TR-Dizin İndeksli Açık & Kapalı Erişimli Yayınlar
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Item Chanarin Dorfman Syndrome: A Case Report(2015) Ozkale, Yasemin; Erol, Ilknur; Canan, Oguz; Durdu, MuratChanarin Dorfman Syndrome is a multisystem inherited metabolic disorder associated with congenital ichthyosis and accumulation of lipid droplets in varios types of cells. Observation of lipid vacuoles in neutrophils (Jordan's anomaly) in peirpheral blood smears in patients with ichthyosis is diagnostic for Chanarin Dorfman Syndrome. Since the initial case was reported by Dorfman in 1974, nearly 50 cases have been reported in the literature, and the majority were from Middle East countries. In this report we presented a 5 year old patient who admitted to our hospital for creatine kinase elevation and diagnosed as Chanarin Dorfman Syndrome with clinical and laboratory findings.Item Cytology in the Diagnosis of Dermatological Diseases: Tzanck Smear(2016) Durdu, Murat; 0000-0003-1247-3932; H-9068-2019Cytology is a simple, quick, reliable, and inexpensive diagnostic method based on the investigation of characteristic features of individual cells. In this diagnosis method, cellular materials are obtained by scraping method, slit-skin smear, touch smear or fine needle aspiration method according to the types of skin lesions. Obtained materials are immediately spread onto microscopic slide as a thin layer. Slides were stained with various cytological dyes, and examined under the light microscope. Until today, dermatological cytology has been used in the diagnosis of various erosive-vesiculobullous, pustular, granulomatous, and tumoral skin lesions. In this review article, the sampling methods for dermatological cytology were described, and the cytologic findings of skin diseases which could provide a rapid diagnosis were discussed.Item Role of Latex Hypersensitivity in Patients with Chronic Urticaria(2016) Durdu, Murat; Seckin, Deniz; 0000-0003-1247-3932; H-9068-2019Objectives: In this study, we aimed to determine the frequency of latex hypersensitivity in patients with chronic urticaria and to investigate the effect of latex-cross reacting food on the clinical course of the disease. Methods: This study includes 100 patients who admitted to our dermatology clinic with chronic urticaria, 100 health care providers and 100 healthy individuals. In patients with chronic urticaria, latex skin prick test was performed in addition to routine laboratory investigations. In the control group, prick test was performed only with latex. Changes in urticaria activity scores before and after latex containing products and cross reacting food restrictions were statistically compared in patients with urticaria. Results: Latex skin prick test was positive in 4 (4%) patients with urticaria and in 10 (10%) health care providers. Positive reaction was not observed in the healthy control group. Latex hypersensitivity in patients of urticaria was higher than healthy individuals, but the difference was not statistically significant. Urticaria activity scores did not change significantly after avoiding latex-cross reacting foods and latex-containing products. Conclusion: Latex hypersensitivity in patients with chronic urticaria was not found to be higher than the healthy individuals. In latex-sensitive patients, avoidance of latex-cross reacting foods and latex-containing products do not change the clinical course of the disease.Item Quick cytological diagnosis and rapid improvement with imiquimod cream in a case of orf infection(2016) Durdu, MuratOrf is a viral infection caused by the orf virus known to be the largest DNA virus that belongs to the Parapoxvirus genus. The disease occurs 3-7 days after contact with sheep and goats. Lesions usually resolve spontaneously within 6-8 weeks. On the other hands, infection may show progressive course in immunosuppressed patients. It has been reported that imiquimod cream can provide rapid improvement. We present the case report of a 48-year-old woman who developed erythematous nodular lesions two days after contact with animal. Tzanck smear examination was performed from nodular lesion, and cytoplasmic inclusions (Guarnieri bodies) were detected. The lesion rapidly resolved with topical imiquimod cream.