Browsing by Author "Alaaddinoglu, Emine Elif"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    The Effect of Dental Pulp Stem Cells and L-PRF When Placed into The Extraction Sockets of Impacted Mandibular Third Molars on The Periodontal Status of Adjacent Second Molars: A Split-Mouth, Randomized, Controlled Clinical Trial
    (2023) Cubuk, Secil; Oduncuoglu, Bahar Fusun; Alaaddinoglu, Emine Elif; https://orcid.org/0000-0001-6718-3882; 35141806; AAH-5405-2020; F-3529-2010
    Purpose To compare the clinical and radiographic effectiveness of dental pulp stem cells (DPSCs) seeded onto L-PRF and L-PRF alone in the extraction socket of mandibular third molars. Methods This study analyzed 13 patients who required surgical removal of impacted bilateral mandibular third molars. The main outcome measures were the probing pocket depth (PPD) and clinical attachment levels (CAL) that were recorded for the adjacent second molars (LM2) at the baseline and 6 months after surgery. The secondary outcomes were radiographic vertical bone loss (VD) and relative bone density (rBD) distal to the LM2. Results Twenty-six LM2s were evaluated. After 6 months, the L-PRF and L-PRF + DPSC groups showed a significant reduction in PPD (1.65 +/- 1.01 mm and 1.54 +/- 0.78 mm) and CAL (2.23 +/- 1.45 mm and 2.12 +/- 0.74 mm), respectively. There was no difference between the groups for any periodontal parameters. No significant differences were found between the groups regarding the VD or rBD at the sixth month. Conclusions This study found that there was a significant improvement regarding the PPD, CAL, and VD measurements with the application of L-PRF, both alone and with the addition of DPSC, at the extraction socket. DPSC did not significantly contribute to the results compared to L-PRF therapy alone.
  • No Thumbnail Available
    Item
    Effects of Renal Transplantation and Hemodialysis on Patient's General Health Perception and Oral Health-Related Quality of Life: A Single-Center Cross-Sectional Study
    (2020) Oduncuoglu, Bahar Fusun; Alaaddinoglu, Emine Elif; Colak, Turan; Akdur, Aydincan; Haberal, Mehmet; 0000-0002-8726-3369; 0000-0002-8372-7840; 0000-0002-3462-7632; 0000-0003-0647-9481; 32113695; AAA-3068-2021; AAJ-8554-2021; AAJ-8097-2021; AAQ-4792-2020
    Background. Patients with end-stage renal disease have a lower quality of life compared to the general population. Oral health-related quality of life (OHRQoL) is of particular interest as good oral health could influence general health. This study aimed to compare dental and periodontal health status, OHRQoL, and general health perception of renal transplant (TX) and hemodialysis patients (HD) with that of healthy controls. Methods. The study included 64 TX, 63 HD, and 61 healthy patients. TX patients were also grouped according to the time elapsed after transplantation and currently use of immunosuppressive agents. The numbers of decayed, missing, and filled teeth were recorded as DMFT, and periodontal health status was evaluated. Patients' general health perceptions and OHRQoL were assessed using Short Form-36, Oral Health Impact Profile-14, and OHRQoL-United Kingdom questionnaires. Results. The HD groups presented significantly higher DMFT scores and periodontal scores than TX and control groups. OHRQoL-United Kingdom total scores of TX and HD groups were lower than controls (P < .05). Oral Health Impact Profile-14 total scores revealed that HD groups' OHRQoL was significantly lower than TX and control groups (P < .05). Perceptions of general health of TX patients were higher than in the HD group. Conclusions. Renal transplantation has shown to increase quality of life and OHRQoL compared to hemodialysis therapy. Neither the immunosuppressive agent nor the time elapsed after transplantation were observed to be significant factors affecting OHRQoL.