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    POLYPHARMACY PREVALENCE AMONG GERIATRIC PATIENTS IN PRIMARY HEALTHCARE SETTINGS ACROSS TURKEY: A CROSS-SECTIONAL ANALYSIS THROUGH THE NATIONWIDE PRESCRIPTION INFORMATION SYSTEM
    (2020) Aydos, ToIga Resat; Emre Aydingoz, Selda; Lux, Karl Michael; Efe, Oguzhan Ekin; Isli, Fatma; Aksoy, Mesil; Kadidoi, Esma; 0000-0002-3243-7843; 0000-0002-1832-9336; 0000-0001-7823-7620; W-7908-2019; AAJ-7279-2020; ABA-4291-2020
    Introduction: Polypharmacy has become a common health problem as populations age. We aimed to determine the prevalence of chronic and cumulative polypharmacy in the geriatric population using primary healthcare services in Turkey. Materials and Methods: The electronic prescriptions ordered by family physicians across Turkey for geriatric patients (>= 6.5 years) in the Prescription Information System during 2018 were studied. Chronic polypharmacy criteria were proportion of patients who were given prescriptions containing >= 5 drugs four or more times during a year. Cumulative polypharmacy was defined as proportion of patients who were prescribed >= 5 drugs with different ATC4 codes in a month or in each quarter of the year. Results: Turkey's total population is 82 million; 7,186,204 are aged 65 and over, constituting 8.8% of the total. Of this geriatric population, 6,104,798 (85.0%) had at least one prescription in 2018. Each geriatric patient had 6.4 prescriptions, with each prescription containing an average of 2.9 drugs with different fourth-level Anatomical Therapeutic Chemical codes. Each drug was prescribed in 2.7 boxes on average. Of these prescribed patients, 14.3% received prescriptions containing >= 5 drugs four or more times during 2018. The percentage of patients who received at least one prescription per month containing >= 5 drugs ranged between 16.4% and 20.7%. The most commonly prescribed drugs were acetylsalicylic acid, diclofenac, paracetamol, and pantoprazole. Conclusion: Polypharmacy is a critical health problem among geriatric population in Turkey as in other industrialized countries. Educating physicians as well as the public is essential to overcome polypharmacy.
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    FREQUENCY OF POLYPHARMACY AND RISK FACTORS IN THE ELDERLYIN BURDUR
    (2018) Durukan, Elif; Onal, Ozgur
    Introduction: Polypharmacy is common among the elderly. This study aimed to determine the frequency of polypharmacy and the risk factors in the elderly. Materials and Method: This cross-sectional study will be analysed in three stages (polypharmacy, drug characteristics and drug interaction). Herein, the first stage (polypharmacy) was conducted at Burdur city centre and the connected villages. A total of 400 of 11,360 subjects aged >= 65 years who were registered with family physicians in Burdur city centre were selected using a systematic sampling method. A questionnaire of 30 questions about socio-demographic variables and rational drug use was distributed among the subjects. Subsequently, the subjects were asked to bring their own drugs from home that they were actively using or not currently using, and their drug-using behaviour was analysed via specific questions. Results: The average number of different drugs possessed by the subjects at home was approximately 6 (5.95 +/- 4.30). A total of 64.9% of the drugs were used regularly, 21.3% were used occasionally and 13.8% were previously used but not currently used. The median number +/- standard deviation of the drugs that were used regularly, used occasionally and previously used but not currently used was 3.86 +/- 3.36, 1.27 +/- 1.75 and 0.82 +/- 1.82, respectively. According to the results of multivariate analysis, the presence of diabetes, hypertension, respiratory system or cardiovascular (except hypertension) diseases, visual impairment or hearing disorders significantly increased the total drug use (p<0.05). Conclusion: Chronic diseases and living in the city centre are the main risk factors leading to polypharmacy. Therefore, interventions must be undertaken by monitoring and reducing chronic diseases and providing training on rational drug use in the provincial centres.