Scopus İndeksli Açık & Kapalı Erişimli Yayınlar
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Item Influence of Orthognathic Surgery on Oral Health and Quality of Life(2022) Tuz, Hakan Hifzi; Ergezen, Ezgi; Meral, Salih Eren; Ekmekcioglu, Aylin; El, Hakan; 33867509Orthognathic surgery is a common treatment modality for moderate to severe dentofacial deformities. This study aimed to determine the early postoperative changes in quality of life (QoL) after orthognathic surgery. Twenty patients were evaluated preoperatively (T0), postoperatively after 1 month (T1), and postoperatively after 3 months (T2). Short Form Oral Health Impact Profile and Orthognathic Quality of life Questionnaire were used as generic oral health-related and condition-specific QoL measures. Oral Health Impact Profile -14 and Orthognathic Quality of life Questionnaire scores significantly decreased from T0-T2. Physical pain, psychological disability, social disability, and handicap scores significantly decreased during this interval. Facial esthetic, function, awareness of facial deformity, and social aspects of deformity were also found to significantly improve. No significant difference was found between age groups; female patients had significantly greater preoperative Oral Health Impact Profil-14 scores than did male patients. Orthognathic surgery not only enhances the skeletal and facial relations, but also has significant positive effects on the patients' QoL, oral health, and psychological status.Item Factors Associated with Kinesiophobia in Patients with Knee Osteoarthritis(2022) Acar, Manolya; Sonmezer, Emel; Yosmaoglu, H. BaranPurpose This study aims to determine factors affecting kinesiophobia in patients with knee osteoarthritis (OA). Materials and Methods The fear of movement was measured using the Tampa Scale of Kinesiophobia in 60 patients with knee OA. Pain intensity was assessed with the Visual Analog Scale, quality of life with the Nottingham Health Profile (NHP), disability with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), anxiety and depression with the Hospital Anxiety and Depression Scale (HADS), balance with the Berg Balance Scale, mobility with the Timed Up and Go Test, and the physical activity status was measured with the International Physical Activity Questionnaire. Results Physical mobility and emotional reactions subscales of NHP, all WOMAC subscales and the HADS depression subscale were significantly related to kinesiophobia. Muscle strength, ROM, level of physical activity, balance, mobility and anxiety were not significantly related to kinesiophobia. Quality of life and disability explained 34.4% of the variation in the Tampa Scale of Kinesiophobia. Conclusions Kinesiophobia was associated with quality of life, disability and depression. It may be useful for clinicians to pay attention to the evaluation of psychosocial characteristics instead of physical performance parameters in order to increase treatment success in OA patients.Item Improvement of Work Productivity and Quality of Life with Anti-Tumor Necrosis Factor Treatment Used in Crohn's Disease in Routine Clinical Practice in Turkey(2022) Toruner, Murat; Basaranoglu, Metin; Atug, Ozlen; Senturk, Omer; Akyuz, Filiz; Cekic, Cem; Hamzaoglu, Hulya Over; Tekin, Fatih; Sezgin, Orhan; Akpinar, Hale; Celik, Aykut Ferhat; Tezel, Ahmet; Gokturk, Huseyin Savas; Kav, Taylan; 35678798Background: Patients with Crohn's disease experience major deterioration in work productivity and quality of life. We aimed to provide the long-term effects of anti-tumor necrosis factor agents on work productivity and activity impairment and quality of life in patients with Crohn's disease using the Inflammatory Bowel Disease Questionnaire and the Short-Form Health Survey-36. Methods: Patients with Crohn's disease and initiated an anti-tumor necrosis factor treatment were included and followed up for 12 months in this observational study. Results: A total of 106 patients were included in this study, and 64.2% of the patients were males. Mean [+/- standard deviation] age was 36.8 [+/- 10.9] years. At baseline, mostly perianal fistulas [65.7%] were observed [n = 23]. Intestinal stenosis was detected in 34.9% of the patients [n = 37], and most of the stenosis was located in the ileum [70.6%] followed by the colon [20.6%]. Extraintestinal symptoms were observed in 24 patients [22.6%]. Most frequent extraintestinal symptom was arthritis with 71.4% [n = 15]. Mean time from first symptom to initiation of anti-tumor necrosis factor treatment was 6.3 [+/- 5.0] years. Improvements in work productivity and activity impairment scores throughout 12 months were -24.1% [P =.003] for work time missed, -18.0% [P =.006] for impairment at work, -8.5% [P =.160] for overall work impairment, and -17.0% [P <.001] for daily activity impairment. Similarly, significant improvements [P <.001] were detected in all components of the Inflammatory Bowel Disease Questionnaire when compared to baseline. Statistically significant improvements [P <.05] were detected for all components of Short-Form Health Survey-36 except for mental health [P =.095]. Conclusion: Our study indicates the significant improvement in work productivity and activity impairment and quality of life of patients with Crohn's disease who receive long-term anti-tumor necrosis factor treatment.Item Foot Deformity in Patients With Ankylosing Spondylitis: Is It Associated With Functionality and Disease Activity?(2022) Guzel, Sukran; Umay, Ebru; Ozturk, Erhan Arif; Gurcay, Eda; 0000-0001-9852-0917; 35227596; AAG-3148-2021Foot involvement affects mobility and functionality in patients with ankylosing spondylitis but it remains unknown if foot deformities in ankylosing spondylitis patients affect functionality, disease activity, and quality of life. The aim of this study was to evaluate in detail the presence of a relationship between radiologically detected foot deformities in ankylosing spondylitis patients and both clinical and electro-physiological findings. The cross-sectional study included 110 patients with ankylosing spondylitis who were diagnosed according to the Assessment in Spondyloarthritis International Society criteria and were followed in our hospital. Demographic and clinical data of all patients were recorded. Bilateral lateral foot x-rays and electrophysiology examinations were evaluated in all subjects. The arch in the dominant foot of the patients was classified in 3 groups as pes cavus, pes planus, or normal. The clinical outcomes, phys-ical examination and electrophysiological findings were compared between the groups, and correlations were examined of the foot deformities with these parameters. Foot deformities were determined at a high rate (74.5%). These deformities affected foot pain, disability and quality of life. Pes cavus deformity was found to be associated with hip pain and enthesopathy. In the electrophysiological studies, the pres-ence of pes planus was found to be associated with the findings of the tibial and sural nerve conduction studies, and the presence of pes cavus with the findings of the peroneal nerve conduction study. In con-clusion, foot deformities may have an effect on the quality of life and functionality in ankylosing spondy-litis patients. (c) 2022 by the American College of Foot and Ankle Surgeons. All rights reserved.Item Evaluation of the Effect of Periodontitis on Quality of Life Using Oral-Dental Health-Related Quality of Life-United Kingdom Scale(2021) Kutsal, Derya; Cetin, Mehtap Bilgin; Durukan, Elif; Bulut, Sule; 0000-0002-8579-5564; 33797852; AAJ-8621-2021Objective The aim of this study was to investigate the impact of periodontitis on oral health-related quality of life (OHQoL) using Oral-Dental Health-Related Quality of Life-United Kingdom (OHRQoL-UK) scale and evaluate the contributing factors. Methods 50 patients with untreated periodontitis and 50 individuals without periodontitis were enrolled in the study. All subjects received detailed periodontal examination. Plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) measurements were examined. OHRQoL was assessed by the Oral Health Quality of Life-United Kingdom (OHRQoL-UK) scale. Symptoms of periodontitis were monitored by visual analogue scale (VAS). Socio-demographic characteristics, medical history, smoking status, hygiene habits of the participants were recorded. This study is registered at ClinicalTrials.gov as NCT04240014. Results Total OHRQoL-UK scores were 38.24 +/- 6.47 in periodontitis patients and 55.88 +/- 9.38 in non-periodontitis individuals (p < 0.001). The scores of all 4 parameters were significantly lower in patients with periodontitis compared to healthy individuals (p <0.001). Higher PI, GI, PD and CAL values were associated with extensive negative impacts of periodontitis on OHRQoL (p < 0.001). According to the results of linear regression analysis, only periodontitis was found to associate with OHRQoL. Periodontal disease reduces the total quality of life score by 15.087 (ss= -15.087; 95% CI = [(-18.934)-(-11.240)]. Conclusions Individuals with periodontitis has diminished OHRQoL compared to healthy individuals.Item Functional electrical stimulation cycling in patients with chronic spinal cord injury: a pilot study(2021) Gurcay, Eda; Karaahmet, Ozgur Zeliha; Cankurtaran, Damla; Nazli, Fatma; Umay, Ebru; Guzel, Sukran; Gurcay, Ahmet Gurhan; 0000-0001-9852-0917; 33998960; AAG-3148-2021Objective To examine the therapeutic value of lower extremity functional electrical stimulation (FES) - evoked cycling on functional independence, health status, gait parameters, pulmonary functions, and biochemical values in patients with chronic complete/incomplete spinal cord injury (SCI). Materials and Methods Fifteen patients with SCI (duration of more than 6 months) who were able to stand up and walk with long leg braces or assistive devices and had stable neurological status and trunk balance undertook FES cycling for 6 weeks (three times per week). The main outcomes were: Functional Independence Measure (FIM), Nottingham Health Profile (NHP), 6-minute walk test (6MWT), and 20-meter walk test (20MWT). Secondary outcomes include measurements of pulmonary function tests and biochemical values. All parameters were evaluated at the beginning and end of the program. Results Improvements were seen in motor and total scores of FIM (p = 0.007), physical mobility subscale of NHP (p = 0.011), 6MWT (p = 0.001), and 20MWT (p = 0.011). In pulmonary functions, only forced vital capacity (FVC) levels demonstrated a significant increase compared with baseline (p = 0.011). Biochemical values reached no significant level. Conclusion The results of this study showed that the FES cycling exercise program improves motor and total FIM scores, gait parameters, and FVC values of pulmonary functions in patients with chronic SCI experience. The FES cycle might be a valuable and well-tolerated intervention in clinical rehabilitation.Item Impact of stage-grade of periodontitis and self-reported symptoms on oral health-related quality of life(2021) Yilmaz, Mediha Nur Nisanci; Bulut, Sule; Bakirarar, Batuhan; 0000-0002-6410-2060; 34478610Objectives The aim of the study was to investigate the impact of stage-grade of periodontitis and self-reported signs and symptoms on oral health-related quality of life. Methods The diagnosis of periodontitis was based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. The Turkish version of Oral Health Impact Profile-14 (OHIP-14) was used to assess oral health-related quality of life (OHRQoL) and the participants were requested to state their symptoms associated with periodontal diseases. Results One hundred and sixty-six patients were included in the study with a mean age of 46.54 +/- 9.24 years. The participants with Stage IV and Grade C periodontitis had the highest total OHIP-14 scores (median 20.00 [min.-max, 3.00-35.00] and median 18.50 (min.-max, 0.00-36.00]; respectively). The OHIP-14 scores (mean +/- SD) were significantly associated with the symptoms of bleeding gums (13.64 +/- 9.39), sore gums (18.00 +/- 10.47), swollen gums (17.42 +/- 10.91), bad breath (15.82 +/- 9.44), loose teeth (20.00 +/- 8.66) and drifting teeth (24.56 +/- 8.46). Conclusions This study demonstrates a significant association between OHRQoL and periodontitis. Stage-grade of periodontitis and its symptoms were associated with poor quality of life.Item Effects of Treatment Adherence on Quality of Life in Hypoparathyroid Patients(2021) Bagir, Gulay Simsek; Haydardedeoglu, Filiz Eksi; 33694151Objectives This study aimed to evaluate the current situation of hypoparathyroid patients and to investigate the relationship between treatment adherence and quality of life. Study design Prospective, multicentre study. Methods Adult patients presenting with the diagnosis of hypoparathyroidism to 20 different endocrinology clinics were included. They were receiving conventional therapies for hypoparathyroidism, using calcium, active vitamin D, and magnesium. We collected data on demographic features, disease- and treatment-related information, and results of routine laboratory tests, treatment adherence, and presence of complications. Beck Depression Inventory, Beck Anxiety Inventory, and Short Form-36 quality of life assessments were administered. Results Among the 300 patients studied, 60.7 % were adherent to their treatment, and 34.1 % had complications. Anxiety and depression scores were significantly higher in non- adherent versus treatment-adherent patients (p < 0.001 and p = 0.001, respectively). Most of the domains of quality-of-life scores were also significantly lower in non-adherent patients. Both anxiety and depression scores showed significant, negative correlations with serum calcium and magnesium concentrations ( r = -0.336, p < 0.001 and r = -0.258, p < 0.001, respectively). Conclusions Nearly 40 % of the patients were non-adherent to conventional treatment for hypoparathyroidism, and such patients had higher anxiety and depression scores and poorer quality of life scores. Conventional treatment might not be sufficient to meet the needs of patients with hypoparathyroidism. In addition to seeking new therapeutic options, factors influencing quality of life should also be investigated and strategies to improve treatment adherence should be developed.Item Health-related Quality of Life Assessment in Patients with Malignant Gliomas(2021) Taskiran, Emine; Kemerdere, Rahsan; Akgun, Mehmet Y.; Cetintas, Semih C.; Alzada, Orkhan; Kacira, Tibet; Tanrıverdi, Taner; 34979651Background: High-grade gliomas have limited time of survival despite aggressive treatment. Patients experience a decline in their physical and mental capacities, affecting their quality of life (QoL), and require proper therapeutic strategies. Objective: To assess the QoL of malignant glioma patients before and after the treatment in a longitudinal study of six months. Methods and Material: Forty-nine patients who were pathologically diagnosed with glioblastoma and anaplastic glioma according to WHO 2016 were included in this prospective study. The assessment of quality of life was done using the European Organization for Research and Treatment of Cancer (EORTC) quality of life (QoL) questionnaire core-30 prior to surgery, 1 and 5 months after the operation. Results: The decline in Karnofsky scores of the patients was statistically significant. Among the symptom scales, fatigue was more prominent after surgery while pain was noticeable during chemotherapy which was correlated with increased age. The mean overall QoL scores showed a clinically significant decline during the postoperative period. The functional scores demonstrated a significant decline in between all periods. Sex was significantly correlated with preoperative emotional and physical functioning. The patients with right-sided lesions had higher mean scores for social and cognitive functioning. Conclusions: Low KPS, older age, and female gender may affect cancer symptoms and physical and social activities in malignant glioma patients. Cognitive functions as well as social and occupational roles gradually decline during the first six months of treatments. Overall QoL of high-grade glioma patients deteriorates especially after radiotherapy and during the first months of chemotherapy.