PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4810
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Item Daptomycin Versus Teicoplanin in the Treatment of Osteomyelitis: Results of the Goztepe Retrospective Cohort Study(2021) Sipahi, O. R.; Erdem, H. A.; Kahraman, H.; Kursun, E.; Suntur, B. M.; Demirdal, T.; Nemli, S. A.; Dizbay, M.; Ulug, M.; Oztoprak-Cuvalci, N.; Arda, B.; Quliyeva, G.; Tasbakan, M.; Uysal, S.; Sipahi, H.; Aydemir, S.; Ulusoy, S.; 33870888Objectives: Daptomycin is highly effective against Gram-positive multidrug-resistant bacteria. Publications on daptomycin in osteomyelitis treatment are limited. Patients and methods: In this multicenter retrospective cohort study, the aim was to evaluate the outcomes of osteomyelitis cases having received daptomycin or teicoplanin. This multicenter retrospective cohort study gathered data from seven centers located in five cities of Turkey. Study inclusion criteria were as follows: (a) magnetic resonance imaging and/or direct X-ray revealed osteomyelitis or biopsy pathologic examination results concomitant with osteomyelitis. Chi-squareand Student t-tests were used for statistical comparison. Results: A total of 72 patients, 38 cases in the daptomycin group and 34 cases in the teicoplanin group diagnosed with osteomyelitis fulfilling the study inclusion criteria, were included in the study. Clinical success at the end of induction therapy was achieved in 32/38 cases in the daptomycin cohort vs. 30/34 cases in the teicoplanin cohort (p: 0.73). Conclusion: Although this is a limited experience in a small but well-defined cohort, our data suggest that daptomycin may be a safe alternative to glycopeptides in osteomyelitis treatment. A randomized controlled clinical study involving larger cohorts may increase the available evidence.Item Effect of cone beam computed tomography voxel size and dental specialty status on the agreement of observers in the detection and measurement of periapical lesions(2021) Kamburoglu, Kivanc; Koc, Emre; Sonmez, Gul; Elbahary, Shlomo; Rosen, Eyal; Tsesis, Igor; 34120879Objective. To compare observer agreement between endodontists and oral and maxillofacial radiologists (OMRs) in the detection and measurement of periapical lesions as depicted in cone beam computed tomography (CBCT) with 2 voxel sizes. Study Design. In total, 256 CBCT images of maxillary molars were evaluated by 2 endodontists and 2 OMRs. Images were obtained at voxel sizes of 0.2 and 0.4 mm. Observers evaluated 64 endodontically and 64 nonendodontically treated teeth for the presence of periapical lesions using a 5-point confidence scale. Weighted k values were calculated to determine intra- and interobserver agreement. Intraclass correlation coefficients (ICCs) were calculated to assess intra- and interobserver agreement in width and height measurements of the lesions. Results. Intraobserver agreement ranged from fair to almost perfect, with k values higher for the OMRs than for the endodontists. Interobserver agreement between endodontists ranged from fair to moderate at the 0.2mm voxel size and was slight at 0.4 mm. Agreement between OMRs was almost perfect at 0.2 mm and ranged from substantial to almost perfect at 0.4 mm. ICC was excellent for all observers in all conditions. Conclusions. Intra- and interobserver reliability was affected by voxel size and specialty. Correlation for measurements exhibited no variation.Item Evaluation of Stress Distribution of Four Different Fixation Systems at High- and Low-Level Subcondylar Fractures on a Nonhomogenous Finite Element Model(2020) Ergezen, Ezgi; Akdeniz, Sidika Sinem; 32445628Purpose: The aim of the present study was to provide insight into a suitable fixation system for subcondylar fractures located at different levels. Materials and Methods: High and low subcondylar fractures were simulated on a nonhomogenous mandibular model, and rhombic, trapezoid, and lambda plates and 2 miniplates were used for fixation. The stress in the bone and displacement of the fracture site were measured using finite element analysis. Results: For both high and low subcondylar fractures, the lowest von Mises stress was measured in the rhombic plate system. For high subcondylar fractures, the highest tension in the cortical bone was measured in the trapezoid plate system, and the highest compression was measured in the rhombic plate system. For low subcondylar fractures, the highest tension in the bone was measured in the rhombic system and the highest compression was measured in the trapezoid system. In both high and low subcondylar fracture models, the least displacement amount was measured in the 2-plate system. Conclusions: The results of the present study have shown that the rhombic plate system might be the proper choice for high subcondylar fractures and the 2-plate system might provide better results for low subcondylar fractures. (C) 2020 American Association of Oral and Maxillofacial Surgeons