TR-Dizin İndeksli Açık & Kapalı Erişimli Yayınlar
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Item The prognostic value of mean apparent diffusion coefficient measured with diffusion-weighted magnetic resonance image in patients with prostate cancer treated with definitive radiotherapy(2022) Onal, Cem; Erbay, Gurcan; Guler, Ozan Cem; Oymak, Ezgi; 35753556Purpose: To assess the correlation between initial tumor apparent diffusion coefficient (ADC) values and clinicopathological parameters in prostate cancer (PCa) patients treated with definitive radiotherapy (RT). Additionally, the prognostic factors for freedom from biochemical failure (FFBF) and progressionfree survival (PFS) in this patient cohort were analyzed. Materials and methods: The clinical data of 503 patients with biopsy-confirmed PCa were evaluated retrospectively. All patients had clearly evident tumors on diffusion-weighted magnetic resonance imaging (DW-MRI) for ADC values. Univariable and multivariable analyses were used to determine prognostic factors for FFBF and PFS. Results: The median follow-up was 72.9 months. The 5-year FFBF and PFS rates were 93.2% and 86.2%, respectively. Significantly lower ADC values were found in patients with a high PSA level; advanced clinical stage; higher ISUP score, and higher risk group than their counterparts. Receiver operating characteristic (ROC) curve analysis revealed an ADC cut-off value of 0.737 x 10-3 mm2/sec for tumor recurrence. Patients who progressed had a lower mean ADC value than those who did not (0.712 +/- 0.158 vs. 1.365 +/- 0. 227 x 10-3 mm2/sec; p < 0.001). There was a significant difference in 5-year FFBF (96.3% vs. 90%; p < 0.001) and PFS rates (83.8% vs. 73.5%; p = 0.002) between patients with higher and lower mean ADC values. The FFBF and PFS were found to be correlated with tumor ADC value and ISUP grades in multivariable analysis. Additionally, older age was found to be a significant predictor of worse PFS. Conclusions: Lower ADC values were found in patients with high-risk characteristics such as a high serum PSA level, stage or grade of tumor, or high-risk disease, implying that ADC values could be used to predict prognosis. Lower ADC values and higher ISUP grades were associated with an increased risk of BF and progression, implying that treatment intensification may be required in these patients. (c) 2022 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 173 (2022) 285-291Item Retroperitoneal abscess and duodenal (enterocutaneous) fistula due to brucella(2016) Karadeli, Elif; Erbay, Gurcan; 0000-0002-0352-8818; 0000-0002-1706-8680; AAK-5399-2021; AAK-5370-2021Duodenal fistula is rarely seen. It occurs after gastric, aort, bowel operation, or trauma and foreign body perforastion. In this case report we present abdominal tomography findings of duodenal (enterocutaneous) fistula due to brucella.Duodenal fistula is rarely seen. It occurs after gastric, aort, bowel operation, or trauma and foreign body perforastion. In this case report we present abdominal tomography findings of duodenal (enterocutaneous) fistula due to brucella.Item Late pancreatic metastasis of renal cell carcinoma with absence of FDG-uptake in PET-CT(2016) Karadeli, Elif; Tok, Sermin; Erbay, Gurcan; Reyhan, Mehmet; 0000-0002-1706-8680; 0000-0002-0352-8818; 0000-0001-8550-3368; AAK-5370-2021; AAK-5399-2021; AAJ-5242-2021The primary tumors, which raise isolated pancreas metastases are frequently of renal origin, where colorectal cancer, melanoma, breast and lung cancers and sarcoma are the following causes of metastatic pancreas cancer. In this article, we present a case of pancreas-metastatic renal cell carcinoma with its radiological features, which did not exert anF-18 FDG-uptake in the whole-body positron emission tomography (PET).Item Radiologic findings mimicking acute abdomen in a patient with colorectal cancer: are these side effects of FOLFIRI therapy?(2016) Karadeli, Elif; Erbay, Gurcan; Koc, Zafer; 0000-0002-1706-8680; 0000-0002-0352-8818; 0000-0003-0987-1980; AAK-5370-2021; AAK-5399-2021; S-8384-2016Bowel perforation is an emergency problem, it presents as an acute abdomen. Computurize tomography (CT) is important imaging modality used to evaluate patients with acute abdomen. CT shows anatomical detail and intestinal wall, evaluating secondary signs of bowel disease within the surrounding mesentery and detecting even small amounts of extraluminal air or oral contrast leakage into the peritoneal cavity. The aim of this article is to illustrate acute abdominal CT findings due to FOLFIRI therapy of a patient with colorectal cancer. Interestingly, this patient was an emergency case based on radiologic findings, but he felt good, had no emergency problem clinically.Item Perforation without manifestations of acute abdomen after ERCP(2016) Karadeli, Elif; Tok, Sermin; Erbay, Gurcan; 0000-0002-0352-8818; 0000-0002-1706-8680; AAK-5399-2021; AAK-5370-2021Perforations are rare after endoscopic retrograde cholangiography (ERCP) but they are serious complications. Perforations may occur due to patient-related factors or procedural technique. The mortality rate is higher than 37.5%. We are presenting a patient with perforation detected on a computed tomography (CT) scan after ERCP for obstructive jaundice that was treated conservatively. Perforation after ERCP can be operated or treated conservatively according to the patient's condition.Item Retroperitoneal Schwannoma: A Case Report(2017) Ozer, Cevahir; Goren, Mehmet Resit; Hasbay, Bermal; Erbay, Gurcan; 0000-0002-7850-6912; 0000-0002-2001-1386; 0000-0002-1706-8680; AAM-2222-2020; Y-6143-2019; AAK-5370-2021Schwannomas are benign tumors originating from Schwann cells of the neural sheaths. Only 0.3% to 3% of the schwannomas are located the retroperitoneal space. Most schwannomas are asymptomatic and often found incidentally. The ideal treatment is complete surgical excision. Here, we report a case of a 49-year-old woman with retroperitoneal schwannoma.Item Cystic lymphangioma of the ascending colon and cecum(2018) Karadeli, Elif; Erbay, Gurcan