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  1. Home
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Browsing by Author "Boyacioglu, Sedat"

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    Auxiliary Partial Orthotopic Living Liver Transplant for Wilson Disease
    (2017) Haberal, Mehmet; Akdur, Aydincan; Moray, Gokhan; Boyacioglu, Sedat; Torgay, Adnan; Arslan, Gulnaz; Ozdemir, Binnaz Handan; 0000-0002-6829-3300; 0000-0002-3462-7632; 0000-0003-2498-7287; 0000-0002-8726-3369; 0000-0002-7528-3557; 0000-0002-9370-1126; 28260463; AAJ-5221-2021; AAJ-8097-2021; AAE-1041-2021; AAA-3068-2021; X-8540-2019; AAE-7637-2021
    Wilson disease is a genetic disease involving copper metabolism disturbances that result in copper accumulations, especially in the liver and brain. Wilson disease can be treated with pharmacologic agents, such as chelators that induce urinary excretion of copper or zinc salts that inhibit copper absorption in the digestive tract. Liver transplant is the only treatment option for Wilson disease when liver failure has occurred. In some patients, that is, in those with Child-Pugh A score, neurologic disease can be seen without hepatic failure. Our recommendation is for these patients to have auxiliary partial orthotopic liver transplant. Here, we present a 36-year-old male patient with neurologic disease associated with Wilson disease who had successful related living-donor auxiliary partial orthotopic liver transplant using a left lobe. The patient, as a result of neurologic symptoms that included tremor walking and speaking problems and low serum ceruloplasmin level of 7 mg/dL, was diagnosed with Wilson disease, and a liver biopsy was performed. Chronic necroinflammatory disease activity was 4/18, and the patient received chelation treatment. His hepatic functions were normal. The donor was the patient's 57-year-old father whose liver function tests were also normal. The graft-to-recipient weight ratio was 1% using a left lobe graft. After transplant, serum ceruloplasmin levels on day 15 and month 1 were 14 and 19 mg/dL. At month 1, liver function tests were normal. Doppler ultrasonography showed normal vascular flow of the native liver and the graft. The patient's neurologic symptoms were progressively reduced. Progressive neurologic deterioration with no hepatic insufficiency is considered a suitable indication for auxiliary partial orthotopic liver transplant; this procedure is suggested before the neurologic and liver failure symptoms of Wilson disease occur.
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    Clinical Course of Inflammatory Bowel Disease and Primary Sclerosing Cholangitis after Liver Transplantation
    (2018) Dagli, Ulku; Etik, Digdem Ozer; Akdur, Aydincan; Selcuk, Haldun; Hilmioglu, Fatih; Boyacioglu, Sedat; Moray, Gokhan; Haberal, Mehmet; 0000-0003-0664-0976; 0000-0002-4724-0728; 0000-0002-8726-3369; 0000-0002-8445-6413; 0000-0002-6440-5686; 0000-0002-9370-1126; 0000-0003-2498-7287; 0000-0002-3462-7632; S-4068-2018; AAJ-4707-2021; AAA-3068-2021; AAJ-6976-2021; AAJ-4437-2021; AAE-7637-2021; AAE-1041-2021; AAJ-8097-2021
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    The effect of bleomycin embolization on symptomatic improvement and hemangioma size among patients with giant liver hemangiomas
    (2018) Kirnap, Mahir; Boyvat, Fatih; Boyacioglu, Sedat; Hilmioglu, Fatih; Moray, Gokhan; Haberal, Mehmet; 0000-0003-2498-7287; AAH-9198-2019
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    Efficacy And Safety Of Tenofovir Alafenamide In Hepatitis B Virus-Infected Patients With Chronic Hemodialysis And Renal Transplantation: A Preliminary Result
    (2021) Etik, Digdem Ozer; Boyacioglu, Sedat
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    Efficacy and Tolerability of Direct-Acting Antiviral Agents for Hepatitis C Virus Infection in Kidney Transplant Recipients
    (2018) Suna, Nuretdin; Etik, Digdem Ozer; Ocal, Serkan; Selcuk, Haldun; Dagli, Ulku; Hilmioglu, Fatih; Boyacioglu, Sedat; Haberal, Mehmet; https://orcid.org/0000-0001-6234-7788; https://orcid.org/0000-0003-3719-9482; https://orcid.org/0000-0002-8445-6413; https://orcid.org/0000-0002-6440-5686; https://orcid.org/0000-0002-9370-1126; https://orcid.org/0000-0002-3462-7632; AAI-8822-2021; ABH-4817-2020; AAJ-6976-2021; AAJ-4437-2021; AAE-7637-2021; AAJ-8097-2021
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    Extraordinary biliary variant
    (2017) Suna, Nuretdin; Etik, Digdem Ozer; Ocal, Serkan; Selcuk, Haldun; Hilmioglu, Fatih; Boyacioglu, Sedat; 0000-0003-3719-9482; 0000-0002-9370-1126; 0000-0002-6440-5686; 0000-0002-4724-0728; 0000-0002-8445-6413; 0000-0001-6234-7788; 28336501; ABH-4817-2020; AAE-7637-2021; AAJ-4437-2021; AAJ-4707-2021; AAJ-6976-2021; AAI-8822-2021
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    Liver Transplantation and Auxiliary Partial Orthotopic Transplantation Outcomes in Wilson's Disease: Results of a Single Center
    (2018) Soy, Ebru H. Ayvazoglu; Akdur, Aydincan; Moray, Gokhan; Boyacioglu, Sedat; Torgay, Adnan; Arslan, Gulnaz; Ozdemir, Handan; Haberal, Mehmet; https://orcid.org/0000-0002-0993-9917; https://orcid.org/0000-0002-8726-3369; https://orcid.org/0000-0003-2498-7287; https://orcid.org/0000-0002-9370-1126; https://orcid.org/0000-0002-6829-3300; https://orcid.org/0000-0002-7528-3557; https://orcid.org/0000-0002-3462-7632; AAC-5566-2019; AAA-3068-2021; AAE-1041-2021; AAE-7637-2021; AAJ-5221-2021; X-8540-2019; AAJ-8097-2021
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    Percutaneous Transhepatic Tips for Budd-Chiari Syndrome: Direct Simultaneous Puncture of Portal Vein and Inferior Vena Cava
    (2018) Boyvat, Fatih; Harman, Ali; Soy, Ebru H. Ayvazoglu; Aytekin, Cuneyt; Moray, Gokhan; Boyacioglu, Sedat; Haberal, Mehmet; 0000-0002-7386-7110; 0000-0002-0993-9917; 0000-0003-2498-7287; 0000-0002-9370-1126; 0000-0002-3462-7632; F-4230-2011; K-9824-2013; AAC-5566-2019; AAE-1041-2021; AAE-7637-2021; AAJ-8097-2021
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    Preliminary Results Of The Effectiveness And Safety Of Tenofovir Alefenamide Fumarate Prophylaxis In HBV-Infected Individuals, Who Received Chemo/Immunosuppressive Therapy
    (2022) Gunduz, Feyza; Durak, Serdar; Unsal, Yasemin; Demir, Mehmet; Ellik, Zeynep Melekoglu; Yildirim, Abdullah Emre; Mehdiyev, Shahin; Adanir, Haydar; Demirtas, Coskun Ozer; Ucbilek, Enver; Balaban, Yasemin; Koc, Elif Sitre; Etik, Digdem Ozer; Gokcen, Pinar; Ari, Derya; Gokcan, Hale; Yapali, Suna; Ekmen, Nergis; Arslan, Mehmet; Kayhan, Meral Akdogan; Ozdil, Kamil; Sezgin, Orhan; Boyacioglu, Sedat; Simsek, Halis; Tozun, Nurdan; Dincer, Dinc; Idilman, Ramazan
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    A rare cause of gastric outlet obstruction
    (2017) Suna, Nurettin; Ocal, Serkan; Etik, Digdem Ozer; Selcuk, Haldun; Hilmioglu, Fatih; Boyacioglu, Sedat; 0000-0001-6234-7788; 0000-0003-3719-9482; 0000-0002-8445-6413; 0000-0002-4724-0728; 0000-0002-6440-5686; 0000-0002-9370-1126; 28705787; AAI-8822-2021; ABH-4817-2020; AAJ-6976-2021; AAJ-4707-2021; AAJ-4437-2021; AAE-7637-2021
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    Real Life Efficacy And Tolerability Of Tenofovir Alafenamde Fumarate In Liver Transplant Recipients: A Multicenter Study
    (2022) Gokcan, Hale; Yapali, Suna; Harputluoglu, Murat; Ellik, Zeynep Melekog. Lu; Gokcen, Pinar; Adanir, Haydar; Cosar, Arif Mansur; Durak, Serdar; Ari, Derya; Mehdiyev, Shahin; Koc, Elif Sitre; Guzelbulut, Fatih; Alkim, Huseyin; Ekmen, Nergis; Yildirim, Abdullah Emre; Unsal, Yasemin; Teker, Tufan; Etik, Digdem Ozer; Vatansever, Sezgin; Balaban, Hatice Yasemin; Ozdil, Kamil; Arslan, Mehmet; Kayhan, Meral Akdogan; Gunduz, Feyza; Kiyici, Murat; Boyacioglu, Sedat; Simsek, Halis; Tozun, Nurdan; Dincer, Dinc; Idilman, Ramazan
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    Real Life Efficacy And Tolerability Of Tenofovir Alafenamide Fumarate In Patients With Hepatitis B Virus-Related Cirrhosis And Liver Transplant Recipients. A-Preliminary Result
    (2021) Etik, Digdem Ozer; Boyacioglu, Sedat
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    Relation of Preoperative and Postoperative Echocardiographic Parameters With Rejection and Mortality in Liver Transplant Patients
    (2020) Yilmaz, Kerem Can; Ciftci, Orcun; Akgun, Arzu Neslihan; Muderrisoglu, Haldun; Boyacioglu, Sedat; Haberal, Asuman Nihan; Moray, Gokhan; Haberal, Mehmet; 0000-0001-8926-9142; 0000-0002-9635-6313; 0000-0003-2498-7287; 0000-0002-9370-1126; 0000-0001-9852-9911; 0000-0002-3462-7632; 29790458; W-5233-2018; AAG-8233-2020; AAJ-1331-2021; AAE-1041-2021; AAE-7637-2021; AAK-4587-2021; AAJ-8097-2021
    Objectives: Survival in liver transplant after end-stage liver disease is associated with major cardiac functions. In a significant number of patients with end-stage liver disease, cardiac dysfunctions may be observed, which can include high-output heart failure, cardiac valve disease, and pulmonary venous and arterial hypertension. All of these affect perioperative survival. The aim of our study was to determine whether preoperative and postoperative echocardiographic parameters, specifically right heart-related tricuspid regurgitation, estimated systolic pulmonary arterial pressure, and tricuspid annular plane systolic excursion, are associated with rejection and mortality in liver transplant patients. Materials and Methods: Adult patients (> 18 years old) who underwent liver transplant at our center between January 2011 and March 2017 were included in the study, with 64 patients retrospectively screened. The echocardiographic images that were taken immediately before and immediately after liver transplant were evaluated. The patients were divided into 2 groups according to rejection data and mortality. All parameters were analyzed for both variables. Results: For the 24 patients with liver rejection and 40 patients without liver rejection, there were no statistically significant differences in terms of demographic data, echocardiographic parameters, and laboratory data. However, when patients were evaluated according to survival, there was a statistically significant difference between these 2 groups concerning the echocardiography parameters of systolic pulmonary arterial pressure (P = .005), tricuspid annular plane systolic excursion (P = .001), and postoperative right ventricular width (P = .01). Conclusions: Echocardiography, being a simple and easily accessible technique that is reliable in excluding pulmonary hypertension diagnosis, can be used as a guide in the evaluation of right ventricular function and tricuspid regurgitation, particularly in patients who are not hemodynamically stable before and after liver transplant.
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    Single Center Study on Liver Transplantation Since 1988: Expected Life Expectancy and Affecting Factors
    (2022) Erdal, Rengin; Arslan, Gulnaz; Moray, Gokhan; Boyacioglu, Sedat; Ozcay, Figen; Torgay, Adnan; Haberal, Mehmet; 0000-0002-6829-3300; 0000-0002-3462-7632; 0000-0002-5214-516X; AAJ-5221-2021; AAJ-8097-2021; ABG-5684-2020
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    Successful Treatment with Direct-Acting Antiviral Agents of Hepatitis C in the Setting of End-Stage Renal Disease
    (2018) Etik, Digdem Ozer; Suna, Nuretdin; Ocal, Serkan; Selcuk, Haldun; Dagli, Ulku; Colak, Turan; Hilmioglu, Fatih; Boyacioglu, Sedat; Haberal, Mehmet; 0000-0002-4724-0728; 0000-0001-6234-7788; 0000-0003-3719-9482; 0000-0002-8445-6413; 0000-0003-0664-0976; 0000-0002-8372-7840; 0000-0002-6440-5686; 0000-0002-9370-1126; 0000-0002-3462-7632; AAJ-4707-2021; AAI-8822-2021; ABH-4817-2020; AAJ-6976-2021; S-4068-2018; AAJ-8554-2021; AAJ-4437-2021; AAE-7637-2021; AAJ-8097-2021
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    Uniting the global gastroenterology community to meet the challenge of climate change and non-recyclable waste
    (2021) Leddin, Desmond; Omary, M. Bishr; Veitch, Andrew; Metz, Geoffrey; Amrani, Naima; Aabakken, Lars; Ali, Raja Affendi Raja; Alvares-Da-Silva, Mario Reis; Armstrong, David; Boyacioglu, Sedat; Chen, Ye; Elwakil, Reda; Fock, Kwong-Ming; Hamid, Saeed S.; Makharia, Govind; Macrae, Finlay; Malekzadeh, Reza; Mulder, Chris J.; Piscoya, Alejandro; Perman, Mai Ling; Sadeghi, Anahita; Saenz, Roque; Saurin, Jean-Christophe; Butt, Amna Subhan; Wu, Kaichun; Lee, Yeong Yeh; 34620696
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    Uniting the Global Gastroenterology Community to Meet the Challenge of Climate Change and Nonrecyclable Waste
    (2021) Leddin, Desmond; Omary, M. Bishr; Veitch, Andrew; Metz, Geoffrey; Amrani, Naima; Aabakken, Lars; Ali, Raja Affendi Raja; Alvares-Da-Silva, Mario Reis; Armstrong, David; Boyacioglu, Sedat; Chen, Ye; Elwakil, Reda; Fock, Kwong-Ming; Hamid, Saeed S.; Makharia, Govind; Macrae, Finlay; Malekzadeh, Reza; Mulder, Chris J.; Piscoya, Alejandro; Perman, Mai Ling; Sadeghi, Anahita; Saenz, Roque; Saurin, Jean-Christophe; Butt, Amna Subhan; Wu, Kaichun; Lee, Yeong Yeh; https://orcid.org/0000-0002-9370-1126; 34617932; AAE-7637-2021
    Climate change has been described as the greatest public health threat of the 21st century. It has significant implications for digestive health. A multinational team with representation from all continents, excluding Antarctica and covering 18 countries, has formulated a commentary which outlines both the implications for digestive health and ways in which this challenge can be faced.

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