TR-Dizin İndeksli Açık & Kapalı Erişimli Yayınlar
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Item Demographic, epidemiologic and clinical characteristics of poisoning cases followed in pediatric intensive care unit(2020) Ozkale, Murat; Ozkale, Yasemin; 0000-0003-3009-336X; 0000-0003-0625-1057; AAL-6136-2021; A-7806-2016Purpose: This study was planned with the aim of retrospectively reviewing the demographic, epidemiologic and clinical characteristics of poisoning cases who treated in the pediatric intensive care unit and compare them with literature. Materials and Methods: The records of 581 patients admitted to the pediatric intensive care unit due to acute poisoning between 2015 and 2019 were retrospectively evaluated. Results: Five hundred and eightyone cases were enrolled in this study. The poisoned patients were aged between 3 months-18years and the female to male ratio was 1.6. Most poisonings occurred via the oral route (97.8%). It was noted that 57.1% of poisoning cases were accidental, whereas 39.1% were suicidal and 3.8% were a result of a therapeutic error. Eighty point nine percent of the cases were drug related while 19.1% were non-drug-related. Central nervous system drugs (%40.6) were the most common agent in drug-related poisoning, however rat poisons were the most common in non drug-related poisoning. The overall mortality rate in this study was 0.1%. Conclusion: Drug poisoning is the most common cause of poisoning in our region, which requires hospitalization, indicates that the society primarily should be raised more in this regard. In addition, we believe that our study will guide the physicians working in childhood poisoning patients who require hospitalization in our province and it ssurroundings, reflecting the epidemiological and clinical features and our results will contribute to updating the regional poisoning data.Item Peripheral Lymphadenopathy in Childhood: Single Center Study(2015) Ozkale, Yasemin; Ozkale, Murat; Sipahi, TansuPurpose: Lymphadenopathy is defined as an abnormality in the size and/or character of lymph node. In this study we aimed to describe the clinical and laboratory findings of benign and malignant causes of peripheral lymphadenopathy in childhood. Material and Methods: Two hundred and twenty four patients who were admitted to the clinic with peripheral LAP were evaluated. Age, gender, laboratory and radiologic findings, final diagnoses, and duration, localization, size, consistency, spread, and accompanying local and systemic symptoms of LAP were determined. Benign and malignant causes of peripheral lymphadenopathy were compared. Results: One hundred twenty-six patients (56.0%) were male and 98 patients (44.0%) were female. After the first evaluation the patients were divided into two groups. The first group included 186 patients with benign causes and the second group included 38 patients with malignant causes. One hundred and sixty four of 224 patients (73.2 %) had localized peripheral lymphadenopathy. The most frequent cause of localized lymphadenopathy in the benign group was acute lymphadenitis (34.8%). The most common cause of localized lymphadenopathy in the malignant group was Hodgkin's lymphoma (4.3%). Sixty of 224 (26.8%) patients had generalized peripheral lymphadenopathy. The most significant cause of generalized lymphadenopathy in the benign lymphadenopathy group was Epstein-Barr virus (10.0%), whereas Hodgkin's lymphoma (23.3%) was the most common cause in malign lymphadenopathy group. Localized and generalized lymph node enlargement was most frequently found in cervical region. The most frequent site of involvement among benign and malignant cases was the cervical area. The results revealed that findings such as chronic course, generalized LAP, supraclavicular, cervical and inguinal location, organomegaly, hilier LAP, abdominal LAP, and abnormal laboratory findings (thrombocytopenia and blasts on the peripheral blood smear) were associated with malignant diseases. Conclusion: Infections are the most common cause of peripheral LAP. The risk of malignany increases with the age of child and the duration of LAP. Older children with chronic LAP, generalized LAP associated with organomegaly, abnormal laboratory findings should be considered as malignant LAP.Item Sadfly fever: two case reports(2016) Ozkale, Yasemin; Ozkale, Murat; Kiper, Pinar; Cetinkaya, Bilin; Erol, Ilknur; 0000-0002-3530-0463; 0000-0003-0866-7339; 0000-0003-3009-336X; 0000-0003-0625-1057; 27489469; AAK-4825-2021; AAF-1346-2021; AAL-6136-2021; A-7806-2016Sandfly fever, also known as 'three-day fever' or 'pappataci fever' or 'Phlebotomus fever' is a viral infection that causes self-limited influenza-like symptoms and characterized by a rapid onset. The disease occurs commonly in endemic areas in summer months and especially in August during which sandflies are active. In this article, two siblings who presented with high fever, redness in the eyes, headache, weakness, malaise and inability to walk, who were found to have increased liver function tests and creatine kinase levels and who were diagnosed with sadfly fever with positive sadfly IgM and IgG antibodies are reported because of the rarity of this disease.Item Narcolepsy and cataplexy: a pediatric case report(2016) Erol, Ilknur; Savas, Tulin; Saygi, Semra; Habesoglu, Mehmet Ali; 0000-0002-3530-0463; 0000-0002-8522-5078; 0000-0001-9136-355X; 28123336; AAK-4825-2021; Q-2338-2019; AAB-1203-2021Narcolepsy is characterized by excessive sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis during the rapid eye movement period of sleep. Herein, we present a boy aged eight years who was diagnosed as having narcolepsy and cataplexy about thirteen months after his first presentation. He was admitted with symptoms of daytime sleepiness. In the follow-up, cataplexy in the form of head dropping attacks developed seven months after the first admission. The patient was investigated for different prediagnoses and was eventually diagnosed as having narcolepsy and cataplexy through polysomnography and multiple sleep latency tests thirteen months after the first presentation. He is being followed up and is under drug therapy; his symptoms have improved substantially.Item Post-traumatic Delayed Peripheral Facial Palsy(2018) Kansu, LeylaPeripheral facial palsy in children is very rare in comparison to adults. The most common cause is idiopathic. Another rare cause of peripheral facial palsy in children is trauma. It occurs after head trauma, mostly due to temporal bone fracture as an early onset paralysis after trauma. Early onset facial palsy is usually due to direct damage to the facial nerve whereas there is some controversy about the etiology of late onset facial palsy. In this article, a child patient whose peripheral facial palsy developed six days after a head injury is presented, and the etiopathogenesis and the treatment of delayed traumatic facial palsy after temporal bone fracture is discussed.