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Item Complications and specimen quality in transrectal ultrasound guided prostate biopsy: Comparison of 16G and 18G needles(2020) Bayraktar, Ahmet Murat; Olcucuoglu, Erkan; Hasirci, Eray; Nalbant, Ismail; Yesil, Suleyman; 0000-0002-4147-2966; AAI-7997-2021Objectives: To evaluate specimen quality, pathological results, complications and pain in transrectal ultrasound (TRUS) guided prostate biopsy using 16 gauge (G) or 18G biopsy needles Design: Retrospective study Setting: Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey Subjects: Retrospective analysis of 243 TRUS guided prostate biopsies between March 2011 and April 2016 Interventions: Group 1 (n=121) underwent TRUS guided prostate biopsy using a 16 G needle and Group 2 (n=122) underwent TRUS guided prostate biopsy with an 18 G-needle. Main outcome measures: We compared two biopsy needle sizes (16G vs 18G) in relation to sample quality, prostate cancer detection rate, pain, bleeding and infection rates in 243 patients. Core fragmentation and short specimen length (<10mm) rate were the sample quality criteria. Pain was evaluated using visual analog scale (VAS). Results: There were no statistically significant differences in mean patient ages, prostate-specific antigen values and prostate volumes between groups 1 and 2. Sixteen gauge needles caused significantly less fragmentation of the biopsy cores when compared to 18G needles (p=0.00), but no statistically significant difference between two groups was recorded for pathological results (p=0.72) and shorter specimen length (p=0.567). Haematuria, rectal bleeding and infection were similar in both groups. Mean VAS score of group 1 was significantly greater than that of group 2 (3.19 vs 2.66;p=0.027). Conclusion: Though thicker needles provided better sampling quality, the cancer detection rate was not altered by the needle size. Also, even though complication rates were similar for different needle sizes, the 18G needles were better tolerated.Item Cancer detection rates of different prostate biopsy regimens in patients with renal failure(2014) Hoscan, Mustafa Burak; Ozorak, Alper; Oksay, Taylan; Perk, Hakki; Armagan, Abdullah; Soyupek, Sedat; Serel, Tekin Ahmet; Kosar, AlimWe aimed to evaluate the cancer detection rates of 6-, 10-, 12-core biopsy regimens and the optimal biopsy protocol for prostate cancer diagnosis in patients with renal failure. A total of 122 consecutive patients with renal failure underwent biopsy with age-specific prostate-specific antigen (PSA) levels up to 20 ng/mL. The 12-core biopsy technique (sextant biopsy + lateral base, lateral mid-zone, lateral apex, bilaterally) performed to all patients. Pathology results were examined separately for each sextant, 10-core that exclude parasagittal mid-zones from 12-cores (10a), 10-core that exclude apex zones from 12-cores (10b) and 12-core biopsy regimens. Of 122 patients, 37 (30.3%) were positive for prostate cancer. The cancer detection rates for sextant, 10a, 10b and 12 cores were 17.2%, 29%, 23.7% and 30.7%, respectively. Biopsy techniques of 10a, 10b and 12 cores increased the cancer detection rates by 40%, 27.5% and 43.2% among the sextant technique, respectively. Biopsy techniques of 10a and 12 cores increased the cancer detection rates by 17.1% and 21.6% among 10b biopsy technique, respectively. There were no statistical differences between 12 core and 10a core about cancer detection rate. Adding lateral cores to sextant biopsy improves the cancer detection rates. In our study, 12-core biopsy technique increases the cancer detection rate by 5.4% among 10a core but that was not statistically different. On the other hand, 12-core biopsy technique includes all biopsy regimens. We therefore suggest 12-core biopsy or minimum 10-core strategy incorporating six peripheral biopsies with elevated age-specific PSA levels up to 20 ng/mL in patients with renal failure.