factors affecting well-being. Materials and Methods: Baskent University Faculty of Dentistry students were invited to participate in the study in 2019. The participants were asked to complete the WEMWBS and a questionnaire describing their demographic details, social background and lifestyle habits. Results: A total of 268 dental students (68% females) participated in the survey, with a response rate of 85%. The overall WEMWBS score of the study population was 48.18 +/- 9.6. Statistically significant differences in WEMWBS scores were detected between first- and fourth-year (p<0.001) students and between fourth- and fifth-year students (p<0.001). Male students (p<0.001) whose first choice was to attend the school of dentistry (p=0.024) and who pursued hobbies (p=0.001) or regular sports activities (p=0.001) had significantly higher WEMWBS scores than those who did not. Dental students' smoking status (p=0.630), living accommodation (p=0.71) or parents' education level did not affect WEMWBS scores significantly. Conclusion: The mental well-being of dental students was influenced by their year of study, gender, first choice of school and pursuit of hobbies or regular sports activities. Factors that may affect the mental well-being of students should be carefully considered, and strategies should be implemented to monitor and promote well-being during the students' academic career.
Evaluation of the Effect of Periodontitis on Quality of Life Using Oral-Dental Health-Related Quality of Life-United Kingdom Scale
(2021) Kutsal, Derya; Cetin, Mehtap Bilgin; Durukan, Elif; Bulut, Sule; 0000-0002-8579-5564; 33797852; AAJ-8621-2021
Objective The aim of this study was to investigate the impact of periodontitis on oral health-related quality of life (OHQoL) using Oral-Dental Health-Related Quality of Life-United Kingdom (OHRQoL-UK) scale and evaluate the contributing factors. Methods 50 patients with untreated periodontitis and 50 individuals without periodontitis were enrolled in the study. All subjects received detailed periodontal examination. Plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) measurements were examined. OHRQoL was assessed by the Oral Health Quality of Life-United Kingdom (OHRQoL-UK) scale. Symptoms of periodontitis were monitored by visual analogue scale (VAS). Socio-demographic characteristics, medical history, smoking status, hygiene habits of the participants were recorded. This study is registered at ClinicalTrials.gov as NCT04240014. Results Total OHRQoL-UK scores were 38.24 +/- 6.47 in periodontitis patients and 55.88 +/- 9.38 in non-periodontitis individuals (p < 0.001). The scores of all 4 parameters were significantly lower in patients with periodontitis compared to healthy individuals (p <0.001). Higher PI, GI, PD and CAL values were associated with extensive negative impacts of periodontitis on OHRQoL (p < 0.001). According to the results of linear regression analysis, only periodontitis was found to associate with OHRQoL. Periodontal disease reduces the total quality of life score by 15.087 (ss= -15.087; 95% CI = [(-18.934)-(-11.240)]. Conclusions Individuals with periodontitis has diminished OHRQoL compared to healthy individuals.
The relationship between body mass index and stage/grade of periodontitis: a retrospective study
(2021) Cetin, Mehtap Bilgin; Sezgin, Yasemin; Onder, Canan; Bakirarar, Batuhan; 34709456
Objectives Possible impact of obesity on stage and grade of periodontitis has never been investigated before. This study aimed to examine the association between body mass index (BMI) and stage/grade of periodontitis per the current classification of periodontal diseases. Material and methods A total of 142 patients (82 males/60 females) were included in this study. "2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions" was taken as basis to characterize the stage/grade of periodontitis. Age, gender, smoking status, and frequency of tooth brushing, and medical data of the patients including hypertension, hyperlipidemia, BMI, and diabetes mellitus were obtained from the patient's hospital records. Obesity was assessed by BMI using the "World Health Organization" criteria. For estimating the association between BMI and periodontitis, logistic regression analysis was utilized. Results BMI was statistically associated with clinical attachment loss (CAL), probing pocket depth (PPD), Plaque index (PI), stage and grade of periodontitis, and number of remaining teeth (p < 0.001, p < 0.05, p < 0.05, p < 0.05, p < 0.001, respectively). According to the multiple regression analysis results, those with BMI 25-29.9 were found to be at risk of being stage III-IV 3.977 times (95% CI: 1.831-8.640, p < 0.001) higher than those with BMI < 25, and similarly, those with BMI >= 30 were found to be at risk of being stage III-IV 4.062 times (95% CI: 1.315-12.549, p = 0.015) higher than those with BMI < 25. No relationship was found between obesity and grade of periodontitis according to multivariate analysis. Conclusions BMI increases the likelihood of stage III and stage IV periodontitis; however, it does not have an impact on the grade of periodontitis.
Relationship of periodontitis and edentulism to angiographically diagnosed coronary artery disease: A cross-sectional study
(2020) Cetin, Mehtap Bilgin; Onder, Canan; Orhan, Kaan; Kumbasar, Deniz; Serdar, Muhittin Abdulkadir; Unsal, Elif; 32648271
Objective The objective of the study is to examine the connection between oral status and the extent of coronary artery disease (CAD), which is diagnosed by angiography. Background Periodontitis and tooth loss have been linked to atherosclerosis and CAD in previous studies. However, no distinct connection was revealed due to the diversity of the results and the variety of diagnostic methods. To provide a more consistent data pool and stronger evidence, there is a need for studies with standard measurements and diagnostic criteria. Methods 309 patients, who consulted to Ankara University, Faculty of Medicine, Department of Cardiology and had coronary angiography, were enrolled to this study. Individuals were grouped based on their coronary angiography results, as CAD (+) (n = 233) and CAD (-) (n = 76). Studied parameters included cardiovascular risk factors, plaque index (PI), remaining teeth count, bleeding on probing (BOP), and probing pocket depth (PPD). Periapical radiographs were taken from teeth with >= 4 mm PPD. Oral status was categorized as periodontally healthy subjects/patients with gingivitis (Group 1), patients with periodontitis (Group 2), and edentulous subjects (Group 3). Results PI (P < 0.001), PPD (P = 0.001), BOP (P = 0.004), the number of patients with less than 10 teeth (P = 0.014), and edentulism (P = 0.009) were significantly higher in CAD (+) patients, who were mostly older (P < 0.001) and male (P < 0.001). Multivariate logistic regression analysis revealed that Group 2 (odds ratio = 2.48, 95% confidence interval = 1.24-4.95,P = 0.010) and Group 3 (odds ratio = 2.01, 95% confidence interval = 1.14-5.17,P = 0.040) were highly associated with CAD. Two and three stenosed vessels were significantly higher in Groups 2 and 3 compared to Group 1 (P = 0.003). Conclusions It was found that both edentulism and periodontitis were related to CAD.