Vitamin D Receptor Polymorphisms in Liver Transplant Recipients
| dc.contributor.author | Azarpira, Negar | |
| dc.contributor.author | Daraie, Masumeh | |
| dc.contributor.author | Geramizadeh, Bita | |
| dc.contributor.author | Salahi, Heshmatolah | |
| dc.date.accessioned | 2026-03-31T12:40:54Z | |
| dc.date.issued | 2010-12 | |
| dc.description.abstract | Objectives: Liver transplant is an established treatment for end-stage liver failure. Vitamin D has been shown to exert multiple immunomodulatory effects, which act through its own receptor (vitamin D receptor). In the present study, the association between Iranian patients with liver transplant and the polymorphism of vitamin D receptor FokI T>C (rs10735810) was investigated. Materials and Methods: The candidate gene locus was genotyped in 51 liver transplant recipients, and the association of each genotype with allograft acute rejection was evaluated. Results: In this study, we found no evidence to suggest that vitamin D receptor FokI polymorphism determines the incidence of acute rejection after liver transplant. The distribution of alleles was not different according to the underlying liver disease. Conclusions: Larger epidemiologic studies are needed to elucidate the importance of vitamin D receptor gene polymorphism in transplant recipients. | |
| dc.identifier.citation | Experimental and Clinical Transplantation, Cilt, 8, Sayı, 4, 2010 ss. 314-317 | en |
| dc.identifier.eissn | 2146-8427 | en |
| dc.identifier.issn | 1304-0855 | |
| dc.identifier.issue | 4 | en |
| dc.identifier.uri | https://hdl.handle.net/11727/14683 | |
| dc.identifier.volume | 8 | en |
| dc.language.iso | en | |
| dc.publisher | Başkent Üniversitesi | |
| dc.source | Experimental and Clinical Transplantation | en |
| dc.subject | Vitamin | |
| dc.subject | FokI | |
| dc.subject | genotype | |
| dc.subject | organ | |
| dc.subject | rejection | |
| dc.title | Vitamin D Receptor Polymorphisms in Liver Transplant Recipients | |
| dc.type | Article |