Wos Kapalı Erişimli Yayınlar
Permanent URI for this collectionhttps://hdl.handle.net/11727/10753
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Item The Role of Nutritional and Dietary Habits in Etiology in Pediatric Vocal Fold Nodule(2022) Korkmaz, Muge Ozcelik; Tuzuner, ArzuObjectives. In pediatric pediatric vocal fold nodule (VFN) patients, different causes have been suggested in the development of the vocal cord nodule, including laryngopharyngeal reflux (LPR). It is known that the content of consumed foods, obesity, and other dietary behaviors are among the risk factors for the devel-opment of reflux. The aim of this study was to evaluate dietary and food consumption habits in pediatric VFN patients.Methods. This prospective-controlled study included 50 children with VFNs (age range 5-14 years) and 50 age-matched children without any voice disorders as a control group. BMI values of each participant were evaluated according to age-percentile range. The voice usage habits and personality structure of all the children were ques-tioned. All patients underwent laryngeal examination and voice analysis. The Turkish Pediatric Voice Handicap Index (t-PVHI) and Child Voice Handicap Index-10 (t-CVHI) were completed by patients or their parents. The examination findings of all patients were evaluated with the reflux finding score (RFS), and their complaints were questioned with the reflux symptom index (RSI). In addition, eating and drinking at night, fast eating and exces -sive food consumption habits and the frequency of consumption of packaged foods defined as junk food, carbon-ated beverage were questioned. The data obtained were compared statistically between the two groups.Results. There was no significant difference between the study and control groups in terms of age, gender distri-bution, median BMI value, voice usage habits, and personality structure. In the study group, t-PVHI, t-CVHI, jit-ter, schimmer values, the mean RFS, and RSI scores were significantly higher than those of the control group. The number of children with high consumption of junk food and carbonated drinks was higher in the study group. There was no significant difference between the two groups in terms of dietary habits.Conclusion. Food consumption habits may play a role in childhood voice problems in this population.Item Differentiation of Memory Processing Stages and Effect of Demographic Variables with Alternative Scoring Approaches To The Rey Auditory Verbal Learning Test(2022) Karakas, Sirel; Bakar, Emel Erdogan; Dogutepe, Elvin; Can, Handan; Kaskati, Tolga; 35670663Background The Rey Auditory Verbal Learning Test (RAVLT) is the third most popular verbal memory test and the tenth most frequently used neuropsychological test. The original scoring system of RAVLT does not differentiate stages of memory processing, but a recently developed composite scoring system has this potential. The objectives were to compare the two systems in terms of their capacity to differentiate the stages of memory processing and to study the effect of demographic variables on the learning trials (T) of the Turkish form of RAVLT (T-RAVLT). Method The sample consisted of 600 Caucasian Turkic adults, who were categorized into three levels of age, three levels of education, and two levels of gender. Individual administration of T-RAVLT was performed using the standard procedures of RAVLT. Results The components in the exploratory factor analysis (EFA) and latent variables in the confirmatory factor analysis (CFA) of the original scores were consistent with sequentially ordered T-RAVLT stages. Demographic variables (age, education, and gender) affected performances in all of the learning trials. The composite scores revealed retrieval and retention as separate components, but these scores could not be predicted from the relevant T-RAVLT scores. Conclusions Findings recommend a combined utilization of the two scoring systems: The original system to provide scores on the performance at each stage of T-RAVLT and the combined system to provide separate scores on learning, retention, and retrieval, the three stages of memory processing. A selective effect of demographic variables on T1 was not observed, indicating a need for cross-cultural studies that are meticulously controlled for age and education.Item Comparison Of Clinical Characteristics Of Second And Third Peaks Of COVID-19 Pandemic: Effects Of Vaccination And Preventive Measures(2022) Ozdemir, Ozer; Arslan, Atakan; Bulbul, Hande M.; Ozdemir, PelinBACKGROUND: Understanding the differences in consequent peaks of COVID-19 may guide us for better predicting future disease characteristics. In this study, we aimed to compare clinical and radiological characteristics as well as out-comes of hospitalized patients with the diagnosis of COVID-19 in second and third peaks of disease.METHODS: We retrospectively included 303 hospitalized patients with COVID-19. The study population was examined in two groups: patients hospitalized between October 2020 and January 2021 during second peak and patients hospital-ized between March and June 2021 during third peak.RESULTS: There were 171 patients in group 1 and 132 patients in group 2. The patients in group 2 were younger (64 +/- 13.27 vs. 56.02 +/- 15.39, respectively; P<0.001) and female proportion was higher (64.9% and 48.5% males; P=0.005). Smoking history and presence of comorbidities were less in group 2 (41.5% vs. 25.7%, P=0.008; and 78.5% vs. 59.1%, P<0.001) and symptom duration was shorter (median 7 days vs. 6 days, P=0.039). CT severity scores, LDH, CRP, D-di-mer, Ferritin, and creatinine levels were lower in group 2 (P=0.003, P=0.008, P<0.001, P<0.001, P<0.001, respectively), and mortality ratio was lower (N.=39 [28%] vs. N.=15 [11.4%], P=0.01). Duration of hospital stay and need for intensive unit care were similar across groups (median 8 days vs. 7 days, P=0.673 and N.=39 [22.8%] vs. N.=33 [25.2%], P=0.683).CONCLUSIONS: Although duration of hospital stay was lower in third peak, clinical severity scores and prognostic markers were lower compared with second peak. These may reflect the increased proportion of immunized people, and the effect of preventive measures.Item Pediatric T-cell Lymphoblastic Leukemia/Lymphoma Diagnosed at Routine Adenoidectomy Specimen(2023) Kara, Iike; Ramadan, Saime; Senkal, Evrim; Kocdor, Pelin; 36476077Postoperative routine pathologic evaluation of tonsillectomy and adenoidectomy specimens rarely reveals a diagnosis of malignancy. The object of this case report is to highlight this rare clinical occurrence. A 4-year-old boy presented with symptoms of sleep-disordered breathing and had a history of recurrent tonsillitis. Physical examination revealed adenoid hypertrophy and Brodsky Grade 1 bilateral tonsillar hypertrophy. The patient underwent adenoidectomy and tonsillectomy. The adenoids were found to be MAGS Grade 4 (Modified Adenoid Grading System) hypertrophic causing 100% obstruction. After the histologic examination, T-cell lymphoblastic leukemia/lymphoma was diagnosed. Proper treatment allowed full recovery. Currently, no consensus has been made about routine pathological evaluation. To achieve a cost-effective and precautionary approach, we recommend pathological follow-up of cases with unusual intraoperative findings with/without clinical malignancy suspicion.Item Clinical Effectiveness Of Buccally And Palatally Anchored Maxillary Molar Distalization: The Miniscrew-Supported 3-Dimensional Maxillary Bimetric Distalizing Arch Vs The Beneslider(2022) Tuncer, Nilufer Irem; Arman-Ozcirpici, Ayca; 36457217Introduction: This study aimed to investigate the dentoalveolar and skeletal changes achieved with a novel miniscrew-supported 3-dimensional maxillary bimetric distalizing arch (3D-MBDA) and the Beneslider. In addition, the study aimed to compare these changes between each other and with an untreated control group. Methods: Sixty-five patients with bilateral Class II molar relationship and fully-erupted maxillary second molars were included in the study. Of these patients, 23 received the miniscrew-supported 3D-MBDA (group 1), 21 received the Beneslider (group 2), and 21 served as untreated control subjects (group 3). Lateral cephalometric films and dental casts, taken at the beginning and the end of maxillary molar distalization, were analyzed to study the differences between the groups. Results: The crown distalization of the first molars was similar between the treatment groups (group 1, 3.1 mm; group 2, 3.3 mm); however, root distalization was significantly more in group 1 (5 mm) when compared with group 2 (1.7 mm). The first molars tipped 6.2 degrees in the mesial direction in group 1 and 8.2 degrees in the distal direction in group 2. The mesiobuccal cusp tip of the first molars extruded for 1.2 mm and increased vertical dimensions in group 2, whereas it intruded for 1.7 mm in group 1. Meanwhile, aforementioned parameters presented insignificant changes throughout the observation period in the control group. Inter-first molar width increased significantly in group 2 (2.7 mm). Distalization time was similar between the groups (group 1, 14 months; group 2, 15 months). The distalization rate was higher in group 2 (0.27 mm/mo) than in group 1 (0.23 mm/mo) measured from the crowns; however, it was similar between the groups (group 1, 0.25 mm/mo; group 2, 0.19 mm/mo) when measured from the trifurcation point. Conclusions: The miniscrew-supported 3D-MBDA was more effective in distalizing molar roots and maintaining vertical parameters and dental arch width while tipping the molars mesially. In contrast, the Beneslider distalized molar crowns faster, resulting in significant distal tipping. (Am J Orthod Dentofacial Orthop 2022;162:e337-e348)Item Letter To Editor in Regard to Recent Published Study of Abed Et Al. Titled 'The Association Between Dental Arch Length And Oral Health-Related Quality of Life in Head And Neck Cancer Patients Post-Radiotherapy'(2023) Yilmaz, Busra; Somay, Efsun; https://orcid.org/0000-0003-0633-5648; 36222114Item The Effect Of Kefir Enrichment With Arthrospira Platensis And Chlorella Vulgaris On Kefir Microbiota, Antioxidant, And Physicochemical Properties(2022) Kahraman Ilikkan, Ozge; Bagdat, Elif SeymaThis study evaluated the effect of Arthrospira platensis and Chlorella vulgaris on kefir microbiota, total phenolic content, antioxidant activity, and physicochemical properties such as pH, Brix, total dry matter, and titratable acidity. The results showed that the addition of algae at concentrations of 0.5% (w/v) and 1% (w/v) to the kefir did not change the acceptable physicochemical properties of kefir. The acidity of the microalgae-enriched kefirs increased with increasing algae concentration. Total phenolic content and antioxidant activity of all kefir samples fortified with algae were higher than those of the control. However, the addition of A. platensis exhibited better prebiotic activity than C. vulgaris on kefir microbiota during storage. Principal component analysis and overall results showed that A. platensis was a better candidate for improving the nutritional value of kefir.Item Importance of Laparoscopy in Predicting Complete Cytoreduction at Advanced Stage Ovarian Cancer(2022) Durdag, Gulsen Dogan; Alemdaroglu, Songul; Baran, Safak Yilmaz; Serbetcioglu, Gonca Coban; Ozmete, Ozlem; Ezer, Ali; Celik, Husnu; https://orcid.org/0000-0003-4335-6659Purpose Laparoscopy has been used in evaluation of ovarian cancer to assess the extent and surgical resectability of the disease, and to avoid futile laparotomy, where primary cytoreduction is not suitable. Aim of this study is to investigate the contribution of laparoscopy in predicting 'no gross residue' in advanced stage ovarian cancer. Methods Data of advanced stage ovarian cancer patients, who underwent diagnostic laparoscopy for prediction of complete cytoreduction due to an alternative model, are analyzed retrospectively. Accordingly, in the absence of obvious mesenteric retraction or extensive tumoral implants on small intestine in laparoscopic assessment, cases were deemed surgically resectable, and the operation was continued with laparotomy to achieve complete cytoreduction. Clinical features of the patients, surgical details, complete and optimal cytoreduction rates, and perioperative complications were evaluated. Results Out of 243 patients with advanced stage ovarian/tubal/peritoneal cancer, laparoscopy was performed at 93 patients, 77 of whom underwent primary cytoreduction subsequently. Complete cytoreduction (no gross residue) and optimal cytoreduction (< 1 cm residual tumor) rates were 75.3 and 100%, respectively. None of the patients had suboptimal surgery. Morbidity and mortality rates were acceptable. Conclusion Laparoscopic evaluation prior to cytoreductive surgery can highly contribute to prediction of complete or optimal cytoreduction in suitable patients. However, experience and skills of the surgeon, as well as technical equipment of the center, may affect surgery; therefore, the model to predict residual tumor should be individualized according to the set up and the surgical team of each center.Item Left atrial deformations: So clinically relevant(2022) Donal, Erwan; Sade, L. Elif; Kosmala, Wojciech; 35662559Item How hematopoietic stem cell transplantation activity was affected during the pandemic? JACIE accredited center reflex(2022) Kozanoglu, I.; Tepebasi, S.; Kursun, E.; Sen, N.; Unsal, Z. E.; Kis, C.; Boga, C.; Yesilagac, H.; Demiroglu, Y. Z.; Pocan, G.