ARTICLE Course of the Wound Process With the Use of Modern Technologies in Local Treatment of Patients With Burns

Abstract

ABSTRACT

OBJECTIVES: We aimed to assess the wound-healing process using modern temporary wound dressings in local treatment of patients with burns. MATERIALS AND METHODS: From 2014 to the first half of 2022, the Department of Combustiology of the Republican Research Center of Emergency Medicine, Republic of Uzbekistan, conducted local treatment of 225 patients with superficial burns and 105 patients with deep IIIB/IV degree burns (age range, 1-60 years; mean age 17.5 ± 16.4 years). Most were children and adolescents (n = 146, aged 1-18 years); 79 were people of working age (age range, 19-60 years). The control group (115 patients with superficial burns, 55 patients with deep burns) received traditional local treatment using water-soluble ointments. The study group (110 patients with superficial burns, 50 patients with deep burns) received temporary wound dressings produced by New Dressing Materials CJSC, Russia (Parapran and Voskopran), with various options for local treatment. RESULTS: In 105 patients with deep burns, 122 necrectomy (early-delayed and delayed), 18 osteonecrectomy, and 134 autodermoplasty surgeries were performed. Fifty-two patients with traditional treatment received chemical necrectomy using 20% to 40% salicylic ointment. Less cases of toxic hepatitis, along with improving local reparative properties, were shown in patients who had active surgical tactics in the early stages after injury and temporary wound dressing than in the control group. Local treatment with temporary wound dressing in patients with extensive burns contributed to reduced purulent-septic complications, with no patients having burn sepsis. However, in severely burned patients in the control group, 3 patients (1.8%) had burn sepsis. CONCLUSIONS: Traditional methods of treatment are not acceptable for providing high-quality and qualified care for deep burns. Temporary wound dressings can reduce recovery time, being the most physiologically acceptable covering of burn surface wounds and achieving its main goal of early formation of granulation tissue, reducing secondary inflammatory processes.