Scopus Açık Erişimli Yayınlar
Permanent URI for this collectionhttps://hdl.handle.net/11727/10760
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Item Factors associated with progression of depression, anxiety, and stress-related symptoms in outpatients and inpatients with COVID-19: A longitudinal study(2022) Alici, Yasemin Hosgoren; Cinar, Gule; Hasanli, Jamal; Ceran, Selvi; Onar, Deha; Gulten, Ezgi; Kalkan, Irem Akdemir; Memikoglu, Kemal Osman; Celik, Casit Olgun; Devrimci-Ozguven, Halise; 0000-0003-3384-8131; 0000-0003-1364-625X; 0000-0002-7984-2440; 0000-0002-7190-5443; 35593144; AAJ-8113-2021; AAK-3227-2021; AAD-5477-2021It is known that there is an increase in the frequency of psychiatric disturbances in the acute and post-illness phase of coronavirus disease (COVID-19). Comorbid psychiatric symptoms complicate the management of patients and negatively affect the prognosis, but there is no clear evidence of their progress. We aimed to determine psychiatric comorbidity in inpatients and outpatients with COVID-19 and recognize the factors that predict psychiatric comorbidity. For this purpose, we evaluated patients on the first admission and after 4 weeks. We investigated psychiatric symptoms in outpatients (n = 106) and inpatients (n = 128) diagnosed with COVID-19. In the first 7 days after diagnosis (first phase), sociodemographic and clinic data were collected, a symptom checklist was constructed, and the Hospital Anxiety and Depression Scale (HADS) and the Severity of Acute Stress Symptoms Scale (SASSS) were applied. After 30-35 days following the diagnosis, the SASSS and the HADS were repeated. In the first phase, the frequency of depression and anxiety were 55% and 20% in inpatients, and 39% and 18% in outpatients, respectively. In the second phase, depression scores are significantly decreased in both groups whereas anxiety scores were decreased only in inpatients. The frequencies of patients reporting sleep and attention problems, irritability, and suicide ideas decreased after 1 month. Patients with loss of smell and taste exhibit higher anxiety and depression scores in both stages. Our results revealed that the rate of psychiatric symptoms in COVID-19 patients improves within 1 month. Inpatients have a more significant decrease in both depression and anxiety frequency than do outpatients. The main factor affecting anxiety and depression was the treatment modality. Considering that all patients who were hospitalized were discharged at the end of the first month, this difference may be due to the elimination of the stress caused by hospitalization.Item The Relationship Between Vitamin B12 and Vitamin D Levels and Subjective Cognitive Complaints in Patients with First Episode Major Depressive Disorder(2021) Ulusoy, Selen Isik; Horasanli, Bahriye; Kulaksizoglu, Sevsen; 0000-0003-3142-1011Objective: Cognitive dysfunction is an important component of major depressive disorder (MDD). The aim of this study is to investigate the relationship between vitamin B12 and D and subjective cognitive complaints in patients with first-episode MDD. Method: In this cross-sectional study, patients (n=120) diagnosed with first-episode MDD filled out self-report questionnaires that evaluate subjective neurocognitive symptoms (Perceived Deficits Questionnaire-Depression [PDQ-D] and British Columbia Cognitive Complaints Inventory [BC-CCI]). Disease severity was evaluated using the Hamilton Depression Rating Scale (HDRS). Serum 25-OH vitamin D and vitamin B12 levels were measured using a chemiluminescence microparticle immunoassay technology. Results: The PDQ-D and BC-CCI scores were significantly higher in patients with combined vitamin B12 and D deficiency than patients with normal vitamin levels. We found a negative correlation between vitamin B12 level and HDRS, BC-CCI and PDQ-D scores. In addition, there was a positive correlation between HDRS scores and PDQ-D and BC-CCI scores. Linear regression analysis revealed that HDRS score and vitamin B12 level have influence on PDQ-D and BC-CCI scores. Conclusion: In this study, it was found that subjective cognitive impairment was significantly higher in MDD patients with both of vitamin B12 and vitamin D deficiency. Vitamin B12 levels were also associated with depressive symptom severity and subjective cognitive impairment. Depression severity and vitamin B12 level were found to be significant predictors of subjective cognitive impairment. Our findings highlight the importance of depression severity and vitamin B12 and D levels during routine clinical evaluation of MDD.Item Frequency of headache among university students and its effect on daily living activities(2021) Ocal, Ruhsen; Iyigundogdu, Ilkin; Kirnap, Nazli Gursoy; Talu, Irem; Alkislar, Defne; Aras, Dilay; Uner, Aylin; Uzunalioglu, Ece; 0000-0001-7860-040X; AAJ-2053-2021Background & Objective: Headache is a common symptom in the general population. The aim of this study was to investigate the frequency of headache among a university students population in Ankara, Turkey; and to evaluate the factors affecting the headache and the effect of headache on students' quality of life. Methods: A face-to-face questionnaire was applied to all participants in the study. In the questionnaire, demographic data, personal background and family history of the participants as well as the presence of headache were collected. The characteristic features of the headache, accompanying symptoms and medication use for the headache were evaluated. The 36-Item Short Form Survey (SF-36), Beck depression and Beck anxiety scales were administered to all participants. Results: Three hundred and sixty six university students participated in the study. Three hundred and thirty one participants (90.4%) had experienced headache at least once in their lifetime. Headache was more common in women (p 0.01). Depression was found in 135 (36.9%) students with the Beck depression scale, and anxiety was found in 236 (64.5%) students with the Beck anxiety scale. There was no relationship between depression or anxiety and the presence of headache (p 0.05). Emotional role difficulties, social function, pain and general health scores were significantly lower on SF-36 in the group with headache (p<0.05) than without headache. Conclusion: Headache adversely affects the quality of life and is a common symptom among university students, independent of depression and anxiety.Item Analysis of Quality of Life, Depression, and Sexual Function in Patients on the Liver Transplant List(2021) Fidan, Cihan; Akdur, Aydincan; Kirnap, Mahir; Selcuk, Haldun; Yildirim, Sedat; Moray, Gokhan; Haberal, Mehmet; 0000-0002-3462-7632; 0000-0002-8726-3369; 34609310; AAJ-8097-2021; AAA-3068-2021Background: I he only treatment in patients developing liver failure is liver transplantation. According to the Ministry of Health, the number of patients waiting for a liver transplantation is 2141, the average waiting period for liver transplantation is approximately 5 years, and 15-18% of these patients lose their life while waiting for transplantation. In these patients, limitations in daily activities and depression-anxiety are commonly found. The aim of this study was to analyze life quality, depression symptoms, and existence of sexual functional disorders of patients waiting for liver transplantation. Methods: A total of 74 patients, who were registered in Baskent University Hospital between 2015 and 2018, were included into the study. Short Form-36, Beck Depression Inventory, and Arizona Sexual Experiences Scale were applied to 56 patients who approved study. Results: Most of the patients were male (64.3%), and the mean age was 46 (18-64). Short Form-36 scores were low in all patients. The mean Beck Depression Inventory score of patients was found as 18.4 +/- 11.3, and they were suffering from moderate depressive symptoms. According to Arizona Sexual Experiences Scale, total mean scores of males was found as 16.3 +/- 5.5, and for females, it was 19.5 +/- 5.3 with a statistically significant difference (P < .05). It was found that sexual dysfunction mostly had moderate to mild. Conclusion: Depression and sexual dysfunction are common in patients with chronic liver diseases, and their life qualities deteriorate significantly. It is anticipated that evaluation of these patients in terms of psychological issues and sexual dysfunction will increase their quality of life during the organ waiting period and affect their well-being post-transplant.Item Increased Levels of Anxiety, Depression, and Secondary Trauma in Radiation Oncologists during COVID-19 Pandemic: A Preliminary Report from Turkey(2021) Topkan, ErkanOBJECTIVE We surveyed the anxiety, depression, and secondary trauma levels of Turkish Radiation Oncologists related with COVID pandemics. METHODS An anonymous online questionnaire survey was created to evaluate levels of depression, anxiety, and secondary trauma among Turkish Radiation Oncologists. The survey included demographics and occupational status, Secondary Traumatic Stress Scale (STSSS), The Beck Depression Inventory (BDI), The Beck Anxiety Inventory (BAI), and State-Trait Anxiety Inventory (STAI). RESULTS Seventy-two respondents provided the power of about 91.4% for the significance level of 0.05. The variance homogeneity was checked by the Levene test, the effect of COVID-19 on psychology is higher in the group of >19 (9.02 +/- 0.820), as well as the effect of social isolation (8.02 +/- 1.622), the STSS scores (34.28 +/- 9.062), the STAIS scores (60.46 +/- 5.296), the STAIT scores (82.21 +/- 9.298), the BDI scores (22.68 +/- 2.788), and the BAI scores (21.04 +/- 9.321). The multiple regressions to estimate BDI revealed statistically significant effects in STAIS, BAI, and STAIT. There is a significant correlation between STSS, STAIS, STAIT, BDI, BAI, the effect of COVID-19 on psychology, and the effect of social isolation. CONCLUSION We have established one of the first studies demonstrating the effects of COVID-19 pandemic on depression, anxiety levels, and secondary trauma on a special physician population, the Radiation Oncologists, who specifically do not directly take part in COVID19 management.Item Seasonal Variations in Obsessive-Compulsive Disorder: Analysis of Prospective-Clinical Data(2021) Altintas, Ebru; Kutuk, Meryem Ozlem; Tufan, A. Evren; 34526841Introduction: Few studies have investigated potential seasonal changes in anxiety disorders. This study aimed to evaluate whether seasonal changes influence the severity of obsessive and compulsive symptoms in obsessive-compulsive disorder (OCD). The relationship between comorbid anxiety and depression symptoms and the seasons was also investigated. Furthermore, we compared the differences between retrospective data reliant on patients' recall and data obtained by prospective observation. Methods: The Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Y-BOCS Symptom Checklist, Beck Anxiety Scale, and Beck Depression Scale were administered to 148 patients with OCD in each of the four seasons over a year. The relationships between the seasons and the scales based on retrospective observations of the patients, and between the seasons and scales based on prospective data collected over the year were analyzed. Scores from clinical assessments were compared between the different seasons. Results: The severity of obsessive and compulsive symptoms, did not show seasonal changes. Multi-level growth models suggested that the change in Y-BOCS Total scores across seasons could be explained by subjective symptoms of depression and anxiety and their interactions. Importantly, results obtained using prospective observations from structured clinical assessment differed from those obtained using retrospective observations of patients. Conclusions: Our study does not support the existence of seasonal variations in symptoms of OCD. Future studies are needed to delineate seasonal variations in OCD symptoms.