TR-Dizin İndeksli Açık & Kapalı Erişimli Yayınlar

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    Tru-cut biopsy in cryptogenic organizing pneumonia
    (2015) Balcan, Baran; Olgun, Sehnaz; Sagmen, Seda Beyhan; Bagci Ceyhan, Berrin
    Cryptogenic organizing pneumonia (COP) was first described by Davison and colleagues in 1983. Previously, it was called bronchiolitis obliterans organizing pneumonia (BOOB). The following are known causes of COP: toxic gas inhalation, chemotherapy, radiation therapy, aspiration, blood transfusion, upper respiratory tract infections, or it can be idiopathic. The clinical features of the patients resemble those of pneumonia or upper respiratory tract infection. In COP, imaging scans of the lungs reveal diffuse migrating patchy infiltrations which are in contact with the pleura. Corticosteroids are the first choice for treatment, but in some patients other immunosuppressive drugs are needed. Low doses may result in relapses. Transbronchial biopsy has a low yield in the diagnosis, instead tru-cut biopsy is the first choice for a definitive diagnosis. In this paper, we define our experience with two patients from whom we obtained a tru-cut lung biopsy in order to reach for a diagnosis.
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    Wegener Granulomatosis Complicated by Brain Abscess Caused by Nocardia spp.
    (2016) Sahin, Sevgi; Balcan, Baran; Kiziltas, Safak; Aydin, Mehtap; Y-1366-2018; A-4721-2018
    Wegener granulomatosis is a multisystemic disease associated with high mortality rate and characterized by necrotizing granulomatous vasculitis predominantly in the respiratory tract and kidneys. Presence of kidney failure at the time of diagnosis describes a poor prognostic marker. We presented a Wegener granulomatosis case complicated with brain abscess caused by Nocardia.
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    Results of Polysomnographies and Treatment Strategies in Elderly Patients with Symptoms of Obstructive Sleep Apnea Syndrome
    (2017) Ugurlu, Aylin Ozsancak; Balcan, Baran; 0000-0003-3598-3986; 29404173; A-4721-2018; AAA-2925-2020
    OBJECTIVES: In this study, we evaluated data regarding the management of geriatric patients with symptoms of obstructive sleep apnea syndrome (age, >65 years) who were admitted to our sleep clinic. MATERIAL AND METHODS: Symptoms and sleep data of the patients were retrospectively evaluated, and the patients were reevaluated after treatment. RESULTS: A total of 85 patients with a median age of 69 years were included. Snoring and fatigue were the most common symptoms. Cardiovascular diseases were the most frequently listed comorbidity. The median Epworth sleepiness scale was 10, and based on Berlin sleep questionnaire findings, 63.5% of the participants were in the high-risk group. Eighty-seven percent were diagnosed with obstructive sleep apnea (2/3 of them were positional), and moderate-to-severe obstructive sleep apnea was observed more in women than in men. Only one patient was diagnosed with central sleep apnea. There were positive and linear correlations between increased age and the apnea-hypopnea index, arousal index, Epworth sleepiness scale, and being in a high-risk group according to the Berlin sleep scale; however, there was no correlation between increased age and the number of hypopnea and apnea events. There were also positive and linear correlations between the apnea-hypopnea index and the Epworth sleepiness scale, being in a high-risk group according to the Berlin sleep questionnaire, an increased number of known medical conditions, and increased body mass index. We were able to contact 72 of the 85 patients via phone calls. Patients who adjusted to treatment had positive feedbacks. CONCLUSION: Sleep disorders are observed more in the elderly, and an increasing age is an independent factor for sleep disorders. Besides the usual signs and symptoms of sleep disorders, it should be considered in elderly who have cognitive dysfunction and dementia.
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    Altered pulmonary functions due to biomass smoke in a rural population of Turkish women: a descriptive study
    (2018) Ozsancak Ugurlu, Aylin; Balcan, Baran; Akan, Selcuk; Ceyhan, Berrin; 30246655; A-4721-2018
    Introduction: Wood or other organic sources of fuel are used as source of energy for heating or cooking particularly in developing countries. The aim of the current study was to evaluate the association between biomass exposure time and parameters of pulmonary function tests. Materials and Methods: Four hundred twenty-four consecutive women who lived and exposed to biomass smoke in a small province in Eastern Turkey were involved. This study was performed with women who had come to pulmonology out-patient clinic with symptom of dyspnea. Results: The independent variables assessed in the study patients were age, BMI, starting age of cooking, hours per day and weeks per month spent cooking, and cooking years; the dependent variables were PFT parameters. Ninety-two (21.6%) patients had an obstructive PFT pattern. Sixty-seven (73%) of these patients were classified as GOLD 2 and 25 (27%) patients were classified as GOLD 3. Seventy-five (17.6 %) of the patients had restrictive lung disease; 54 (72%) of these patients were found to have a mild and 21 (27%) had a moderate restrictive pattern. Increased number of years in cooking and to start cooking at younger ages were a risk factors for the development of obstructive and restrictive disease. There was a statistically significant and negative correlation between increased number of years and the value of FEV1 (r=-0.917; p=<0.001), FEV1/FVC (r=-0.739; p<0.001), and FVC (r=-0.906; p<0.001). The median time of cooking required was 23 years for the development of obstruction, and 25 years for restriction, respectively. Conclusion: Cumulative biomass exposure time is associated with impairment in PFT parameters; results in both obstructive and restrictive lung disease. Biomass exposure is a public health problem and pre-cautions should be taken in order to prevent impaired pulmonary functions.